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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), mean decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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5501
Data Sheet 1_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.pdf
Published 2025“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”
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5502
Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx
Published 2025“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”
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5503
SEAwise synthetic summary report of the findings of WP4 on changes to the ecosystem impacts of fishing in response to spatial management for online tool
Published 2025“…Almost all management strategies except current management led to overall decreases in effort and as a result, the general ecosystem impact to a level where GES was attained (habitats and foodwebs) or the impact was decreased by at least 20% (bycatch). …”
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5504
Fertilization and herbivore exclusion promote more deterministic processes in plant community assembly on the Qinghai–Tibet Plateau
Published 2025“…However, the extent to which these factors influence the relative contributions of deterministic and stochastic processes in community assembly remains poorly understood. In this study, we conducted a five-year field experiment that manipulated nutrient availability and herbivore exclusion in an alpine grassland on the eastern Qinghai–Tibet Plateau. …”
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5505
Table 1_Predicting psychiatric risk: IgG N-glycosylation traits as biomarkers for mental health.xls
Published 2024“…High levels of IGP21 were associated with an increased risk of post-traumatic stress disorder (PTSD), while elevated levels of IGP22 exhibited a causal association with a decreased risk of attention-deficit/hyperactivity disorder (ADHD). …”
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5506
Wheat germ agglutinin-nanoparticles encapsulating itacitinib target and suppress pro-inflammatory slan+ monocytes
Published 2025“…<p>6-sulfoLacNAc (slan)+ monocytes, a non-classical monocyte subset, play a pro-inflammatory role in autoimmune diseases like systemic lupus erythematosus (SLE). …”
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5507
Data Sheet 1_Lysate of Parabacteroides distasonis prevents severe forms of experimental autoimmune encephalomyelitis by modulating the priming of T cell response.docx
Published 2024“…Pd lysate could thus be a future modulator of neuroinflammation that increases the resistance to multiple sclerosis.…”
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5508
Supplementary Material for: High expression of tetraspanin CD63 predicts poor prognosis in esophageal squamous cell carcinoma
Published 2025“…Herein, we report the significance of CD63 expression by analyzing ESCC patient samples and ESCC cell lines. …”
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5509
Data Sheet 1_Investigating the underlying mechanisms of the ethanol extract of saussureae involucratae herba in anti-rheumatoid arthritis effect based on sphingolipidomics.pdf
Published 2025“…In cell assays, SIE significantly decreased the protein levels of TNF-α and IL-6 (both P < 0.01) in LPS-stimulated RAW 264.7 cells. …”
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5510
All data.
Published 2025“…Metabolomics analysis revealed that inulin treatment significantly modulated the levels of 8 stage-specific metabolites; notably, it increased anti-inflammatory, anti-diabetic and neuroprotective metabolites taurine and dodecanoic acid in prediabetic mice, while decreasing pro-inflammatory mediators including oleamide and adrenic acid. …”
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5511
Supplementary Material for: Splice variant of retinal G-protein-coupled receptor deletion (RGR-d)-mediated dysregulation of autophagy increases the susceptibility to age-related ma...
Published 2024“…Beclin-1 and LC3II/I expression levels were significantly decreased and that of P62 was elevated in RGR-d cells after PA stimulation. …”
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5512
Table 1_Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease.doc
Published 2025“…</p>Methods<p>In this study, we investigated the efficacy and underlying mechanisms of Nar in a mouse model of high-fat diet (HFD)-induced MASLD using integrated analyses of network pharmacology, molecular docking, hepatic lipidomics, and gut microbiota.…”
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5513
The inhibitory and anti-inflammatory effects of TMP269 on peste des petits ruminants virus replication
Published 2025“…The replication of many viruses is closely related to the regulation of histone deacetylases (HDACs). TMP269, a selective class IIa HDAC inhibitor, plays an important role in cancer therapy and also modulates viral replication. …”
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5514
Data_Sheet_1_Optimisation of Lactobacillus fermentation conditions and its application in the fermentation of salt-free sauerkraut.PDF
Published 2024“…<p>To identify what are the dominant lactic acid bacteria (LAB) involved in the fermentation of salt-free sauerkraut, and optimize its industrial culture conditions, we isolated and identified a strain of LAB, which is referred to as Lactobacillus sp. …”
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5515
Data Sheet 1_Membrane filtration reduces nutrient availability and invasion potential in drinking water systems, without affecting mature biofilms.docx
Published 2025“…In this study, we evaluated the efficacy of ultrafiltration (UF) and nanofiltration (NF) in reducing total organic carbon (TOC) and their impact on the microbiology in a pilot-scale drinking water distribution system over 7 weeks. …”
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5516
Data Sheet 1_MDSC depletion during immunization with heat-killed Mycobacterium tuberculosis increases protection against BCG infection.pdf
Published 2025“…Thus, we hypothesized that the defense against a subsequent BCG infection would be compromised in Mtb-immunized mice. …”
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5517
Data Sheet 1_Dual upregulation of miRNA-143 and miRNA-506 in non-small cell lung cancer inhibits proliferation, motility, migration, and tumor growth.pdf
Published 2025“…Following stable transductions using lentiviruses in A549 and H1975 cells, we evaluated cell cycle distribution, proliferation, migration, and in vivo tumor growth. …”
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5518
Does policy integration in renewable energy deployment enhance environmental sustainability in Africa?
Published 2024“…<p>In recent years, the world has observed a steady rise in protective measures toward environmental sustainability, especially in developing countries like Africa, which is seen as a lower contributor to global pollution but is not exempted from the consequences of ozone layer depletion leading to global warming. …”
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5519
Data Sheet 1_Effect of high intakes of protein-only and carbohydrate-only on plasma metabolites and hormones, in addition to nitrogen excretion.xlsx
Published 2025“…The aims of this study were to compare the metabolic and hormonal responses to isocaloric intakes of whey protein alone versus carbohydrate alone. Additionally, we measured urinary nitrogen excretion as a marker of protein degradation.…”
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5520
Data_Sheet_1_Guanxin Danshen Formulation Protects against Myocardial Ischemia Reperfusion Injury-Induced Left Ventricular Remodeling by Upregulating Estrogen Receptor β.DOC
Published 2024“…Target validation was conducted by using western blots and immunofluorescent double staining assays.</p><p>Results: We found that +dp/dt and LVSP were significantly elevated in the GXDSF-treated groups compared with the MIRI-LVR model group. …”