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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
17 decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
17 decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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20181
Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf
Published 2025“…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”
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20182
Data Sheet 1_Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae.pdf
Published 2025“…Infections of Galleria mellonella larvae showed a significantly decreased virulence potential of the CPS-deficient mutant.…”
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20183
Image 2_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”
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20184
Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents
Published 2024“…Further mechanistic studies revealed that compound <b>13</b> significantly induced cell apoptosis by increasing the expression levels of cleaved caspase-3 and reducing Bcl-2 proteins through downregulating the EGFR/PI3K/Akt signalling pathway, leading to the inhibition of proliferation in HCT116 and PC9 cells. …”
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20185
Supplementary Material for: A common variant in NID1 gene associated with the prognosis of heart failure
Published 2025“…Western blot analysis demonstrated that the protein level of NID1 was significantly higher in the rs3738530-T allele compared to the A allele (P < 0.05). …”
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20186
Data Sheet 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.pdf
Published 2024“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”
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20187
Data Sheet 12_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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20188
Image 14_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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20189
Dust particle flow trace diagram.
Published 2025“…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …”
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20190
Adverse events in patients with castration-resistant prostate cancer treated with ra-223: a retrospective pharmacovigilance study
Published 2024“…Four sequential analysis strategies were employed to assess the significance of these AEs.</p> <p>In total, 4,228 Ra-223-related AE reports were identified in the FAERS database. …”
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20191
Table 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin...
Published 2025“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”
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20192
Vitreous Olink Proteomics Uncovers Novel Inflammatory Proteins in Patients with Proliferative Diabetic Retinopathy
Published 2025“…Functional studies demonstrated that the conditioned medium from HG-exposed MG significantly enhanced endothelial cell proliferation, migration, and tube formation. …”
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20193
Image 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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20194
Discrete phase parameter setting.
Published 2025“…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …”
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20195
Data Sheet 3_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.csv
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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20196
Table 1_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”
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20197
Table 1_Case report: Treatment of severe phorate poisoning.xlsx
Published 2025“…In the follow-up treatment, the concentration of five metabolites gradually decreased. The concentration of the phorate sulfoxide and phorate sulfone rebounded with the suspension of HP, but that of the other metabolites did not rebound. …”
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20198
Bgh/GelMA/CMCS hydrogel with bone MSC-EVs for lunate defect repair
Published 2025“…In vivo, the M1/M2 ratio and inflammatory factors decreased significantly one-week post-implantation, while CD31 and VEGF-positive cells increased at four weeks, and BMP2 and OPN-positive cells at eight weeks. …”
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20199
Disruption of Astrocyte Communication by Carbenoxolone During Shockwave-Induced Stress
Published 2025“…Peak calcium intensity was significantly reduced at 100 µM CBX, and both rise and fall rates of calcium signals decreased with increasing CBX concentration. …”
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20200
Supplementary file 1_Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.docx
Published 2025“…Lipid metabolism was significantly altered in moderate-altitude athletes, including pathways such as linolenic and linoleic acid, sphingolipid, and arachidonic acid, as well as processes involving the transfer of acetyl groups into mitochondria and fatty acid biosynthesis. …”