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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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13761
Data Sheet 1_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.pdf
Published 2024“…<p>Ferroptosis is a regulated form of cell death characterized by iron-dependent lipid peroxidation of polyunsaturated fatty acids (PUFAs). …”
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13762
Data Sheet 1_Tumor-associated MerTK promotes a pro-inflammatory microenvironment and enhances immune checkpoint inhibitor response in triple-negative breast cancer.docx
Published 2025“…</p>Results<p>Overexpression of MerTK in TNBC syngeneic mouse models leads to a marked delay in tumor growth, coupled with significant increases in anti-tumor M1 macrophage, CD4+ T cell, active CD8+ T cell, active NK cell, and NKT cell populations. …”
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13763
Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca...
Published 2024“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”
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13764
Data Sheet 1_Curcumin supplementation accelerates high-altitude acclimatization, prevents polycythemia and modulates gut microbiota in male Han population: a randomized controlled...
Published 2025“…Furthermore, the score of AMS in the curcumin group were lower than those in the placebo group at T<sub>3</sub>, although with no significant difference. Gut microbiota analysis indicated that curcumin significantly increased the abundance of butyrate-producing bacteria Roseburia, Lachnospira, and Sellimonas while decreasing the abundance of Alistipes and Escherichia at high-altitude environments. …”
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13765
DataSheet2_Fibroblasts modulate epithelial cell behavior within the proliferative niche and differentiated cell zone within a human colonic crypt model.xlsx
Published 2024“…The crypts possessed a basal stem cell niche populated with proliferative cells and a differentiated, nondividing cell zone at the luminal crypt end. …”
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13766
DataSheet1_Fibroblasts modulate epithelial cell behavior within the proliferative niche and differentiated cell zone within a human colonic crypt model.docx
Published 2024“…The crypts possessed a basal stem cell niche populated with proliferative cells and a differentiated, nondividing cell zone at the luminal crypt end. …”
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13767
Table 1_Association of serum chemokine (C–C motif) 21 and receptor (C–C motif) 7 with Hashimoto’s thyroiditis——a preliminary clinical investigation.docx
Published 2025“…</p>Results<p>Compared with the healthy control group, the Hashimoto’s thyroiditis group had significantly increased serum CCL21 [154.92 (147.01, 165.34) vs 123.74 (118.02,129.22), p<0.001] and CCR7 [19.15 (18.19, 19.71) vs 16.47 (15.88, 17.14), p<0.001], decreased free triiodothyronine, and increased thyroid stimulating hormone, TgAb, and TPOAb. …”
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13768
Data Sheet 1_Association between remnant cholesterol levels and reversion to normoglycemia from prediabetes: a 5-year longitudinal cohort study of Chinese non-obese adults.docx
Published 2025“…Specifically, as RC quartiles increase, the probability of reverting to normoglycemia significantly decreases, with participants in the highest quartile having a 51% lower likelihood of recovery compared to those in the lowest quartile. …”
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13769
Image 1_Double-lumen tubes verus single-lumen tube in patients undergoing minimally invasive cardiac surgery: a randomised, controlled clinical trial.pdf
Published 2025“…</p>Conclusions<p>Two-lung ventilation with single-lumen tube is easy to perform, significantly increases oxygenation, and decreases the incidence of postoperative complications and airway injuries. …”
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13770
Data Sheet 1_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx
Published 2025“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. …”
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13771
Table 1_Associations between systemic inflammatory indices and the risk of renal function decline in patients with type 2 diabetes mellitus: a retrospective cohort study.docx
Published 2025“…The ROC curves showed that the SIRI was better than other two indices at predicting renal function decline.</p>Conclusion<p>A significantly positive association was shown between systemic inflammatory indices and the risk of renal function decline in T2DM patients. …”
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13772
Data Sheet 2_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx
Published 2025“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. …”
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13773
Supplementary file 1_IGF-1 secreted by mesenchymal stem cells affects the function of lymphatic endothelial progenitor cells: a potential strategy for the treatment of lymphedema.d...
Published 2025“…These results suggest that MSCs significantly promote the proliferation of LEPCs through the activation of the PI3K/Akt/mTOR pathway in LEPCs by secreting IGF-1, and that IGF-1 also inhibits apoptosis and regulates cell metabolism. …”
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13774
Data Sheet 1_Psychological and cultural correlates of illness conception and menopausal symptoms: a cross-sectional and longitudinal comparative study of Mosuo, Yi, and Han women.p...
Published 2025“…Both the menopausal symptoms and the scores for concerns and fears about illness among Mosuo women significantly decreased in 2020 compared to 2012 (p = 0.040, p = 0.010).…”
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13775
Image 2_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff
Published 2025“…[<sup>18</sup>F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”
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13776
Image 4_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff
Published 2025“…[<sup>18</sup>F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”
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13777
Table 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.docx
Published 2025“…[<sup>18</sup>F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”
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13778
Data_Sheet_1_Long-term phenobarbital treatment is effective in working-age patients with epilepsy in rural Northeast China: a 10-year follow-up study.docx
Published 2024“…The most commonly reported AEs were drowsiness (43.3%), dizziness (25.0%), and headaches (17.0%), most of which were mild and decreased over time. Age at enrollment was the only factor influencing withdrawal (hazard ratio = 0.984, 95% CI: 0.973–0.996, p = 0.010), with a substantial number of patients who withdrew (32.6%) relocating for work. …”
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13779
Image 3_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff
Published 2025“…[<sup>18</sup>F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”
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13780
Supplementary file 1_Association between changes in corrected anion gap and mortality among critically ill patients during ICU stay: a multicenter observational study.doc
Published 2025“…When analyzed categorically, the ΔcAG still exhibited a significant risk gradient across quartiles.</p>Conclusion<p>Further elevated cAG after ICU admission demonstrates a robust association with an increased mortality risk in critically ill patients. …”