Data Sheet 2_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.docx by Quan Lin (5958)

“…SQOR knockdown resulted in decreased cell viability, decreased migration ability and increased MDA level under hypoxic Ersatin induced conditions. …”

Data Sheet 1_Menthone lowers H3K27ac levels to inhibit Fusarium proliferatum growth.docx by Li-Yan Zhang (5091608)

“…</p>Results<p>This study demonstrated that menthone, the primary component of Mentha haplocalyx EO, exhibited notable antifungal activity against Fusarium proliferatum (EC50 = 6.099 mmol/L). The treatment significantly inhibited hyphal growth, reduced spore germination rates from 31.49 to 4.95%, decreased spore viability from 46.88 to 20.91%, and reduced spore production by a factor of 17.92 compared with the control group while simultaneously enhancing cell membrane permeability. …”

Table 4_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”

Supplementary Material for: Efficacy of Spray Cryotherapy on Airway Secretions in Canine Models of Chronic Bronchitis and Mechanism Insights by Wang B. (4026758)

“…SCT treatment reduced mucus and pulmonary resistance, improved bronchial structure, and decreased goblet cells. SCT significantly reduced BALF mucin, MUC5AC, MUC5B, acetylcholine, IL-6, INF-γ, TNF-α, and IL-10, and bronchial MUC5AC and CHRM3. …”

Changes to the host transcriptome during infection. by Stefan Bresson (20623940)

“…The heatmap shows the most significantly decreased transcripts (by <i>p</i>-value). …”

Data Sheet 1_Brackish water irrigation boosts honeysuckle (Lonicera japonica Thunb.)-salt tolerance by regulating sodium partitioning and potassium homeostasis: implications for co... by Yu Shi (117923)

“…</p>Results<p>With increasing brackish water irrigation, (1) significantly reduced cation accumulation in the topsoil. …”

N6-methyladenosine modification of THBS1 induced by affluent WTAP promotes Graves’ ophthalmopathy progression through glycolysis to affect Th17/Treg balance by Lin-na Li (20442989)

“…WTAP was significantly upregulated in CD4⁺ T cells of GO, and WTAP silencing significantly reduced m6A abundance and expression of THBS1. …”

Trimester-specific thyroid function markers and gestational diabetes risk: evidence from a tertile-based cohort of euthyroid pregnancies by Erkan Sağlam (21764816)

“…TSH levels increased, while fT3 and fT4 levels decreased significantly across trimesters (<i>p</i> < 0.001). …”

Data Sheet 1_The CENPN/STAT3/USP37 signaling axis promotes invasion, migration and metastasis in nasopharyngeal carcinoma.docx by Yu-Fei Wang (322119)

“…</p>Results<p>The invasion and migration capacities of nasopharyngeal carcinoma cells decreased significantly after CENPN knockdown, whereas the overexpression of CENPN significantly promoted the invasion and metastasis abilities of nasopharyngeal carcinoma cells. …”

Raw data DOI 10.3389fphar.2024.1483686.zip by Changlin Wang (19822068)

“…In terms of mechanism, JJJG significantly increased the levels of FT3 and FT4 and decreased TSH level in serum (P<0.05). …”

Image 1_Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness.tif by Caiyi Xu (21535451)

“…Bubble-induced injury significantly decreased the viability of PMVECs and increased the levels of endothelial microparticles, inflammatory cytokines, and endothelial injury markers in culture media. …”

<i>Hif-1α</i> ablation reduces the efficiency of NeuroD1 gene-based therapy and aggravates the brain damage following ischemic stroke by Nashwa Amin (11242159)

“…Meanwhile, <i>Hif-1α</i> ablation significantly decreased the efficiency of NeuroD1 gene-based therapy.…”

Impact of acute binge-like ethanol exposure during the third-trimester equivalent on subicular interneurons in mice by Katalina M. Lopez (21821714)

“…Adolescent neuronal density was significantly decreased in exposed males’ distal dorsal subiculum (<i>p</i> < .0001, g = −0.8). …”

Image 1_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.tif by Na Chen (153323)

“…Our previous study showed that R. solanacearum significantly upregulates SlWRKY75 expression in tomato. …”

Data Sheet 1_Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway.pdf by Zulipikaer Wusiman (20852138)

“…GA has a strong binding affinity for important targets.GA significantly increased the expression of genes such as mapk8b, mapk14a, mapk3, mitf, tyr, tyrp1b, tyrp1a, dct, and oca2, and decreased the expression of genes such as expression of genes such as raf1 and egfr. …”

Image 2_Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness.tif by Caiyi Xu (21535451)

“…Bubble-induced injury significantly decreased the viability of PMVECs and increased the levels of endothelial microparticles, inflammatory cytokines, and endothelial injury markers in culture media. …”

Table1_The interaction between selenium and other elements in soil and rice roots shaped by straw and straw biochar regulated the enrichment of selenium in rice grain.docx by Qinlei Rong (3815335)

“…The results showed that the incorporation of straw and straw biochar into the fields increased the content of soil-soluble Se (SOL-Se) but significantly decreased the content of iron-manganese oxide-bound Se (FMO-Se) and organic matter-bound Se (OM-Se). …”

Data Sheet 1_Real-world analysis of leuprorelin acetate microspheres-based neoadjuvant therapy for patients with high-risk prostate cancer.docx by Changde Fu (20899748)

“…Testosterone showed a decreased tendency after neoadjuvant therapy, but without statistical significance (P=0.185). …”

Table 2_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.doc by Na Chen (153323)

“…Our previous study showed that R. solanacearum significantly upregulates SlWRKY75 expression in tomato. …”

Supplementary Material for: Identifying novel inflammatory protein biomarkers and drug targets of inflammatory bowel disease by integrating Mendelian randomization, bioinformatics,... by Wang F. (3215361)

“…Additionally, CD was significantly associated with elevated levels of three circulating inflammatory proteins, which are suggested to be the consequences of CD. …”