Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …”

PV interneurons from Shiverer mice show many similarities with the ones from mice that underwent juvenile demyelination. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in Shiverer mice (<i>group x current two-way repeated measures: n = 25/25 cells from 9 mice per group: F(13,624) = 2.303, **p < 0.0056</i>). …”

Juvenile demyelination impairs the maturation of PV interneurons in the PFC. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in cuprizone-treated mice. …”

Adult demyelination has no effect on PV interneuron’s firing rate or failures in autaptic responses. by Sara Hijazi (21656615)

Autapses play a crucial role in PV interneuron’s sustained firing at high frequencies. by Sara Hijazi (21656615)

“…Note that in cuprizone mice there was no difference (<i>group x current two-way repeated measures: n = 19,19,18,18 cells from 9−8 mice per group: F(39,856) = 1.671, p = 0.0068, post-hoc LSD test: *p < 0.05</i>). <b>F</b>. Summary data of the maximum firing frequency per group revealing a decrease in the maximum firing frequency in PV interneurons that do not have autapses (<i>t test of control with vs. without autapse; n = 19 cells from 9 mice per group, *p < 0.01; t test of cuprizone with vs. without autapse; n = 17 cells from 8 mice per group, p = 0.0722</i>). …”

Comparison between juvenile and adult demyelination. by Sara Hijazi (21656615)

“…Juvenile demyelination leads to impairment in PV interneuron maturation whereas adult demyelination induces a decrease in the excitability of PV interneurons. Summary data showing the averaged (± s.e.m) of the following intrinsic properties: (A) Resting membrane potential (RMP) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: *p < 0.05, **p < 0.01, ****p < 0.0001</i>), (B) Input resistance (IR) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0024, post-hoc LSD test: *p < 0.05, **p < 0.01, ***p < 0.001</i>), (C) Sag (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0083, post-hoc LSD test: *p < 0.05, **p < 0.01</i>), (D) Rheobase (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, p = 0.1230, post-hoc LSD test: *p < 0.05</i>) and (E) Action potential (AP) threshold (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, *p = 0.0452, post-hoc LSD test: *p < 0.05</i>), (F) AP half-width (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0058, post-hoc LSD test: **p < 0.01</i>), (G) Average action potential (AP) frequency in response to 0–650 pA current steps illustrating no significant change in S1 PV interneuron firing frequency following juvenile demyelination (<i>group x current two-way repeated measures: n = 36,30,19,24 cells from 9/8/8/6 mice per group: F(39,1,291) = 2.487, ****p < 0.0001</i>) and (H) Maximum firing frequency per group (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: ***p < 0.001, ****p < 0.0001</i>). …”

Juvenile demyelination induces a loss of functional autapses. by Sara Hijazi (21656615)

“…Cuprizone-treated mice show a significant decrease in the percentage of cells showing an autaptic response (<i>Fisher’s exact test; *p = 0.0173</i>). …”

Juvenile demyelination impairs autaptic plasticity. by Sara Hijazi (21656615)

AUT00201 (1 µM) can rescue AP width in cuprizone mice. by Sara Hijazi (21656615)

“…Post-hoc LSD test: *p < 0.05, n.s. p = 0.0957</i>). <b>B</b>. …”

Effect of AUT00201 (1 µM) on PV properties after adult demyelination. by Sara Hijazi (21656615)

Hardy‒Weinberg equilibrium test of rs12529 in the study subjects. by Md. Akeruzzaman Shaon (21511929)

Summary of previous studies in vitamin D and intertrochanteric fractures association and results of our study. by Kamran Alijanpour (20314706)

Subjects:

Baseline characteristics of the study participants and the results of laboratory measurements. by Kamran Alijanpour (20314706)

Subjects:

Comparison of serum vitamin D and calcium levels in patients with stable and unstable intertrochanteric fractures included in this study. by Kamran Alijanpour (20314706)

Subjects:

Compaction test results. by Shoujie Wang (18326754)

“…The results show that the UCS and CBR values enhanced significantly with the increase in curing time. However, the moisture content and pH of the stabilized soil exhibited a decreasing trend. …”

CBR test results. by Shoujie Wang (18326754)

“…The results show that the UCS and CBR values enhanced significantly with the increase in curing time. However, the moisture content and pH of the stabilized soil exhibited a decreasing trend. …”

Descriptive statistics of variables. by Yanling Li (269030)

Subjects:

Matched kernel density function diagram. by Yanling Li (269030)

Subjects:

Matching estimation results of propensity score. by Yanling Li (269030)

Subjects:

Results of baseline regression. by Yanling Li (269030)

Subjects: