Data Sheet 1_Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis.z... by Peng Ren (337555)

“…Metabolic pathway enrichment analysis showed that differential lipid PEs were significantly enriched in the iron death pathway, and our further in vitro cellular experiments showed that baicalin could inhibit Erastin-induced Ferroptosis in the hippocampal neuronal cell line HT-22 by promoting the expression of SLC7A11, GSH, and GPX4, inhibiting the expression of ACSL4, and decreasing the cellular ROS.…”

<b>White</b><b>-shouldered starlings </b><b>prefer</b><b> nest boxes with smaller entrance to </b><b>avoid</b><b> nest usurpation</b> by Yuran Liu (19453828)

“…However, due to large areas of land being utilized for aquaculture and livestock farming, the availability of natural tree cavities in the area has significantly decreased. This scarcity of natural nest sites provided ideal experimental conditions for attracting birds using artificial nest boxes (see Liu et al., 2023). …”

Table_1_Hyperthyroidism, hypothyroidism, thyroid stimulating hormone, and dementia risk: results from the NHANES 2011–2012 and Mendelian randomization analysis.DOCX by Xixi Sheng (19932165)

“…</p>Conclusion<p>This study provides evidence of a nonlinear relationship between TSH and FT4 concentrations and cognitive function, with hyperthyroidism decreasing the risk of dementia and VaD, hypothyroidism increasing the risk of dementia and VaD, and elevated serum TSH concentrations increasing the risk of AD. …”

Database of the impact of temperature on development of Aedes aegypti and Aedes albopictus in Cambodia by Bros Doeurk (21163097)

“…The experiment was conducted in a climatic chamber with temperatures ranging from 15°C to 40°C, with a 5°C incrementation between each treatment. …”

S1 Raw data - by Dao-Cheng Zhou (20314697)

“…All-cause and CVD mortality gradually decreased with increasing ideal LE8 metrics. LE8 was not significantly associated with cancer mortality. …”

Figure 7 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6B KO decreases tumor growth. <b>A,</b> Colony formation assay of KDM6B KO cells (sgRNA#1 and sgRNA#2) compared with parental and sgCTRL A-673 cells. …”

Supplementary file 1_Effects of human urine application on soil physicochemical properties, microbial communities, and enzymatic activities.docx by Guangquan Yu (21630101)

“…<p>Human urine (HU) is rich in nutrients necessary for plant growth, and recycling HU as fertilizer has multiple positive impacts, such as enhancing agricultural sustainability, reducing wastewater pollution, and decreasing reliance on chemical fertilizers, so it is of great significance to explore the effects of urine agricultural utilization on soil environment. …”

Proteomic analysis for busulfan-induced spermatogenesis disorder by Ke Hu (84619)

“…Western blotting revealed that LDHAL6B protein significantly increased at 10 days, decreased from 20 to 60 days, and then gradually elevated from 70 to 80 days after busulfan treatment.…”

Full name and abbreviation. by Yuanqiang Lv (20623742)

“…</p><p>Results and conclusion</p><p>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group’s SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”

The animal experimental protocol. by Yuanqiang Lv (20623742)

“…</p><p>Results and conclusion</p><p>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group’s SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”

Supplementary Material for: The impact of left ventricular structure and function on mortality in patients with aortic valve infective endocarditis treated with aortic valve replac... by figshare admin karger (2628495)

“…The mean LVEF was 54±11% preoperatively, decreasing to 51±11% postoperatively. The mean baseline LVEDd was 5.8±0.9 cm in males and 5.0±0.9 cm in females (p<0.001), decreasing to 5.2±0.9 cm in males and 4.7±0.6 cm in females after surgery (p=0.006). …”

Figure 2 from Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in <i>EGFR</i>- and <i>KRAS</i>-Mutant Lung Cancer by Xiaoxiao Sun (20589448)

“…<p>PRMT1 knockdown decreases persistence in STAT1-high <i>EGFR</i>^<i>mut</i> and <i>KRAS</i>^<i>G12C</i> lung cancer cell lines. …”

Experiences communicating in noise with aphasia (Harmon et al., 2024) by Tyson G. Harmon (11450904)

“…</p><p dir="ltr"><b>Results: </b>Quantitative findings showed that people with aphasia reported significantly greater perceived effort and stress than controls. …”

Data Sheet 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.docx by Jingjing Chen (293564)

“…Background<p>Preeclampsia, a hypertensive disorder during pregnancy affecting 2-8% of pregnancies globally, remains a leading cause of maternal and fetal morbidity. …”

Table1_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... by Hongbo Cheng (2848235)

“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”

Table1_Sucrose synthase gene family in common bean during pod filling subjected to moisture restriction.docx by Norma Cecilia Morales-Elias (20446292)

“….), leaf photosynthesis is significantly reduced under drought conditions. Previous studies have shown that some drought-tolerant cultivars use the pod walls to compensate the decreased photosynthesis rate in leaves by acting as temporary reservoirs of carbohydrates to support seed filling. …”

Table 2_Building radiomics models based on ACR TI-RADS combining clinical features for discriminating benign and malignant thyroid nodules.docx by Xingxing Chen (1569277)

“…Purpose<p>The aim of this study was to establish and validate a radiomics model combining the American College of Radiology Thyroid Imaging, Reporting and Data System (ACR TI-RADS) and clinical features and to build a nomogram that could be utilized to enhance the diagnostic performance of malignant thyroid nodules.…”

Image 1_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c... by Khalidah Ibraheem (9525220)

“…Optimal cooling at 18°C rescued cell viability, significantly (p < 0.001) restored HF proliferation (42% Ki-67+ cells) and pigmentation, suppressed apoptosis (10% TUNEL+ cells), restored anagen (∼70%) and induced a 2-3-fold increase in hair shaft elongation (p < 0.001), whereas cooling at 26°C was only partially effective. …”

Table2_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... by Hongbo Cheng (2848235)

“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”

Table 1_Building radiomics models based on ACR TI-RADS combining clinical features for discriminating benign and malignant thyroid nodules.docx by Xingxing Chen (1569277)

“…Purpose<p>The aim of this study was to establish and validate a radiomics model combining the American College of Radiology Thyroid Imaging, Reporting and Data System (ACR TI-RADS) and clinical features and to build a nomogram that could be utilized to enhance the diagnostic performance of malignant thyroid nodules.…”