Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets حسب Karl Knipper (15016346)

"…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …"

Raw Data. حسب Hongfei Liu (1396348)

"…COS supplementation significantly increased serum superoxide dismutase activity and jejunal mucosal glutathione peroxidase activity, and significantly decreased serum malondialdehyde level (<i><i>P</i></i> < 0.05). …"

Transcriptomic analysis of AMPK and HZL-1 mutants reveals widespread gene expression differences predominantly in the germ line. حسب Sabih Rashid (5618807)

"…<p><b>A)</b> and <b>B)</b> Bubble plots depicting most enriched GO terms in <i><i>daf-2</i></i>, <i><i>daf-2, aak(0)</i>,</i> and <i><i>aak(0); hzl-1</i></i> transcriptomes, ranked by significance based on p-value. …"

Data Sheet 1_Clinical comparison of radiofrequency ablation and surgical resection in treating pulmonar metastasis of hepatoblastoma.docx حسب Yang Li (7082)

"…</p>Results<p>The average levels of AFP in both the radiofrequency ablation group and the surgical resection group decreased significantly after treatment, with no statistical significance between the groups (P>0.05). …"

Data Sheet 1_Biochar and Bacillus subtilis co-drive dryland soil microbial community and enzyme responses.doc حسب Tao Zheng (146941)

"…</p>Discussion<p>In conclusion, rapeseed straw biochar not only enhances the soil microbial community but also significantly influences soil enzyme activity. This study offers a scientific foundation for utilizing biochar and Bacillus subtilis to improve dryland soil, providing valuable insights for sustainable soil management.…"

The timeline of the experiment. حسب Shadi Nazarizadeh (20108029)

"…EEG power in the HINS group decreased significantly compared to other experimental groups (p<0.05). …"

Table 2_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-кB/HI... حسب Yuchan Zhou (10928151)

"…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …"

Data_Sheet_1_miR-124 Alleviates Ischemic Stroke-Induced Neuronal Death by Targeting DAPK1 in Mice.docx حسب Yan Shi (166398)

"…</p>Results<p>In vivo and in vitro results demonstrated that levels of miR-124 were significantly decreased following stroke, whereas changes in death-associated protein kinase 1 (DAPK1) levels exhibited the converse pattern. …"

S1 Raw data - حسب Shadi Nazarizadeh (20108029)

"…EEG power in the HINS group decreased significantly compared to other experimental groups (p<0.05). …"

Data Sheet 1_Assessment of the effect of social media use on medical students’ academic performance: cross-sectional study from Jordan.pdf حسب Hana Taha (4747014)

"…GPA was significantly associated with more time spent on social media (OR: 0.476; 95%CI: 0.278–0.813; p = 0.022). …"

S1 Graphical abstract - حسب Shadi Nazarizadeh (20108029)

"…EEG power in the HINS group decreased significantly compared to other experimental groups (p<0.05). …"

Data Sheet 1_Higher soil nitrous oxide production in landscape depressions linked to soil and hydrological legacy effects.docx حسب Yujia Liu (318262)

"…Depression soils exhibited 3,000- and 4,000-fold higher 16S rRNA and nosZ clade I abundances, respectively, compared to upland soils. Cu addition significantly decreased 16S rRNA abundance, eliminated AOB amoA in upland soils, and slightly reduced the tested gene abundances in depression soils. …"

Data Sheet 2_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-... حسب Yuchan Zhou (10928151)

"…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …"

Table 1_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-кB/HI... حسب Yuchan Zhou (10928151)

"…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …"

Data Sheet 1_Replacement of fish oil with Schizochytrium-derived monoglycerides enriched in docosahexaenoic acid on the growth performance, lipid composition, and intestinal microb... حسب Wei Huang (36889)

"…It was noted that the addition of DHA-MGs significantly decreased the abundance of potentially pathogenic bacteria, manifesting that DHA-MGs could readjust the intestinal microecological balance for intestinal health. …"

Data Sheet 1_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-... حسب Yuchan Zhou (10928151)

"…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …"

Data Sheet 1_Reduced circulating regulatory T cells in primary Sjögren’s syndrome: the contribution of enhanced apoptosis and impaired survival.docx حسب Yanlin Wang (110566)

"…We investigated alterations in the abundance of peripheral Tregs in a large pSS cohort and their implications for patients.…"

Table 3_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-кB/HI... حسب Yuchan Zhou (10928151)

"…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …"

Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx حسب Jikai He (11888466)

"…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"

Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx حسب Jikai He (11888466)

"…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"