Data Sheet 1_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf by Lu Ding (475637)

“…Specific metabolite combinations, such as serine, isoleucine, betaine, PC (5:0/5:0), and LysoPE (18:2), showed high precision in predicting acute ischemic stroke (AIS) (training set AUC = 0.988, test set AUC = 0.971). Glycine-serine-threonine and valine-leucine-isoleucine pathways were significant in diagnosing IS and AIS, and in differentiating ischemic and hemorrhagic strokes, as well as identifying post-stroke depression and cognitive impairment.…”

Data Sheet 3_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf by Lu Ding (475637)

“…Specific metabolite combinations, such as serine, isoleucine, betaine, PC (5:0/5:0), and LysoPE (18:2), showed high precision in predicting acute ischemic stroke (AIS) (training set AUC = 0.988, test set AUC = 0.971). Glycine-serine-threonine and valine-leucine-isoleucine pathways were significant in diagnosing IS and AIS, and in differentiating ischemic and hemorrhagic strokes, as well as identifying post-stroke depression and cognitive impairment.…”

Data Sheet 4_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf by Lu Ding (475637)

“…Specific metabolite combinations, such as serine, isoleucine, betaine, PC (5:0/5:0), and LysoPE (18:2), showed high precision in predicting acute ischemic stroke (AIS) (training set AUC = 0.988, test set AUC = 0.971). Glycine-serine-threonine and valine-leucine-isoleucine pathways were significant in diagnosing IS and AIS, and in differentiating ischemic and hemorrhagic strokes, as well as identifying post-stroke depression and cognitive impairment.…”

Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf by Faruk Hossen (20275670)

“…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …”

DataSheet1_An observational study of lower limb muscle imbalance assessment and gait analysis of badminton players.docx by Ping Huang (30439)

“…Lower limb muscle imbalance can cause gait abnormalities and increase the risk of muscle injury or decreased performance in significantly asymmetrical situations. …”

Data Sheet 1_The relationship between hearing loss and frailty in older adults at risk of cognitive decline: a cross-sectional study.pdf by Rong Tian (397491)

“…</p>Results<p>There were statistically significant differences between frail and non-frail groups for speech frequency hearing threshold, overall central auditory processing score and hearing handicap score, but not for high frequency hearing threshold.…”

Whole 16S rRNA gene sequencing reveals differences in the oral microbiota of healthy individuals infected with oral HPV by Toby I. Maidment (15296219)

“…</p> <p>We demonstrated (1) significant differences in the abundance of <i>Streptococcus salivarius</i> in oral HPV-negative males; (2) males with low-risk HPV had an increased abundance of several species and (3) decreased abundance of <i>Streptococcus salivarius</i> and <i>Streptococcus parasanguinis</i>. …”

Table 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.docx by Yu Qiao (462684)

“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”

Image 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.tif by Yu Qiao (462684)

“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”

“Engineering Rifampicin-Encapsulated Inhalable Microparticles for Precision Tuberculosis Therapy: In Vivo Distribution and Therapeutic Evaluation” by Ruchi Tiwari (6677939)

“…The TB-infected mice, which showed the lung tissue bacterial load was reduced to 3.2 log colony forming unit (CFU) and the levels of TNF-α were decreased while IL-10 levels were increased. With this kind of accelerated stability testing it was ascertained that the type of formulation had a shelf-life of 24 months.…”

Data Sheet 1_Drones outperform dogs for hazing bears: a comparison of carnivore aversive conditioning tools.docx by Wesley M. Sarmento (20620745)

“…These various hazing techniques were successful at stopping undesirable bear behaviors and caused a significant increase in avoidance behavior and distance to human infrastructure. …”

Table 2_Can fostering posttraumatic growth prevent burnout and promote resilience in future nurses?.docx by Jae-Chang Sim (22335904)

“…Although the effect on burnout was not statistically significant, there was a trend for relatively decreased burnout in the treatment group.…”

Table 1_Can fostering posttraumatic growth prevent burnout and promote resilience in future nurses?.docx by Jae-Chang Sim (22335904)

“…Although the effect on burnout was not statistically significant, there was a trend for relatively decreased burnout in the treatment group.…”

H2AK119ub is depleted from facultative heterochromatin as the cerebellum matures. by Aditya Parmar (22331873)

“…<b>(D)</b> Volcano plot depicting H2AK119ub abundance, as detected in normalized CUT&RUN data from early and late cerebellum, within H3K27me peak regions identified by SEACR in the early cerebellum. The significance threshold was a p-value <0.05, as computed using edgeR [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref071" target="_blank">71</a>] and limma [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref072" target="_blank">72</a>] (n = 4). …”

Table_1_Engaging Underserved Communities in COVID-19 Health Equity Implementation Research: An Analysis of Community Engagement Resource Needs and Costs.docx by Nicole A. Stadnick (8788511)

“…Background<p>Meaningful community engagement is instrumental to effective implementation and sustainment of equitable public health interventions. Significant resources are necessary to ensure that community engagement takes place in culturally sensitive, trusted ways that optimize positive public health outcomes. …”

Supplementary file 1_Tacrolimus exposure during the three-month period following allogeneic stem cell transplantation predicts overall survival.docx by Alzbeta Zavrelova (4885270)

“…Tacrolimus volume of distribution was 127.1 L and was not affected by any of the tested covariates, whereas clearance decreased with age according to the equation CL=7.94×e−0.0085×age and was reduced by 23% in patients who underwent repeat transplantation.…”

Image 1_Assessment of microstructural abnormalities in gray and white matter of minimal hepatic encephalopathy patients using diffusion kurtosis imaging and their associations with... by Qing Sun (492552)

“…</p>Results<p>The TBSS analysis results showed that MHE patients had significantly decreased fractional anisotropy (FA) in the temporal part of the left superior longitudinal fasciculus and decreased kurtosis fractional anisotropy (KFA) in the left corticospinal tract and anterior thalamic radiation (p < 0.05, threshold-free cluster enhancement corrected). …”

Supplemental Material For Coronary Microvascular Remodeling in Pressure-Overload RV by Ilham Essafri (21688937)

“…Notably, resistance was significantly higher in male SHAM mice compared to females at baseline, and decreased in males but not in females post-PAB. …”

mRNA levels of CASP family markers (A-E), BCL2 family markers (F-H) and other apoptosis-related markers (I-M) in limbal stromal cells (LSCs) and in Aniridia-LSCs (AN-LSCs), after t... by Shanhe Liu (5251313)

“…Two-way ANOVA followed by Dunnett’s test was used, significant p values are indicated. …”

DataSheet1_Using anti-Müllerian hormone to predict premature ovarian insufficiency: a retrospective cross-sectional study.docx by Yuanxin Huang (20286858)

“…At AMH level below 0.5ng/ml,basal FSH increased significantly with age. At FSH <10 IU/L, AMH levels show a trend of rising and then decreasing with age, reaching a peak at approximately 25 years old and gradually decreasing with age. …”