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20021
Supplementary file 6_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR<sup>+</sup> Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”
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20022
Supplementary file 1_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR<sup>+</sup> Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”
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20023
Table 1_Cross-education: motor unit adaptations mediate the strength increase in non-trained muscles following 8 weeks of unilateral resistance training.xlsx
Published 2025“…These gains were accompanied by significant decreases in motor unit recruitment thresholds (p < 0.01) and higher net discharge rate (i.e., gain in discharge rate from recruitment to peak) following intervention (p < 0.05). …”
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20024
Data Sheet 1_Temperature influences mood: evidence from 11 years of Baidu index data in Chinese provincial capitals.csv
Published 2025“…Conversely, a 1°C increase in DTR led to decreases of 30.35%, 31.19%, and 15.41% in these indices (p < 0.05). …”
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20025
Data Sheet 1_Self-esteem and peer pressure susceptibility mediating the link between maternal behavior and adolescent risk behaviors.pdf
Published 2025“…Although parental influence decreases and peer influence increases during this time, parental behavior still plays a significant role. …”
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20026
Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure
Published 2024“…The Pb-exposed male brain exhibited increased <i>Taok3</i> expression (<i>p</i> < 0.05) and decreased DNA methylation (FDR < 0.01). The results demonstrate that perinatal Pb exposure stably influences longitudinal piRNA expression in a tissue- and sex-specific manner, potentially via DNA methylation-directed mechanisms.…”
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20027
Table 1_Coptis japonica Makino ethanol extracts attenuates cancer cachexia induced muscle and fat wasting through inhibition of the STAT3 signaling pathway.docx
Published 2025“…This research aimed to explore the potential of CJM extracts (CJME) in mitigating cancer cachexia in both myotubes treated with CT26 conditioned medium (CM) and in a CT26-induced cancer cachexia mouse model. Our results demonstrated that CJME significantly decreased the mRNA and protein levels of muscle-specific E3 ubiquitin ligases Atrogin-1 and MuRF1 in myotubes exposed to CT26 CM. …”
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20028
Supplementary file 3_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR<sup>+</sup> Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”
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20029
Supplementary file 2_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR<sup>+</sup> Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”
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20030
Table 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx
Published 2025“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”
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20031
Data Sheet 1_An exploratory study on the metagenomic and proteomic characterization of hypothyroidism in the first half of pregnancy and correlation with Th1/Th2 balance.docx
Published 2025“…</p>Conclusion<p>Increased P. vulgatus and B. fragilis, decreased DGKK and S10A8 proteins, and a left shift in the Th1/Th2 balance in patients with hypothyroidism in the first half of pregnancy may be associated with the development of the disease.…”
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20032
Table 3_Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials.pdf
Published 2025“…Protein adsorption to the membrane types did not vary to a large extent, but a decreased flow rate significantly reduced the differences in protein adsorption between both membrane types and led to the adhesion of significantly higher amounts of inhibitory proteins C1INH and α1-AT. …”
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20033
Table 2_Role of miR-144-5p in modulating lipid metabolism and potentially alleviating obesity via the PGC-1α/AMPK pathway.xlsx
Published 2025“…Introduction<p>MiR-144-5p is differentially expressed in plasma exosomes from Bactrian camels of varying body sizes, with GO and KEGG analyses indicating that its target genes play crucial roles in lipid metabolism. PGC-1α, confirmed as a key target through RNA pull-down and dual-luciferase reporter assays, is a significant regulator of this process. …”
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20034
Image 2_An integrated immunoinformatic approach to design a novel multiepitope chimeric vaccine against Mycoplasma phocimorsus as a causal agent of bloodstream infections.jpeg
Published 2025“…Introduction<p>Mycoplasma phocimorsus is increasingly recognized as an emerging human pathogen, despite its primary association with marine mammals. …”
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20035
Table 1_Mechanistic exploration of obesity-related indicators and motor cognitive risk syndrome: a mediated effect based on C-reactive protein triglyceride glucose index.xlsx
Published 2025“…</p>Results<p>BMI, WC, WHtR, and BRI all significantly increased the risk of MCR. Threshold analysis revealed a nonlinear BRI-MCR association (inflection point = 2.45, P = 0.041), whereas the association with WHtR was linear (P = 0.069). …”
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20036
Table 1_Interval walking training as a potential contributor to motor function improvement in adults with type 2 diabetes mellitus: a retrospective analysis.docx
Published 2025“…Changes in motor function were assessed using a motor function analyzer, and factors associated with these changes were identified using multiple linear regression analysis.</p>Results<p>Among 51 adults with T2DM (including 24 aged ≥65 years), IWT significantly improved F/w (median [IQR]: 1.32 [1.26–1.36] to 1.32 [1.27–1.38] kgf/kg, p = 0.038), RFD/w (9.50 [8.03–13.12] to 10.2 [9.43–11.00] kgf/s/kg, p = 0.001), and BIS (52.0 [44.5–55.0] to 54.0 [48.0–56.0], p = 0.020). …”
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20037
Table_1_Association of dietary inflammatory index with sarcopenia in patients with Metabolic dysfunction-associated fatty liver disease: a cross-sectional study.DOCX
Published 2024“…Background<p>Sarcopenia is a common complication of fatty liver, and sarcopenia increases the risk of advanced liver fibrosis in patients with Metabolic dysfunction-associated fatty liver disease (MAFLD). …”
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20038
A cross-sectional study on Prediction of Stature from Arm and Forearm Length in the Age Group of 18 to 25 Years of Addis Ababa Population, Addis Ababa, Ethiopia, December 2023
Published 2025“…Data entered and analyzed with SPSS version 23. A simple linear regression model was computed to estimate stature from arm and forearm length.…”
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20039
Data Sheet 1_Optimizing drought tolerance in cassava through genomic selection.docx
Published 2024“…This study aimed to identify cassava clones with tolerance to water stress by employing truncated selection and selection based on genomic values for population improvement and genotype evaluation per se. The Best Linear Unbiased Predictions (BLUPs), Genomic Estimated Breeding Values (GEBVs), and Genomic Estimated Genotypic Values (GETGVs) were obtained based on different prediction models via genomic selection. …”
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20040
Image 1_Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and metabolic dysfunction-associated steatotic liver disease....
Published 2025“…Logistic regression analyses revealed a significant positive correlation between NHHR and MASLD. …”