Effect of Gasdermin-D inhibition on CER-induced pyroptosis in P_i<i>‐</i>treated VSMCs. by Razia Rashid Rahil (22772495)

“…<p>Summarized bar graphs showed DIS significantly decreased mRNA expression of pyroptotic markers (A) NLRP3 (B) GSDM-D, proinflammatory cytokines (C) IL-1β (D) IL-18, and (E) Lactate dehydrogenase (LDH) release in CER treated P_i‐induced VSMCs. …”

Effect of NLRP3 inhibition on CER-induced pyroptosis in P_i<i>‐</i>treated VSMCs. by Razia Rashid Rahil (22772495)

“…<p>Summarized bar graphs showed MCC950 significantly decreased mRNA expression of pyroptotic markers (A) NLRP3 (B) GSDM-D, proinflammatory cytokines (C) IL-1β (D) IL-18, and (E) Lactate dehydrogenase (LDH) release in CER treated P_i‐induced VSMCs. …”

Further characterization of N19 and calcium dependence. by Elham Karamooz (2584474)

“…Pooled data from 2 independent experiments. Significance measured by a paired two tailed <i>t</i> test. …”

Supplementary Material for: Exclusively macular phenotype of non-syndromic MFSD8-related disease: A Case Report by figshare admin karger (2628495)

“…Introduction: The purpose of this report is to highlight the clinical phenotype and imaging findings in a patient with an exclusively macular phenotype of non-syndromic MFSD8-related disease, and to provide clinical evidence for pathogenicity reclassification of a variant of uncertain significance (VUS) MFSD8 c.291G>C (p.Trp97Cys). Case Presentation: A 47-year-old male with progressive vision loss exhibited symptoms indicative of maculopathy. …”

DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx by Abdul Mateen (12055673)

“…Pharmacokinetic parameters such as AUC_0-t, C_max MRT, Vd, and half-life (t_1/2) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar^®). …”

Supplementary Material for: Early initiation of icodextrin reduces peritoneal dialysis-associated peritonitis risk: a retrospective cohort study by Mitsuno R. (20394647)

“…The early use of ICO remained significantly associated with decreased incidence of both peritonitis and TI (hazards ratio [HR], 0.19; 95% confidence interval [CI], 0.06–0.69 and HR, 0.10; 95% CI, 0.01–0.78, respectively) using Cox regression analysis adjusted for potential confounders. …”

Table1_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.docx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Table2_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Table4_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Table3_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Effects of vidarabine, V2E, V3E and V5E on cardiac fibrosis. by Kenji Suita (750993)

“…Statistical significance was analyzed by one-way ANOVA with the Tukey-Kramer’s <i><i>post hoc</i></i> test. …”

Figure 6 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma by Gwendolyn M. Cramer (16964052)

“…<p>PD-1 blockade significantly decreases tumor growth rates in combination with TI/PDT. αPD-1 initiated 1 hour after PDT and continuing 2× weekly for 3 weeks did not significantly alter tumor growth rates. …”

USUV replicates in STAT1-sufficient peripheral tissues leading to spleen and liver pathology. by Amy N. Nelson (21763146)

“…Statistical analysis was performed using one sample t tests comparing USUV RNA detected in samples to the limit of detection. …”

Data Sheet 1_Effect of Fangxia-Dihuang Decoction on doxorubicin-induced cognitive impairment in breast cancer animal model.docx by Xuan Wang (55634)

“…The results of blood routine and cardiac HE staining showed that compared with the 4T1 group, the serum ALT, AST, CK, LDH, and CKMB in DOX group mice were significantly increased (P<0.05). After FXDH administration, all indicators in mice were decreased, but there was no statistical difference. …”

<i>Hif-1α</i> ablation reduces the efficiency of NeuroD1 gene-based therapy and aggravates the brain damage following ischemic stroke by Nashwa Amin (11242159)

“…Meanwhile, <i>Hif-1α</i> ablation significantly decreased the efficiency of NeuroD1 gene-based therapy.…”

Video 1_Effect of Fangxia-Dihuang Decoction on doxorubicin-induced cognitive impairment in breast cancer animal model.mp4 by Xuan Wang (55634)

“…The results of blood routine and cardiac HE staining showed that compared with the 4T1 group, the serum ALT, AST, CK, LDH, and CKMB in DOX group mice were significantly increased (P<0.05). After FXDH administration, all indicators in mice were decreased, but there was no statistical difference. …”

Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Sperm proteins were analyzed using sodium dodecyl sulphate-polyacrylamide gel electrophoresis page (SDS-PAGE) and liquid chromatography-mass spectrometry (LC-MS), and differentially expressed proteins (DEPs) were identified based on significance test results and fold change thresholds. …”

Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Sperm proteins were analyzed using sodium dodecyl sulphate-polyacrylamide gel electrophoresis page (SDS-PAGE) and liquid chromatography-mass spectrometry (LC-MS), and differentially expressed proteins (DEPs) were identified based on significance test results and fold change thresholds. …”

Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Sperm proteins were analyzed using sodium dodecyl sulphate-polyacrylamide gel electrophoresis page (SDS-PAGE) and liquid chromatography-mass spectrometry (LC-MS), and differentially expressed proteins (DEPs) were identified based on significance test results and fold change thresholds. …”

Figure S1-S21 from miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5 by Verena Stiegelbauer (4582930)

“…The miR-196b-5p inhibited DLD1 cells closed the scratch significantly earlier than the inhibitor control cells, whereas the miR-196b-5p overexpression in SW480 resulted in decreased scratch closure (* = significant, p < 0.05; **, p < 0.01; ***, p < 0.001; studentÂ's t-test). …”