Table 5_Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic n... by Junming Huang (478336)

“…Finally, functional studies were conducted using Small interfering RNA (siRNA)-mediated gene knockdown to predict the biological roles of selected targets.…”

Table 3_Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical development.xlsx by Emma LaNoce (20129628)

“…Mechanistically, RNA-sequencing and immunohistological analysis suggests dysregulated amino acid transport and activation of the integrated stress response in the DTG-treated organoids, and functionally, a small molecule integrated stress response inhibitor (ISRIB) could partially rescue increased expression of proteins related to cell cycle regulation.…”

The Key to Spinal Cord Recovery: Harnessing p21 Inhibition to Boost Neural Stem/Progenitor Cell Proliferation by Tiandi Xiong (11875031)

“…^<i>P21</i><i>siRNA</i>@LP significantly increased the primary NSPC proliferation rate (145.4% on day 1 and 144.7% on day 3, respectively) while maintaining differentiation capacity <i>in vitro</i>. …”

Image 2_Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic n... by Junming Huang (478336)

“…Finally, functional studies were conducted using Small interfering RNA (siRNA)-mediated gene knockdown to predict the biological roles of selected targets.…”

Image 1_Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic n... by Junming Huang (478336)

“…Finally, functional studies were conducted using Small interfering RNA (siRNA)-mediated gene knockdown to predict the biological roles of selected targets.…”

Table 1_Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic n... by Junming Huang (478336)

“…Finally, functional studies were conducted using Small interfering RNA (siRNA)-mediated gene knockdown to predict the biological roles of selected targets.…”

Data Sheet 1_Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical development.docx by Emma LaNoce (20129628)

“…Mechanistically, RNA-sequencing and immunohistological analysis suggests dysregulated amino acid transport and activation of the integrated stress response in the DTG-treated organoids, and functionally, a small molecule integrated stress response inhibitor (ISRIB) could partially rescue increased expression of proteins related to cell cycle regulation.…”

Image 2_An experimental chimeric hepatitis E virus vaccine elicits both local and systemic immune responses.tif by Melisa Florencia Müller (20471819)

“…Most groups produced significantly higher IgA levels in intestinal fluid, especially in those that received the oral scheme. …”

Table 3_Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic n... by Junming Huang (478336)

“…Finally, functional studies were conducted using Small interfering RNA (siRNA)-mediated gene knockdown to predict the biological roles of selected targets.…”

Table 2_Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic n... by Junming Huang (478336)

“…Finally, functional studies were conducted using Small interfering RNA (siRNA)-mediated gene knockdown to predict the biological roles of selected targets.…”

Image 4_Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic n... by Junming Huang (478336)

“…Finally, functional studies were conducted using Small interfering RNA (siRNA)-mediated gene knockdown to predict the biological roles of selected targets.…”

Image 3_Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic n... by Junming Huang (478336)

“…Finally, functional studies were conducted using Small interfering RNA (siRNA)-mediated gene knockdown to predict the biological roles of selected targets.…”

Data Sheet 1_Safety of unconventional antibody-drug conjugate L-DOS47 in a phase I/II monotherapy study targeting advanced NSCLC.docx by Rodryg Ramlau (22028390)

“…Introduction<p>Tumor acidity is emerging as a hallmark of cancer and carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) expression is frequently increased in acidic tumors. L-DOS47, a novel antibody-drug conjugate (ADC), consists of jack bean urease cross-linked to anti-CEACAM6 nanobodies. …”

Table 4_Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic n... by Junming Huang (478336)

“…Finally, functional studies were conducted using Small interfering RNA (siRNA)-mediated gene knockdown to predict the biological roles of selected targets.…”

Table 1_Incidence, risk factors and evolving treatment of severe retinopathy of prematurity in China: a retrospective multicenter cohort study in 70 neonatal intensive care units.d... by Xuting Chen (18993950)

“…Extremely preterm birth (7.61, 95% CI: 6.12–9.46), small for gestational age (SGA; 2.31, 95% CI: 1.71–3.12), outborn status (1.43, 95% CI: 1.22–1.67), 1-min Apgar score < 7 (1.30, 95% CI: 1.11–1.51), >40 days on oxygen (1.70, 95% CI: 1.37–2.10), >28 days on parenteral nutrition (PN; 1.17, 95% CI: 1–1.35), and any inotropes use (2.12, 95% CI: 1.82–2.46) were associated with increased odds of severe ROP. …”

Image 1_An experimental chimeric hepatitis E virus vaccine elicits both local and systemic immune responses.tif by Melisa Florencia Müller (20471819)

“…Most groups produced significantly higher IgA levels in intestinal fluid, especially in those that received the oral scheme. …”

Data Sheet 2_Effects of Tanreqing injection against ventilator-associated pneumonia: a meta-analysis and systematic review of clinical studies.docx by Pochen Li (17906738)

“…However, some of the included clinical studies had limitations such as small sample sizes, lack of sample size calculations. …”

The Key to Spinal Cord Recovery: Harnessing p21 Inhibition to Boost Neural Stem/Progenitor Cell Proliferation by Tiandi Xiong (11875031)

“…^<i>P21</i><i>siRNA</i>@LP significantly increased the primary NSPC proliferation rate (145.4% on day 1 and 144.7% on day 3, respectively) while maintaining differentiation capacity <i>in vitro</i>. …”

Table 1_Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical development.xlsx by Emma LaNoce (20129628)

“…Mechanistically, RNA-sequencing and immunohistological analysis suggests dysregulated amino acid transport and activation of the integrated stress response in the DTG-treated organoids, and functionally, a small molecule integrated stress response inhibitor (ISRIB) could partially rescue increased expression of proteins related to cell cycle regulation.…”

The Key to Spinal Cord Recovery: Harnessing p21 Inhibition to Boost Neural Stem/Progenitor Cell Proliferation by Tiandi Xiong (11875031)

“…^<i>P21</i><i>siRNA</i>@LP significantly increased the primary NSPC proliferation rate (145.4% on day 1 and 144.7% on day 3, respectively) while maintaining differentiation capacity <i>in vitro</i>. …”