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4421
Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”
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4422
DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer...
Published 2024“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”
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4423
Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …”
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4424
Table 1_Therapeutic effects of composite probiotics derived from fermented camel milk on metabolic dysregulation and intestinal barrier integrity in type 2 diabetes rats.docx
Published 2025“…</p>Results<p>High-dose CPCM significantly increased BW by 22.2% (p < 0.05) and reduced FBG by 6.5 mmol/L (p < 0.001). …”
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4425
Source data.zip
Published 2025“…In vivo, melatonin significantly increased MT1R (melatonin receptor 1A) expression in BPA-treated mouse testicular cells and the content of catalase, superoxide dismutase 2, and glutathione, while decreasing the level of malondialdehyde. …”
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4426
Figure 3 from Mucosal Microbiome Markers of Complete Pathologic Response to Neoadjuvant Therapy in Rectal Carcinoma
Published 2025“…<p>Mucosal microbiome α diversity is decreased with high radiation injury histology score. …”
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4427
Data Sheet 1_Lethal and sublethal effects of chemical and bio-insecticides on Spodoptera frugiperda adults: new perspectives for “attract-and-kill” control strategies.pdf
Published 2025“…Sublethal exposure to chlorantraniliprole significantly reduced larval and pupal development durations, decreased pupal weights, and shortened adult longevity in the offspring, without significantly affecting larval mortality, pupation rate, or emergence rate. …”
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4428
community_experiment_and_pure_culture.xlsx
Published 2025“…In both experiments, PE and PVC significantly reduced viral abundances. However, their effects on bacterial abundances were context-dependent. …”
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4429
Data Sheet 1_Enhancing spelling competence for English as a foreign language young learners through digital escape rooms.docx
Published 2024“…Mixed methods analyses found that spelling competence in the intervention group as opposed to the control group improved in the post-test and continued to improve significantly in the delayed post-test. …”
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4430
Manuscript FAM22 for submission.docx
Published 2025“…<p dir="ltr">In this study, two-stage combustion tests were carried out in a hot water boiler located within the greenhouse facility of an enterprise operating in Aydın, Turkey. …”
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4431
Evaluation of heavy hydrocarbon liquid in the Eastern Dahomey Basin, Southwestern Nigeria (case study of Agbabu Bitumen in Ondo State)
Published 2025“…Methanol reduced the saturates content and significantly raised the asphaltene content, keeping the mixture viscosity high. …”
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4432
Data Sheet 2_Enhancing spelling competence for English as a foreign language young learners through digital escape rooms.docx
Published 2024“…Mixed methods analyses found that spelling competence in the intervention group as opposed to the control group improved in the post-test and continued to improve significantly in the delayed post-test. …”
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4433
Table1_Optimizing active recovery strategies for finger flexor fatigue.xlsx
Published 2024“…</p>Results<p>The impulse (Nꞏs) significantly decreased from the first to third trials after walking (−18.4%, P = 0.002, d = 0.78), climbing (−29.5%, P < 0.001, d = 1.48), and hanging (−27.2%, P < 0.001, d = 1.22). …”
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4434
Data Sheet 1_Diethyl butylmalonate attenuates cognitive deficits and depression in 5×FAD mice.docx
Published 2024“…Novel object recognition, Y-maze spatial memory, Morris water maze and nest building tests were used to evaluate cognitive function. Moreover, the tail suspension test, forced swimming test, open field test and the elevated plus maze test were used to assess depression. …”
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4435
Proteomic analysis for busulfan-induced spermatogenesis disorder
Published 2024“…Western blotting revealed that LDHAL6B protein significantly increased at 10 days, decreased from 20 to 60 days, and then gradually elevated from 70 to 80 days after busulfan treatment.…”
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4436
DataSheet1_Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.pdf
Published 2024“…</p>Findings<p>Low concentrations of CL-10 in cord sera (<462 ng/ml corresponding to the 10<sup>th</sup> percentile) were significantly associated with births at GA ≤32 weeks. …”
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4437
Supplementary Material for: Alpinia galanga essential oil mitigates gentamycin-induced renal injury: in silico and in vivo studies
Published 2025“…Results: Network Pharmacology suggested Toll-like receptors 4 (TLR4), and Interleukin-1beta (IL-1β) as potential targets of Gal EO components in Genta induced renal toxicity. Gal EO significantly decreased Cr, uric acid, BUN, CysC, NGAL and Kim-1 and the urine albumin/creatinine ratio. …”
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4438
Effect of session on winning model parameters for set size = 2 and set size = 4 for both male and females.
Published 2024“…Use of one-back strategy parameters changed significantly across sessions for male mice with (C) S1 “Inappropriate Lose Shift” decreasing across sessions, <i>p</i> = 0.01 (D) S2 = S4 “Stimulus Insensitive Win Stay” increasing, <i>p</i> = 0.009 and (E) S3 “Inappropriate Lose Stay” decreasing, <i>p</i> < 0.0001. …”
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4439
Supplementary Material for: Metabolic analysis of three-dimensional cultured gastrointestinal cancer cells suggests that L-arginine inhibits tumor growth by affecting the urea cycl...
Published 2024“…In OE33, S phase cells (determined using BrdU) were significantly reduced. In a comprehensive metabolic analysis of OE33, citrulline/ornithine levels were significantly lower in arginine-treated than in untreated cells. …”
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4440
Objective Quality Assessment of the Capsulorhexis – A Novel Augmented Reality Tool for Trainees and Experts
Published 2025“…The augmented reality group was statistically significantly better in terms of circularity than the Expert support (Mann–Whitney’s <i>U</i>-test: <i>p</i> = .00175) and the No support group (Mann–Whitney’s <i>U</i>-test: <i>p</i> = .00268). …”