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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
17 decrease » _ decrease (Expand Search), nn decrease (Expand Search), we decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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20381
Interaction of sex hormone receptors and calcium handling proteins in the left ventricle of patients with heart failure
Published 2024“…Compared with the control group, the expression levels of sex hormone receptors and calcium handling proteins in HF patients were significantly decreased. There was co-localization and interaction between protein ERα and Cav1.2, protein AR and SERCA2a, respectively. …”
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20382
Supplementary data: Characterization of medical device randomized controlled trials with adaptive designs
Published 2024“…The average annual number of adaptive RCTs per 1000 clinical trials was the highest (8.55 ± 11.65) during 2005–2010, reduced to 3.33 ± 2.35 during 2011–2016, and significantly decreased to 1.29 ± 0.85 during 2017–2024 (p = 0.011). …”
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20383
Supplementary file 1_Cistanche tubulosa glycosides ameliorate cognitive decline in APP/PS1 mice via modulation of gut microbiota and fatty acid metabolism: insights from multi-omic...
Published 2025“…</p>Results<p>GCT treatment significantly improved spatial memory and reduced the protein levels of Aβ and proinflammatory factors in APP/PS1 mice. …”
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20384
Data Sheet 1_Personalized temporal interference stimulation targeting striatum reduces functional stability and dynamic connectivity variability in the sensorimotor network.docx
Published 2025“…</p>Results<p>(1) Functional stability: TI stimulation significantly decreased functional stability in bilateral SMA regions (predominantly SMA proper, with parts of pre-SMA) compared to Sham and baseline conditions (P < 0.01). (2) Dynamic functional connectivity: TI stimulation reduced dFC variability between the right striatum and left SMA region (predominantly SMA proper, with parts of pre-SMA) compared to baseline (P < 0.01). (3) Safety: No adverse cognitive effects or side effects were observed, with good blinding effectiveness maintained throughout the study.…”
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20385
Supplementary file 3_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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20386
Supplementary file 4_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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20387
Data Sheet 1_Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition.docx
Published 2025“…</p>Results<p>Deg-AZM significantly enhanced intestinal motility in the mice with cisplatin-evoked constipation. …”
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20388
Data Sheet 2_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf
Published 2025“…Introduction<p>Deltamethrin is a pyrethroid insecticide commonly used to kill animal parasites in aquaculture. …”
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20389
Table 1_The CD300c antibody CL7 suppresses tumor growth by regulating the tumor microenvironment in non-small cell lung carcinoma.docx
Published 2025“…Tumor growth was significantly suppressed in the CL7-treated group compared to the PBS control group. …”
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20390
Table 1_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).xls
Published 2025“…Introduction<p>Deltamethrin is a pyrethroid insecticide commonly used to kill animal parasites in aquaculture. …”
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20391
Data Sheet 1_Influence of water temperature on feed intake, appetite control, and energy allocation in Atlantic salmon (Salmo salar) post-smolt.pdf
Published 2025“…Plasma ghrelin (Ghrl) levels decreased significantly at elevated temperature. Temperature negatively affected the ghrl1 expression in the stomach, and the expression dynamics of the orexigenic neuropeptide npya and anorexigenic pomca paralogues in the hypothalamus, which were lower at 15°C. …”
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20392
Image 1_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).tif
Published 2025“…Introduction<p>Deltamethrin is a pyrethroid insecticide commonly used to kill animal parasites in aquaculture. …”
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20393
Negative Activation Volume in Hydrated BaZr<sub>0.8</sub>Y<sub>0.2</sub>O<sub>3−δ</sub> Proton Conductor at Room Temperature (Supporting Information)
Published 2025“…The bulk resistance of the material decreases as the pressure increases, with a decrement ratio from −0.6 to −2.3 % per 60 MPa variation in pressure. …”
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20394
Supplementary file 1_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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20395
Table 1_ADAM8 in macrophages exacerbates sepsis-induced cardiomyopathy by impeding efferocytosis.docx
Published 2025“…Introduction<p>Sepsis-induced cardiomyopathy (SICM) is a life-threatening complication characterized by acute cardiac dysfunction during sepsis., and macrophages play a crucial role in SICM pathogenesis. …”
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20396
Table 1_Microwave ablation triggers OX40L-mediated disruption of TNFRSF4+ Treg immunosuppressive activity.docx
Published 2025“…In vivo, MWA reshaped the tumor microenvironment by significantly increasing the intratumoral CD8+/Treg ratio (P<0.001), indicating a shift toward an anti-tumor inflammatory state. …”
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20397
Data Sheet 3_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf
Published 2025“…Introduction<p>Deltamethrin is a pyrethroid insecticide commonly used to kill animal parasites in aquaculture. …”
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20398
Image 2_13C-CO2 pulse labelling evaluation of water deficit on leaf carbon dynamics and whole plant allocation in fruiting coffee.png
Published 2025“…These were analysed to assess <sup>13</sup>C enrichment in relation to carbon assimilation and leaf carbon changes over time. Water deficit significantly decreased carbon assimilation by 20-52% compared to well-watered plants, especially in young leaves (p< 0.05). …”
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20399
Supplementary file 6_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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20400
Supplementary file 2_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”