Image 3_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif حسب Jorgo Lika (21189020)

"…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …"

Supplementary Materials - Figure حسب Shaojie Zhang (20807333)

"…<p dir="ltr">Exposure to hypobaric hypoxia during rapid ascent to high altitudes significantly impacts intestinal barrier function. Goblet cells, as one of the primary cell types in the intestinal mucosa, play a crucial role in maintaining this barrier. …"

Table 2_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.xlsx حسب Yali Han (4676677)

"…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…"

Table 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.xls حسب Linjie Peng (12553717)

"…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …"

Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx حسب Mattia Dalle Nogare (22696022)

"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"

Data Sheet 1_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.csv حسب Jiashuo Li (7865036)

"…Background<p>The tumor microenvironment (TME) plays a critical role in the development, progression, and clinical outcomes of hepatocellular carcinoma (HCC). …"

Dynamic visualization of DNA methylation in cell cycle genes during iPSC cardiac differentiation حسب Ning Li (45258)

"…<p>Existing analyses with conventional assays have generated significant insights into static states of DNA methylation but were unable to visualize the dynamics of epigenetic regulation.…"

Multifaceted roles of NADPH oxidases in the growth and pathogenicity of <i>Beauveria bassiana</i> حسب Shengan Zhu (19817727)

"…Knockout strains of single BbNoxA, BbNoxB, BbNoxR, and double BbNoxA and BbNoxB were constructed via homologous recombination, and their phenotypic characteristics were examined. …"

Table 2_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.xlsx حسب Giuseppe G. F. Leite (18186056)

"…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …"

Aquaporin and red cell O2 permeability حسب S. Al-Samir (20965502)

"…We find that at 7°/10°C lack of AQP1 in the red cell membrane causes significant reductions of PO2, by 20% in human and by 37% in mouse red cells. …"

Image 1_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg حسب Jiashuo Li (7865036)

"…Background<p>The tumor microenvironment (TME) plays a critical role in the development, progression, and clinical outcomes of hepatocellular carcinoma (HCC). …"

Data Sheet 1_The impact of landscape patterns on surface runoff in the central urban area of Chengdu.docx حسب Ying Kang (2503126)

"…When the proportions of farmland and forestland were low, their effectiveness in reducing runoff decreased with increasing rainfall intensity. Similarly, the impact of impervious surfaces also diminished with increasing rainfall intensity. ④ The SSRLI demonstrated good applicability in predicting changes in surface runoff, showing a significant positive correlation with runoff depth. …"

Image 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf حسب Maxim Sorokin (4379848)

"…The known fusion KANSL1-ARL17A/B occurred with a high frequency in 69% of the patients. …"

Workflow of the study. حسب Hongliang Chen (538815)

"…<div><p>Immune dysregulation is a pathogenic factor in ulcerative colitis (UC), in which mitochondrial involvement is increasingly recognized. …"

Data Sheet 1_From psychological wellbeing to distress: the role of psychological counseling interventions in university students.pdf حسب Francesco Craig (8214780)

"…Post-intervention, psychological distress decreased significantly (p < 0.001), with 56.7% of students falling over the clinical distress cut-off at T1 compared to 84.4% at T0. …"

Scaling analyses and morphometrics of <i>Ginkgo biloba</i> seeds حسب Wen Gu (129075)

"…When seeds were grouped by the ellipsoid index (EI = <i>V</i>/<i>V</i>_E), the scaling exponent of <i>V</i> vs. <i>M</i> decreased from values significantly greater than one to values less than one as EI increased. …"

Spatial variation and clgassification of anthropogenic soils formed by long-term “<i>Dorotsuke”</i> soil-dressing in Andosols of the Omiya Upland along the Arakawa River, Japan حسب Shokichi Wakabayashi (3872428)

"…The two anthropogenic horizons exceeded 50 cm in thickness with different soil textures, while one of the other two showed significant mixing with Andosol. The profiles exhibited a vertical attenuation of andic characteristics, including increased bulk density, decreased short-range-order mineral content, and reduced phosphate retention, from the buried Andosol up to the topsoil. …"

Data Sheet 1_Analysis of temporal and spatial changes in the global burden of hypertensive heart disease based on data from the Global Burden of Disease study database and future p... حسب Guoliang Gao (2910503)

"…The incidence in females was marginally greater than that in males, yet there were comparable decreases in deaths and DALYs for both sexes. There was a notable increase in prevalence in regions with high SDIs, whereas areas with low SDIs experienced greater disease burdens. …"

Presentation 1_Genomic analysis, culturing optimization, and characterization of Escherichia bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce.... حسب Mustafa Yesil (20403140)

"…Phage titers remained fairly unchanged throughout a 24-month storage at 4°C. Incubation for 30 min at 4°C−47°C or pH 4–11 had no significant detrimental effect (p > 0.05) on phage infectivity. …"

DataSheet1_IVIG response in pediatric acute-onset neuropsychiatric syndrome correlates with reduction in pro-inflammatory monocytes and neuropsychiatric measures.docx حسب Isaac Melamed (6291590)

"…The fraction of pro-inflammatory monocytes and dendritic cells decreased from pre-IVIG treatment levels. The proportional reductions were not compensated by increases in total white blood cells; pro-inflammatory monocytes post-IVIG were decreased as a proportion of CD14+ myeloid cells and in absolute number.…"