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20701
Data Sheet 1_In silico molecular studies of Phosphinogold(I) thiocarbohydrate complexes: insights into multi-target anticancer mechanisms.docx
Published 2025“…Complex 13 demonstrated high in vitro activity against prostate, colon, and breast cancer cell lines (IC50 = 0.03, 0.25, and 0.07 μM respectively), collaborating with a significant interaction with Human Epidermal Growth Factor Receptor 2 (HER2) (–71.15 kcal/mol binding affinity) in silico. …”
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20702
Table_1_Oxidative stress and inflammation mediate the association between elevated oxidative balance scores and improved sleep quality: evidence from NHANES.docx
Published 2024“…Sensitivity analyses revealed a significant association between OBS and sleep disorder (p < 0.001).…”
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20703
Table 1_Probabilistic human health risk assessment of commercially supplied jar water in Gopalganj municipal area, Bangladesh.docx
Published 2024“…<p>Every day, the amount of quality fresh water decreases notably due to contamination of drinking water. …”
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20704
DataSheet1_Shenshuaikang enema restores the intestinal barrier and microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-κB pathway.docx
Published 2025“…It has become a significant public health problem, posing a threat to human health worldwide. …”
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20705
Table 1_Burden of non-CO poisoning in 204 countries and territories, 1990–2021: results from the global burden of disease study 2021.docx
Published 2025“…Background<p>Non-carbon monoxide (non-CO) poisoning remains a significant global public health issue, contributing to considerable morbidity and mortality. …”
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20706
Data Sheet 1_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.xlsx
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. …”
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20707
Image 2_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff
Published 2025“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”
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20708
Data Sheet 2_Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.docx
Published 2025“…Subsequent in vitro experiments demonstrated that silencing APOC1 reduced the generation of tumor-associated macrophages (TAMs) with an M2 phenotype while significantly decreasing the proliferation, invasion, and migration of MDA-MB-231 and MDA-MB-468 breast cancer cell lines.…”
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20709
Data Sheet 1_Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.csv
Published 2025“…Subsequent in vitro experiments demonstrated that silencing APOC1 reduced the generation of tumor-associated macrophages (TAMs) with an M2 phenotype while significantly decreasing the proliferation, invasion, and migration of MDA-MB-231 and MDA-MB-468 breast cancer cell lines.…”
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20710
CLAD_sequence_files
Published 2025“…</b>BALF metabolomes varied by underlying disease state, with AATD LT recipients being particularly distinctive (PERMANOVA, <i>p</i>= 0.001, F= 3.91). We also found a significant association with the final CLAD severity score (RF variance explained = 11.08%, PERMANOVA, <i>p</i>=0.001), especially those with underlying CF. …”
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20711
Supplementary file 1_Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis.docx
Published 2025“…Background<p>Traumatic brain injury (TBI) represents a major global health challenge. Several clinical studies have suggested that Xuebijing (XBJ)—a patented Chinese botanical drug preparation may confer neuroprotective and anti-inflammatory benefits in TBI. …”
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20712
3D Nanoscale Structures of Hydrated Polyamide Desalination Membranes Revealed by Cryogenic Transmission Electron Microscopy Tomography
Published 2025“…Additionally, while the surface area decreases upon hydration for both SW and BW membranes, indicating a smoothing of surface nodules and cavities, surface roughness remains unchanged, suggesting that current roughness measurement methods such as atomic force microscopy do not capture intrinsic morphological features. …”
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20713
Baseline characteristics of the study population.
Published 2025“…<div><p>Background</p><p>Intravenous immunoglobulin is a replacement therapy for patients living with primary immunodeficiencies. …”
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20714
Table 1_Global, regional, and national anemia burden among women of reproductive age (15–49 years) from 1990 to 2021: an analysis of the Global Burden of Disease Study 2021.docx
Published 2025“…Background<p>Anemia remains a significant global health challenge, disproportionately affecting women of reproductive age (WRA, 15 to 49 years) due to physiological and socioeconomic factors. …”
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20715
Table 1_Effect of high-intensity intermittent rehabilitation training on physical function, gut microbiome and metabolite after percutaneous coronary intervention in patients with...
Published 2024“…In addition, we identified 29 gut microbial species and 30 plasma metabolites that were differentially enriched between the two groups, with some showing a significant impact on 6MWT performance.</p>Conclusions<p>High-intensity interval training significantly improves 6MWT performance and exercise tolerance in cardiac rehabilitation patients, particularly enhancing VO2 peak in those with a history of MI. …”
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20716
Data Sheet 2_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. …”
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20717
Image 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff
Published 2025“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”
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20718
Data Sheet 6_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. …”
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20719
Patient disposition.
Published 2025“…<div><p>Background</p><p>Intravenous immunoglobulin is a replacement therapy for patients living with primary immunodeficiencies. …”
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20720
Supplementary file 1_Integrating Drosophila and Vibrio fischeri models for toxicity evaluation: uncovering detoxification trends in psoralea Fructus-TCM formulations.docx
Published 2025“…Enzyme assays indicated a decreasing toxicity trend for ESP and SSP compared to PF, with significant changes observed in female flies. …”