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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
17 decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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21281
Table 2_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease...
Published 2025“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”
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21282
Data Sheet 4_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf
Published 2025“…YQHX also restored MAMs morphology, decreased mPTP opening and Ca<sup>2+</sup> levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…”
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21283
Supplementary file 1_Metal ion-enhanced photosynthetic bacteria for bioplastic production from kitchen waste digestate: performance and mechanism.docx
Published 2025“…</p>Conclusion<p>The concentration of 10 mg/L Fe<sup>3+</sup> and 2 mg/L Mn<sup>2+</sup> significantly enhanced PSB biomass and PHB accumulation (p < 0.05). …”
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21284
Image2_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif
Published 2024“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”
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21285
Data Sheet 3_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx
Published 2024“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”
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21286
Data Sheet 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip
Published 2025“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”
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21287
Data Sheet 3_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf
Published 2025“…YQHX also restored MAMs morphology, decreased mPTP opening and Ca<sup>2+</sup> levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…”
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21288
RtcB cooperates with its cofactor Archease to promote axon regeneration.
Published 2025“…(D and E) Compared with <i>RtcB</i><sup><i>1-4B</i></sup> or <i>Archease</i><sup><i>PB</i></sup> heterozygotes, axon regeneration is significantly decreased in <i>RtcB</i> and <i>Archease</i> transheterozygotes. …”
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21289
Video 1_Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.mp4
Published 2025“…Overexpression of kininogen and exogenous bradykinin administration significantly increased pentylenetetrazole-induced seizure susceptibility in mice. …”
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21290
Table 5_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls
Published 2025“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”
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21291
Table 1_Assessment of various salt water stresses with mineralization on plant growth and antioxidants activity to regulate oxidative stress and ROS scavenging of halophyte ice pla...
Published 2025“…The results indicated that the T6 treatment (saline-alkali solution of 30 g/L) strongly decreased the plant height, stem thickness, leaf area and SPAD value of ice plants, and obviously suppressed the shoot and root biomass with the increase in salinity. …”
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21292
Image 5_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff
Published 2025“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”
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21293
<b>Targeted Inhibition of Tumor-Intrinsic SIRPα Improve anti-PD-1 Resistance by Enhancing T Cell Immunity and Inhibits</b><b> Tumor </b><b>Proliferation in Esophageal Cancer: Thera...
Published 2025“…Apoptosis of PBMC and Jurkat T cell were significantly decreased cocultured with SIRPA knockdown esophageal cells. …”
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21294
Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis
Published 2025“…Furthermore, LPS and FeSO<sub>4</sub> significantly increased the expression of IL-6, TNF-α, and phosphorylation of p38, pMAPK, and pNFkB in the cells. …”
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21295
Image2_The correlation between Diabetes and age-related degeneration and the static and dynamic 3D mechanical distribution of different plantar regions.jpeg
Published 2024“…</p>Conclusions<p>Our findings indicate that both static and dynamic plantar pressures and shear forces are significantly greater in diabetic patients and HO individuals compared to HY adults. …”
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21296
Table3_The correlation between Diabetes and age-related degeneration and the static and dynamic 3D mechanical distribution of different plantar regions.docx
Published 2024“…</p>Conclusions<p>Our findings indicate that both static and dynamic plantar pressures and shear forces are significantly greater in diabetic patients and HO individuals compared to HY adults. …”
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21297
Table6_The correlation between Diabetes and age-related degeneration and the static and dynamic 3D mechanical distribution of different plantar regions.docx
Published 2024“…</p>Conclusions<p>Our findings indicate that both static and dynamic plantar pressures and shear forces are significantly greater in diabetic patients and HO individuals compared to HY adults. …”
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21298
Table5_The correlation between Diabetes and age-related degeneration and the static and dynamic 3D mechanical distribution of different plantar regions.docx
Published 2024“…</p>Conclusions<p>Our findings indicate that both static and dynamic plantar pressures and shear forces are significantly greater in diabetic patients and HO individuals compared to HY adults. …”
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21299
Edaravone inhibits neuronal ferroptosis and alleviates acute Central nervous system injury induced by diquat <i>via</i> enhancement of METTL14-mediated m6A methylation of Aldh1l1
Published 2025“…Eda notably attenuated apoptosis, pro-inflammatory cytokines activation, and oxidative stress damage in diquat-induced rats. Eda significantly suppressed apoptosis, mitophagy and ferroptosis after diquat-stimulated PC12 cells. …”
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21300
Image1_The correlation between Diabetes and age-related degeneration and the static and dynamic 3D mechanical distribution of different plantar regions.jpeg
Published 2024“…</p>Conclusions<p>Our findings indicate that both static and dynamic plantar pressures and shear forces are significantly greater in diabetic patients and HO individuals compared to HY adults. …”