Image 9_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”

Image 2_α-Glycerol monolaurate promotes tight junction proteins expression through PKC/MAPK/ATF-2 signaling pathway.tif by Siyu Dai (8298864)

“…Identified potential ATF-2 binding sites on ZO-1 and OCLN promoters. ATF-2 significantly enhanced ZO-1 promoter activity (p < 0.001). …”

<b>Indirect effects of warming via phenology on reproductive success of alpine plants</b> by Tianwu Zhang (13169939)

“…</p><p dir="ltr">3. Warming significantly advanced the start of flowering <a href="" target="_blank">in early-spring flowering</a> (ESF) and <a href="" target="_blank">mid-summer flowering </a>(MSF) plants, while the fruiting period of ESF plants remained stable. …”

Effects of message content condition on outcomes. by Rhyan N. Vereen (10765678)

“…</p><p>Results</p><p>The CI campaign had significantly higher perceived cultural relevance (M = 4.61) than the general audience (M = 3.64) or control (M = 3.66; p’s<0.05) campaigns. …”

DataSheet1_RETRACTED: Ophthalmic Combination of SurR9-C84A and Trichostatin-A Targeting Molecular Pathogenesis of Alkali Burn.DOCX by Kislay Roy (3466256)

“…The cytokine array analysis revealed that NaOH induced expressions of IL-1α and MMP-9, which were found to be significantly downregulated (1.8 and 11.5 fold respectively) by the combinatorial treatment of SurR9-C84A and TSA.…”

Supplementary Material for: Does manual acupuncture improve gastro-esophageal reflux disease symptoms? A trial sequential meta-analysis by figshare admin karger (2628495)

“…However, considering the efficacy of PPI therapy in significantly improving overall symptoms, along with its established safety profile and extensive clinical utilization over the years, we do not recommend manual acupuncture alone as the primary treatment for patients with GERD.…”

Table 2_The impact of long-term trends in continuity of care on the medical expenses of hypertensive patients: based on group-based trajectory model.xlsx by Yanqiu Du (6817550)

“…After adjustment, the low-level maintenance group had significantly higher expenses than the high-level maintenance group (β = 3,049.44 CNY, p < 0.001). …”

Table 1_α-Glycerol monolaurate promotes tight junction proteins expression through PKC/MAPK/ATF-2 signaling pathway.docx by Siyu Dai (8298864)

“…Identified potential ATF-2 binding sites on ZO-1 and OCLN promoters. ATF-2 significantly enhanced ZO-1 promoter activity (p < 0.001). …”

Participant characteristics, N = 502. by Rhyan N. Vereen (10765678)

“…</p><p>Results</p><p>The CI campaign had significantly higher perceived cultural relevance (M = 4.61) than the general audience (M = 3.64) or control (M = 3.66; p’s<0.05) campaigns. …”

Data Sheet 1_Role of memantine in adult migraine: a systematic review and network meta-analysis to compare memantine with existing migraine preventive medications.docx by Guanglu Li (2315128)

“…</p>Conclusion<p>This study provides prioritisation evidence for memantine in migraine prevention, as memantine can significantly decrease the frequency of migraine attacks, improves response rates, and fair acceptability. …”

Data Sheet 1_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).pdf by Ziqi Han (12840074)

“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”

DataSheet1_Single-cell RNA sequencing uncovers molecular mechanisms of intravenous immunoglobulin plus methylprednisolone in Kawasaki disease: attenuated monocyte-driven inflammati... by Minna Yang (11601433)

“…Additionally, this combination uniquely enhances NK cell cytotoxicity by modulating receptor homeostasis, while significantly upregulating interferon-related genes in CD4+ T cells, CD8+ T cells, and B cells, particularly type I interferons.…”

Sample of study stimuli by content condition. by Rhyan N. Vereen (10765678)

“…</p><p>Results</p><p>The CI campaign had significantly higher perceived cultural relevance (M = 4.61) than the general audience (M = 3.64) or control (M = 3.66; p’s<0.05) campaigns. …”

Table 1_The impact of long-term trends in continuity of care on the medical expenses of hypertensive patients: based on group-based trajectory model.docx by Yanqiu Du (6817550)

“…After adjustment, the low-level maintenance group had significantly higher expenses than the high-level maintenance group (β = 3,049.44 CNY, p < 0.001). …”

Table 3_The impact of long-term trends in continuity of care on the medical expenses of hypertensive patients: based on group-based trajectory model.xlsx by Yanqiu Du (6817550)

“…After adjustment, the low-level maintenance group had significantly higher expenses than the high-level maintenance group (β = 3,049.44 CNY, p < 0.001). …”

Data Sheet 1_The impact of social activity on cardiovascular disease risk among middle-aged and older adults in China: a nationwide cohort study based on the CHARLS database.pdf by Yingting Wu (12215218)

“…</p>Conclusion<p>Social activity is significantly linked to the risk of cardiovascular disease among middle-aged and older adults in China. …”

Image 3_α-Glycerol monolaurate promotes tight junction proteins expression through PKC/MAPK/ATF-2 signaling pathway.tif by Siyu Dai (8298864)

“…Identified potential ATF-2 binding sites on ZO-1 and OCLN promoters. ATF-2 significantly enhanced ZO-1 promoter activity (p < 0.001). …”

Image 1_α-Glycerol monolaurate promotes tight junction proteins expression through PKC/MAPK/ATF-2 signaling pathway.tif by Siyu Dai (8298864)

“…Identified potential ATF-2 binding sites on ZO-1 and OCLN promoters. ATF-2 significantly enhanced ZO-1 promoter activity (p < 0.001). …”

Data Sheet 1_The role of intestinal homeostasis in sevoflurane-induced myelin development and cognitive impairment in neonatal mice.docx by Chang Liu (35901)

“…In the hippocampus and prefrontal cortex, the expression of genes and transcription factors related to oligodendrocyte differentiation and myelin development was significantly affected, and these changes persisted even after the exposure ended. …”

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis by Fateen Ata (12217764)

“…<p>The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. …”