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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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13481
Image 4_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem...
Published 2025“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”
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13482
Image 2_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem...
Published 2025“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”
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13483
Table 1_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem...
Published 2025“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”
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13484
Table 1_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021.docx...
Published 2025“…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …”
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13485
Image 3_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem...
Published 2025“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”
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13486
Image 1_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem...
Published 2025“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”
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13487
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13488
Data Sheet 1_Case Report: Metabolic alterations and cholesterol esterification in a low-grade diffuse astrocytoma patient who progressed to glioblastoma at recurrence.docx
Published 2025“…</p>Case presentation<p>A 66-year-old female patient underwent surgical resection of a WHO Grade 2 diffuse astrocytoma in April 2018. …”
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13489
Table 1_Unpacking the cost implications of diagnosis-related groups reform for lumbar disc herniation patients in Chinese medicine: a closer look at evidence from China.xls
Published 2025“…Objectives<p>Lumbar disc herniation (LDH) presents a significant economic burden globally, worsening in China due to an aging population. …”
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13490
Data_Sheet_1_Association of systemic immune-inflammation index with malnutrition among Chinese hospitalized patients: a nationwide, multicenter, cross-sectional study.docx
Published 2024“…Q<sub>1</sub>, OR = 1.83, 95%CI: 1.67–2.00). However, a significant reduction in prevalence was observed when SII was in the second quartile (Q<sub>2</sub> vs. …”
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13491
Image 2_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg
Published 2025“…BALF samples of ALI mice displayed high soluble PDL-1 and reduced soluble 1,25(OH)<sub>2</sub>D levels compared to naïve mice. 1,25(OH)<sub>2</sub>D treatment alongside OA led to a significant fourfold increase in the CD107a and NKp46 expressions to levels higher than the mice treated with the vehicle. …”
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13492
Image 3_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg
Published 2025“…BALF samples of ALI mice displayed high soluble PDL-1 and reduced soluble 1,25(OH)<sub>2</sub>D levels compared to naïve mice. 1,25(OH)<sub>2</sub>D treatment alongside OA led to a significant fourfold increase in the CD107a and NKp46 expressions to levels higher than the mice treated with the vehicle. …”
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13493
Table 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.docx
Published 2025“…BALF samples of ALI mice displayed high soluble PDL-1 and reduced soluble 1,25(OH)<sub>2</sub>D levels compared to naïve mice. 1,25(OH)<sub>2</sub>D treatment alongside OA led to a significant fourfold increase in the CD107a and NKp46 expressions to levels higher than the mice treated with the vehicle. …”
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13494
Image 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpg
Published 2025“…BALF samples of ALI mice displayed high soluble PDL-1 and reduced soluble 1,25(OH)<sub>2</sub>D levels compared to naïve mice. 1,25(OH)<sub>2</sub>D treatment alongside OA led to a significant fourfold increase in the CD107a and NKp46 expressions to levels higher than the mice treated with the vehicle. …”
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13495
Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls...
Published 2024“…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …”
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13496
Development and validation of an ultra-performance liquid chromatography with tandem mass spectrometry method for determination of soluble repulsive guidance molecule A in human se...
Published 2024“…</p> <p>In CSF from patients with MCI and those with AD, total soluble RGMa was significantly decreasing to a median of 22.6 and 21.4 ng/ml, respectively.…”
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13497
Table 1_Genetic diversity and antibiotic resistance of Mycobacterium bovis in bovines in the Delta area of Egypt.docx
Published 2025“…Introduction<p>Mycobacterium bovis (M. bovis) causes significant financial harm to the cattle industry through decreased productivity and trade limitations, while also posing a risk to human health through zoonotic transmission, which is primarily from unpasteurized milk or close animal contact.…”
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13498
Table 1_Differences in the dynamic balance function of healthy elementary school students and university students observed with and without the use of a sensor-integrated gamificat...
Published 2025“…Measurements were performed using a normal Y-Balance test and a Y-Balance test with a sensor game to encourage slow movements. …”
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13499
Table 1_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Marine...
Published 2025“…Climate change poses a significant threat to this dynamic, as C. finmarchicus populations are at the southern edge of their subarctic distribution and are vulnerable to warming waters and changing oceanographic conditions. …”
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13500
Table 2_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Marine...
Published 2025“…Climate change poses a significant threat to this dynamic, as C. finmarchicus populations are at the southern edge of their subarctic distribution and are vulnerable to warming waters and changing oceanographic conditions. …”