Liver ferroptosis caused by <i>C. sinensis</i> infection in mice by Haoyang Zhang (1706815)

Development of a User-Friendly Dynamic Culture System for Decellularized Scaffold-Based Tissue Engineering by Shujuan Fan (8380047)

“…Compared to static controls, constructs cultured in our platform exhibited a > 5-fold increase in proliferating (Ki67+) cells and a 32-fold decrease in apoptotic (TUNEL+) cells. Hepatic functions were also significantly enhanced, with increased urea production and markedly higher expression of albumin (∼1.5-fold) and the key metabolic enzymes UGT1 (∼1.4-fold) and CYP2D6 (∼2.7-fold). …”

Frequency distribution of depths of coverage (DP) and allele balances (AB). by Eileen Marie Hanna (9693992)

Data Sheet 2_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.pdf by Juan Zhang (48597)

“…In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”

Data Sheet 1_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.docx by Juan Zhang (48597)

“…In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”

Image 1_Global burden trends and future predictions of ischemic heart disease attributable to air pollution in people aged 60 years and older, 1990–2021.jpeg by Yuanqin Zhao (4435384)

“…</p>Results<p>Between 1990 and 2021, global IHD burden attributable to AP in individuals aged 60 and above rose in terms of deaths, DALYs, YLDs and YLL, while there was a decline in ASRs. Overall, the disease burden in the older adult population remains high, with older age groups experiencing the greatest burden and the most significant decrease in ASRs. …”

Table 1_Neural correlates of subjective cognitive decline in Alzheimer’s disease: a systematic review of structural and functional brain changes for early diagnosis and interventio... by Giulia Marafioti (21163931)

“…Dynamic functional connectivity studies report reduced brain activity efficiency, while graph theory analyses show decreased network integration. Advanced neuroimaging techniques and machine learning (ML) approaches demonstrate significant promise in detecting subtle neural changes in SCD, with applications for early diagnosis and monitoring disease progression.…”

Data Sheet 1_Global, regional, and national burden of sudden infant death syndrome, 1990–2021: a comprehensive analysis of GBD 2021 data with insights into the impact during the CO... by Yuhan Sun (299077)

“…Mortality and DALYs rates decreased by 59% from 1990 to 2021, with marked regional differences. …”

Table 2_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.csv by Siying Wei (5990276)

“…</p>Conclusion<p>This study highlights marked disparities in the disease burden among age groups across diverse SDI regions. …”

Table 1_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.csv by Siying Wei (5990276)

“…</p>Conclusion<p>This study highlights marked disparities in the disease burden among age groups across diverse SDI regions. …”

Image 1_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.tiff by Siying Wei (5990276)

“…</p>Conclusion<p>This study highlights marked disparities in the disease burden among age groups across diverse SDI regions. …”

Table 3_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.csv by Siying Wei (5990276)

“…</p>Conclusion<p>This study highlights marked disparities in the disease burden among age groups across diverse SDI regions. …”

Table 4_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.xlsx by Siying Wei (5990276)

“…</p>Conclusion<p>This study highlights marked disparities in the disease burden among age groups across diverse SDI regions. …”

Restriction of mitochondrial oxidation of glutamine or fatty acids enhances intracellular growth of <i>Mycobacterium abscessus</i> in macrophages by Ho Won Kim (18237328)

“…R-type Mab infections exhibited a marked decrease in glutamine reliance but enhanced metabolic flexibility and capacity. …”

Study group background characteristics. by Zicheng Hu (3825313)

“…This relationship changed markedly with the development of <b><i>HAD</i></b> and the underlying direct neuropathic parenchymal CNS infection, i.e., <b><i>HIVE</i></b>, in which the CSF HIV-1 RNA concentrations reached high levels, and the differences between it and the blood viral load decreased. …”

Neuroprotective effects of Cannabidiol in 5XFAD Mice: Reducing amyloid and tau burden in the dorsal subiculum by Muhammad Kamal Hossain (19814445)

“…Interpretation:</b> Our results showed that CBD treatment led to a significant reduction in Aβ accumulation and a marked decrease in hyperphosphorylated tau in treated mice compared to controls. …”

Table 1_Proton therapy achieves high-dose tumor control with organ preservation in complex metastatic adenoid cystic carcinoma: a case report of a refractory patient with 16 pulmon... by Zejun Lu (2279458)

“…Therapeutic options for locally advanced or metastatic ACC are limited, and conventional radiotherapy is often constrained by dose limitations for multifocal disease, leading to inadequate treatment. …”

Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf by Ying Xiao (6517)

“…</p>Results<p>Globally, the incidence of pediatric IE declined by 27.6% (95% UI, −30.9% to −24.9%) and mortality by 21.4% (95% UI, −35.2% to −0.8%) between 1990 and 2021, with an estimated annual percentage change (EAPC) of −1.37% (95% CI, −1.49% to −1.24%) and −0.64% (95% CI, −0.75% to −0.54%), respectively. DALYs decreased by 19.2% (95% UI, −33.2% to 1.9%). Marked disparities persisted, with high-SDI regions, notably China, achieving the greatest reductions in burden, while sub-Saharan Africa and Eastern Europe exhibited stagnant or increasing rates. …”

Table 1_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf by Ying Xiao (6517)

“…</p>Results<p>Globally, the incidence of pediatric IE declined by 27.6% (95% UI, −30.9% to −24.9%) and mortality by 21.4% (95% UI, −35.2% to −0.8%) between 1990 and 2021, with an estimated annual percentage change (EAPC) of −1.37% (95% CI, −1.49% to −1.24%) and −0.64% (95% CI, −0.75% to −0.54%), respectively. DALYs decreased by 19.2% (95% UI, −33.2% to 1.9%). Marked disparities persisted, with high-SDI regions, notably China, achieving the greatest reductions in burden, while sub-Saharan Africa and Eastern Europe exhibited stagnant or increasing rates. …”

Table 3_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf by Ying Xiao (6517)

“…</p>Results<p>Globally, the incidence of pediatric IE declined by 27.6% (95% UI, −30.9% to −24.9%) and mortality by 21.4% (95% UI, −35.2% to −0.8%) between 1990 and 2021, with an estimated annual percentage change (EAPC) of −1.37% (95% CI, −1.49% to −1.24%) and −0.64% (95% CI, −0.75% to −0.54%), respectively. DALYs decreased by 19.2% (95% UI, −33.2% to 1.9%). Marked disparities persisted, with high-SDI regions, notably China, achieving the greatest reductions in burden, while sub-Saharan Africa and Eastern Europe exhibited stagnant or increasing rates. …”