Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

<i>Tg</i>ATM1-depleted <i>Toxoplasma</i> are functionally complemented through expression of the <i>Plasmodium</i> or yeast homolog. by Deepti Shrivastava (17715780)

“…Unchanged proteins are displayed in black, while significantly altered proteins are displayed in grey (< 1.5-fold change (FC), local false discovery rate, LFDR < 0.05) or in blue (>1.5-fold increased; LFDR < 0.05) or red (> 1.5-fold decreased; LFDR < 0.05). …”

Downregulation of ATM1 affects iron-sulfur cluster proteins in <i>Toxoplasma</i> and iron levels in <i>Plasmodium</i>. by Deepti Shrivastava (17715780)

“…Unchanged proteins are displayed in black, while significantly altered proteins are displayed in grey (< 1.5-fold change (FC), local false discovery rate, LFDR < 0.05) or in blue (>1.5-fold increased; LFDR < 0.05) or red (> 1.5-fold decreased; LFDR < 0.05). …”

Image 1_The change of bacterial community structure helped Salvia miltiorrhiza alleviate the pressure of drought stress.png by Hai Wang (310051)

“…Inoculated plants exhibited a 3.61-fold increase in biomass compared to the uninoculated controls. …”

pH sensitive lipid polymeric hybrid nanoparticle (LPHNP) of paclitaxel and curcumin for targeted delivery in breast cancer by Hrishikesh Sarma (14827761)

“…MTT-assay studies revealed enhanced cytotoxicity of CUR and PTX as LPHNPs showing IC₅₀ value of free CUR & PTX 480.06 µg/mL decreasing to 282.97 µg/mL for CS-CUR-PTX-LPHNPs. <i>In vivo</i> pharmacokinetic evaluations in rats confirmed significantly improved bioavailability, with a 3.8-fold increase in AUC for CUR and a 6.6-fold increase for PTX. …”

QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells by Neha Laxane (19851759)

“…</p> <p>Roughly 30-fold increase in cellular uptake was obtained as compared with free drugs.…”

Supplementary file 1_Impacts of Bacillus-based biotics and an enzyme cocktail on growth performance, immunity, and gut pathogenic microorganisms of nursery pigs under commercial co... by Seong-Min Koo (21788807)

“…In terms of immunity, B treatment increased immunoglobulin M levels, while D treatment increased immunoglobulin A levels during weeks 0–2 (p < 0.01). …”

Table1_Adverse event signal mining and severe adverse event influencing factor analysis of Lumateperone based on FAERS database.docx by Yanjing Zhang (401134)

“…Specifically, female patients had a 1.811-fold increased risk compared with male patients (OR = 1.811 [1.302, 2.519], p = 0.000), while patients with bipolar II disorder had a 1.695-fold increased risk compared with patients diagnosed with bipolar disorder (OR = 1.695 [1.320, 2.178], p = 0.000). …”

Table 1_CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway.docx by Liubing Hou (10888140)

“…Background<p>Radioresistance poses a major therapeutic challenge in ESCC, significantly impacting patient prognosis. …”

Presentation 1_Global patterns of change in the burden of malnutrition in older adults from 1990 to 2021 and the forecast for the next 25 years.pdf by Le Li (356426)

“…</p>Results<p>In 2021, over 97.60 million cases of malnutrition among the elderly were reported globally, a 1.2-fold increase from 44.36 million cases in 1990. …”

Data Sheet 1_Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.xlsx by Gabriela Gonzales (19756103)

“…Differential abundance analysis demonstrated significant positive log fold changes in genera such as Bergeriella, Peptostreptococcus, and Bacteriodes with thermal injury over time. …”

Table 1_Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.xlsx by Gabriela Gonzales (19756103)

“…Differential abundance analysis demonstrated significant positive log fold changes in genera such as Bergeriella, Peptostreptococcus, and Bacteriodes with thermal injury over time. …”

Data Sheet 1_Variation and spread of resistomes in swine manure, manure slurries, and long-term manure-fertilized soils.docx by Lei Jin (120473)

“…</p>Results<p>Anaerobic digestion reduced antibiotic and metal (except ciprofloxacin) content and risks in manure, but had limited effects on total ARG abundance, while increasing ARG network modularity. High-risk ARG abundance significantly increased from 404.7 in manure to 843.2 in slurries, with health-risk scores rising 1.88-fold during anaerobic digestion. …”

Supplementary file 3_Impacts of Bacillus-based biotics and an enzyme cocktail on growth performance, immunity, and gut pathogenic microorganisms of nursery pigs under commercial co... by Seong-Min Koo (21788807)

“…In terms of immunity, B treatment increased immunoglobulin M levels, while D treatment increased immunoglobulin A levels during weeks 0–2 (p < 0.01). …”

Supplementary file 2_Impacts of Bacillus-based biotics and an enzyme cocktail on growth performance, immunity, and gut pathogenic microorganisms of nursery pigs under commercial co... by Seong-Min Koo (21788807)

“…In terms of immunity, B treatment increased immunoglobulin M levels, while D treatment increased immunoglobulin A levels during weeks 0–2 (p < 0.01). …”

PRMT5 isoforms during zebrafish developmental stages by Zain Zakaria (20354028)

“…Western blot analysis revealed that Prmt5 protein expression can be detected as early as 6 hrs post-fertilization (hpf), gradually increases 9.3-fold by 18 hpf, and decreases 2 to 3-fold between 24 and 72 hpf.…”

Study group background characteristics. by Zicheng Hu (3825313)

“…Minor, though not significant, increases were present in the <b><i>RxNFL+</i></b> group. …”

DataSheet1_Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters.PDF by Safaa Yehia Eid (17768736)

“…In MCF-7/ADR and MDA-MB-231/ADR cells, COP (31 μM) enhanced DOX cytotoxicity with CI (0.77 and 0.75), RR (2.58 and 3.33), and IB suggesting synergism. COP significantly inhibits ABCT function in resistant BC cell lines, increases Rho123 accumulation, and decreases efflux more than VER; 2.1 and 1.2-fold, respectively. …”