Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation by Huang-Ju Tu (630766)

“…Although the development of DYRK1A inhibitors has significantly advanced in recent years, the selectivity of these drugs remains a critical challenge, potentially impeding further progress. …”

Multiplex network of the VSTMBT and <i>nQ</i> example. by Avalon Campbell-Cousins (22110646)

Assessment of calcium events, pERK levels, NMDA receptor expression and extracellular zinc levels in <i>slc13a5</i> mutants. by Deepika Dogra (21072023)

“…<b>(M, M’, N, N’,</b> Q) Quantification of the fluorescence intensity (CTCF) ratios of Palm-ZP1:CellMask Orange in the plasma membrane. <i>5a</i>^{<i>−/−</i>}<i>;5b</i>^{<i>−/−</i>} larvae show a significant decrease in Palm-ZP1:CellMask Orange CTCF ratio in the plasma membrane compared to WTs. …”

The epidemiology and gene mutation characteristics of pyrazinamide-resistant <i>Mycobacterium tuberculosis</i> clinical isolates in Southern China by Nan Wang (21935)

“…This difference in the <i>rpsA</i> mutation rate was statistically significant (<i>P = 0.001</i>, chi-square test). …”

Flow of participants through the study. by Sedighe Esmaeilzadeh (21100668)

“…Furthermore, melatonin significantly decreased sleep latency, exhibiting a large effect size, and contributed to a medium reduction in the use of sleep medications. …”

Demographic Characteristics of Participants. by Sedighe Esmaeilzadeh (21100668)

“…Furthermore, melatonin significantly decreased sleep latency, exhibiting a large effect size, and contributed to a medium reduction in the use of sleep medications. …”

Table 1_IP-10 acts early in CV-A16 infection to induce BBB destruction and promote virus entry into the CNS by increasing TNF-α expression.docx by Yajie Hu (550783)

“…This increase was accompanied by an increase in a series of inflammatory cytokines at different time-points during CV-A16 infection. …”

Baseline analysis, nominal factors. by Hiroaki Yoshikawa (4615801)

“…</p><p>Results</p><p>Our analysis revealed a significantly older age of onset in the 2018 cohort compared to 2006. …”

Minimal dataset for the study. by Hiroaki Yoshikawa (4615801)

“…</p><p>Results</p><p>Our analysis revealed a significantly older age of onset in the 2018 cohort compared to 2006. …”

Baseline analysis, continuous factors. by Hiroaki Yoshikawa (4615801)

“…</p><p>Results</p><p>Our analysis revealed a significantly older age of onset in the 2018 cohort compared to 2006. …”

Multivariable analysis between 2006 and 2018. by Hiroaki Yoshikawa (4615801)

“…</p><p>Results</p><p>Our analysis revealed a significantly older age of onset in the 2018 cohort compared to 2006. …”

CHAMPS pilot Hb dataset. by Jeanie du Toit (20721918)

“…Postmortem testing showed a significant decrease in hemoglobin concentrations compared to antemortem levels. …”

Thermophysical Properties of <i>n</i>‑Hexane under the Influence of Dissolved Hydrogen by Experiments and Equilibrium Molecular Dynamics Simulations by Paul Damp (22538595)

“…With increasing <i>p</i> and <i>x</i>_H2, the measurement results for <i>a</i> and <i>D</i>₁₁ are not significantly affected, except for states approaching the critical point. …”

Deep reinforcement learning agents trained using a curriculum solve navigation tasks with delayed rewards. by William L. Tong (22238845)

S1 Data - by George Mrema (19550255)

“…During this period, the point prevalence of leprosy declined from 0.32 to 0.25 per 10,000 people, and the new case detection rate decreased from 3.1 to 2.4 per 100,000 people; however, these changes were not statistically significant (p > 0.05). …”

A. Representation of the flagellar pocket region in successive stages of flagellar pocket division and new flagellar pocket collar formation. by Marie Zelená (22404144)

Meta-regression of macrolide resistance Mycobacterium isolates over the years; The results of the meta-regression analysis are presented in a scatter plot that shows the trend in t... by Saeid Sadeghi Ghazi Chaki (22582028)

Bistability of equilibrium vaccination levels and the emergence of hysteresis loops in well-mixed populations. by Feng Fu (218124)

A) Expression of known ‘tendon’ transcription factors, B) TGFβ and C) ECM genes measured with RNA-seq. by Heather L. Dingwall (14573796)

“…Expression of ECM related genes are significantly differentially expressed in unique directions during postnatal stages with <i>Dcn</i> and <i>Fmod</i> increasing gradually over time, <i>Col2a1</i>, <i>Col14a1</i>, <i>Col3a1</i>, and <i>Tnmd</i> decreasing over time, <i>Col1a1</i> and <i>Col1a2</i> peak in expression at P14, and <i>Bgn</i> is expressed at higher levels from P0-P14 after which its levels decrease (C). …”

Panels show results of gut microbiota and nutritional intake analyses by provinces. by Jean d’Amour Mutoni (21474045)

“…For panels A and C, each point represents an individual sample. …”