Table 1_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”

Table 3_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx by Wang Yu (8537490)

“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”

Table 3_Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.docx by Ling Zhou (51948)

“…Similarly, rheumatoid factor (RF) levels significantly decreased after treatment (MD = −318.20,95%CI:−364.66,−271.73) and remained low at the 6-month follow-up (MD = −287.78, 95%CI:−511.58,−63.97).…”

Data Sheet 2_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf by Ying Liu (18461)

“…Background<p>Esophageal cancer remains one of the deadliest cancers globally, highlighting significant health challenges and socioeconomic disparities. …”

Table 1_Socio-hydrology and sustainable tank management: empirical case from a Mailam tank cascade, Tamil Nadu, India.xlsx by Raj Rengalakshmi (12058247)

“…The dependence on tanks for irrigation by farmers in the study area has decreased, ranging from 9 to 54%. There has been a significant change in land use; a 44% reduction in the area under cropping (1,707 ha to 954 ha), with a 13% increase in fallow land (1,607 ha to 1,822 ha) and a 43% increase in other vegetation and built-up area from 5 ha to 60 ha. …”

Image1_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg by Saeko Yamada (11899439)

“…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…”

Heterotrophic cell growth and dry cell yield of <i>Rhodovulum sulfidophilum</i> in artificial seawater (ASW) based growth medium of different salinities, wherein 100% corresponds t... by Shamitha Rao Morey-Yagi (19779981)

“…Asterisks indicate significant differences between 100% and decreasing concentrations of ASW tested using one-way ANOVA (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0321821#pone.0321821.g001" target="_blank">Figs 1b</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0321821#pone.0321821.g001" target="_blank">1c</a>) or two-way ANOVA (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0321821#pone.0321821.g001" target="_blank">Fig 1a</a>), and the Dunnett’s multiple comparison test (GraphPad Prism 9); * p < 0.05, ** p < 0.01, and *** p < 0.001.…”

Data Sheet 1_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf by Ying Liu (18461)

“…Background<p>Esophageal cancer remains one of the deadliest cancers globally, highlighting significant health challenges and socioeconomic disparities. …”

Table 6_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.docx by Ying Liu (18461)

“…Background<p>Esophageal cancer remains one of the deadliest cancers globally, highlighting significant health challenges and socioeconomic disparities. …”

Image2_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg by Saeko Yamada (11899439)

“…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…”

SEAwise synthesis of predicted impacts of changes in habitat and spatial management measures suggested in SEAwise for online tool by Dimitris Damalas (15976639)

“…This SEAwise report synthesizes all spatial aspects of stocks and fisheries spanning from environmental drivers to habitat change and management options.…”

Table 6_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx by Nirmal Parajuli (751983)

“…Our recent study found that the loss of miRNAs in embryonic progenitors significantly decreased the number of TR-AMs in late-stage embryos, indicating that miRNAs are necessary for TR-AM development. …”

Classification of land use index. by Hui Li (32376)

“…Our results indicate significant changes in land types within the TGRR from 1986 to 2020, with decreases in arable land, forest land, and grassland, while water bodies, building land, and unused land increased. …”

Data Sheet 1_Association of body roundness index with cardiovascular disease in patients with cardiometabolic syndrome: a cross-sectional study based on NHANES 2009-2018.pdf by Xiaohua He (361530)

“…For CVD, stratified analyses did not show significant difference between strata. For CHF, BMI interacted with the association, with BRI being associated with decreased risk of CHF in a subgroup of normal weight subjects and increased risk of CHF in a subgroup of obese subjects. …”

Image3_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4⁺ and CD8⁺ T cells in implanted limb muscles of mouse models. …”

Image4_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Table 4_Association between cardiovascular health and markers of liver function: a cross-sectional study from NHANES 2005–2018.docx by Huang Yu (5882174)

“…</p>Results<p>Linear regression analysis showed that each 1-point increase in CVH score was significantly associated with decreased levels of liver enzymes [ALT: −0.200 U/L (95% CI: −0.223, −0.176), AST: −0.043 U/L (−0.062, −0.024), GGT: −0.453 U/L (−0.509, −0.397), ALP: −0.310 U/L (−0.340, −0.281)] and increased levels of albumin [0.040 g/dL (0.036, 0.045)] and AST/ALT ratio [0.0056 (0.0051, 0.0061)]. …”

Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf by Junjie Jiang (7255706)

“…</p>Results<p>Analysis of data from the 2011–2018 NHANES survey revealed a significant negative association between CDAI and sleep disorders (OR = 0.854, 95% CI 0.821–0.888, P < 0.001). …”

Data Sheet 1_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”

Supplementary Material for: Exosomal TIMP4 from myocardial cell relieves heart failure by influencing Th17/Treg Balance by figshare admin karger (2628495)

“…Results: Analysis of the GSE196656 dataset revealed significant upregulation of TIMP4 in heart failure. …”