Data Sheet 12_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Data Sheet 10_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Data Sheet 3_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Data Sheet 1_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Data Sheet 6_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Data Sheet 7_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Table_1_Exploring the potential role of microbiota and metabolites in acute exacerbation of chronic obstructive pulmonary disease.pdf حسب Yanmin Shi (16516917)

"…However, the relative abundance of Haemophilus_D, Veillonella_A and Pseudomonas_E, in AECOPD patients was significantly higher than that of COPD patients, and the ability of respiratory microbiota in AECOPD patients to participate in alanine metabolism was significantly lower than that of COPD patients. …"

Table_3_Exploring the potential role of microbiota and metabolites in acute exacerbation of chronic obstructive pulmonary disease.pdf حسب Yanmin Shi (16516917)

"…However, the relative abundance of Haemophilus_D, Veillonella_A and Pseudomonas_E, in AECOPD patients was significantly higher than that of COPD patients, and the ability of respiratory microbiota in AECOPD patients to participate in alanine metabolism was significantly lower than that of COPD patients. …"

Table_2_Exploring the potential role of microbiota and metabolites in acute exacerbation of chronic obstructive pulmonary disease.pdf حسب Yanmin Shi (16516917)

"…However, the relative abundance of Haemophilus_D, Veillonella_A and Pseudomonas_E, in AECOPD patients was significantly higher than that of COPD patients, and the ability of respiratory microbiota in AECOPD patients to participate in alanine metabolism was significantly lower than that of COPD patients. …"

Data Sheet 1_Impact of drought stress on biochemical and molecular responses in lavender (Lavandula angustifolia Mill.): effects on essential oil composition and antibacterial acti... حسب Ramin Hosseini (21023861)

"…As water availability decreased, we observed a reduction in total protein and chlorophyll content, while the highest levels of flavonoids, phenolics, and antioxidant activity were recorded in control plants at 80% FC. …"

Atorvastatin neuronal morphology data_CP.xlsxData set: neuronal morphology حسب Carolyn Pytte (20641508)

"…Our findings indicate that atorvastatin may affect neural cytoarchitecture in both newly formed and mature neurons, perhaps as a consequence of decreased cholesterol availability in the brain.…"

The effect of IFN-β and Vit D on the IL-1β and IL-10 protein production. حسب Farzad Nasri (8941850)

"…IFN-β and Vit D alone or together decreased IL-1β and IL-10 protein level, significantly in comparison with the control <b>(A, B)</b>. …"

High-throughput single-cell analysis reveals Omp38-specific monoclonal antibodies that protect against <i>Acinetobacter baumannii</i> infection حسب Yiwei Zhang (1448599)

"…Intravenous administration of the Omp38-specific mAbs significantly improved the survival rate and reduced the bacterial load in a mouse model of lethal <i>A. baumannii</i> infection. …"

Data Sheet 1_NLRP3 regulates epithelial barrier integrity and protects from airway hyperresponsiveness in experimental allergic asthma.pdf حسب Stephanie DeStefano (15457187)

"…Analysis of epithelial cell markers revealed decreased gene expression of the tight junction proteins Cld-18 and Tjp-1, and decreased expression of the epithelial transmembrane protein E-cadherin in the lungs of naïve NLRP3^-/- mice compared to WT mice. …"

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function حسب Gwenaëlle Jézéquel (4488268)

"…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …"

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function حسب Gwenaëlle Jézéquel (4488268)

"…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …"

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function حسب Gwenaëlle Jézéquel (4488268)

"…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …"

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function حسب Gwenaëlle Jézéquel (4488268)

"…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …"

Supplementary file 1_Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.doc حسب Zhenghao Wu (9732511)

"…For in vitro experiments, hepatic stellate cells, macrophages and lymphatic endothelial cells were used to observe the multiple effects of FN.</p>Results<p>FN significantly ameliorated portal pressure in cirrhosis-induced PHT, improved liver function, and reduced liver fibrosis and hepatic stellate cell activation with decreased SMAD3 protein expression. …"

Data Sheet 1_Serum metabolomics reveal the mechanisms by which fermented brewer’s spent grains promote intestinal development in white-feathered broilers.zip حسب Yuanfeng Li (217864)

"…Specifically, key DEMs involved in amino acid metabolism included significantly increased phenylalanine levels and decreased 4-HPA and 3-HPA levels (p < 0.05). …"