Data Sheet 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.xlsx by Xiong-Gang Yang (22645370)

“…Polynomial analyses revealed optimal stress reductions within specific elastic modulus ranges (400, 800, and 1,000 kPa in compressive, AP-shear, and ML-shear dimensions, respectively), indicating diminishing benefits beyond these points.</p>Conclusion<p>FEA revealed that heel cushioning pads with tailored elastic moduli can significantly reduce peak stresses, with diminishing benefits observed beyond certain thresholds. …”

Image 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.jpeg by Xiong-Gang Yang (22645370)

“…Polynomial analyses revealed optimal stress reductions within specific elastic modulus ranges (400, 800, and 1,000 kPa in compressive, AP-shear, and ML-shear dimensions, respectively), indicating diminishing benefits beyond these points.</p>Conclusion<p>FEA revealed that heel cushioning pads with tailored elastic moduli can significantly reduce peak stresses, with diminishing benefits observed beyond certain thresholds. …”

Table 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.docx by Xiong-Gang Yang (22645370)

“…Polynomial analyses revealed optimal stress reductions within specific elastic modulus ranges (400, 800, and 1,000 kPa in compressive, AP-shear, and ML-shear dimensions, respectively), indicating diminishing benefits beyond these points.</p>Conclusion<p>FEA revealed that heel cushioning pads with tailored elastic moduli can significantly reduce peak stresses, with diminishing benefits observed beyond certain thresholds. …”

Supplementary Material for: Minimal Change Disease and Focal Segmental Glomerulosclerosis are associated with good kidney prognosis and Thrombotic Microangiopathy with poor kidney... by Neves P.D.M.M. (20408168)

“…Moreover, the overall distribution of histological profiles showed significant particularities in the analyzed patient cohort, the most important being the higher frequency of TMA cases.…”

The effects of CHRM2 knockdown on osteogenic differentiation and cell proliferation. by Cheng Zhong (573294)

“…(B) The RT-qPCR results showed that the expression of CHRM2 in cells with Si-CHRM2 knockdown decreased significantly. (C) The cell proliferation were measured by OD value at 450 nm, and the observation time points were at 0, 24, 48, 72 and 96 hours. …”

Glucose and G-6-P levels modulate HK2-<i>SOX10</i> mRNA association and <i>SOX10</i> mRNA translation. by Ana Luisa Dian (22258504)

“…<p><b>(A)</b> Western blot analysis of HK2 and SOX10 protein level in A375 cells cultured for 24 h with decreasing concentrations of glucose or under glucose starvation, as indicated. …”

Impact of Gemin5 in protein synthesis: phosphoresidues of the dimerization domain regulate ribosome binding by Salvador Abellan (19499424)

“…Moreover, cap-dependent protein synthesis was significantly altered by the triple substitution STS/DDD, pointing towards a role of these residues in protein synthesis regulation.…”

Supplementary file 1_Comparative efficacy of femoral neck system vs. cannulated compression screws in young patients with femoral neck fractures: a systematic review and meta-analy... by Weishuai Zhang (22399933)

“…Meta-analysis revealed that, compared to CCS, FNS was associated with a significantly shorted fracture healing time (SMD = 16.30, 95% CI: 3.79–28.82, P < 0.001), decreased intraoperative fluoroscopy usage (WMD) = −8.14, 95% CI: −9.82 to −6.46, P < 0.001), and higher Harris hip scores at the final follow-up (WMD = −3.43, 95% CI: −4.08 to −2.77, P < 0.001). …”

Data_Sheet_1_Association of systemic immune-inflammation index with malnutrition among Chinese hospitalized patients: a nationwide, multicenter, cross-sectional study.docx by Mengyuan Chen (5633153)

“…Both lower and higher SII levels (either continuous or categorical variable) were significantly associated with an increased risk of malnutrition.…”

Supplementary file 3_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …”

Protein and gene expression levels of p62 and LC3B in miR-7974 mimic-transfected MCF-7 cells. by Stralina Eneh (21213312)

“…<b>(D)</b> The gene expression level of <i>LC3B</i> was decreased and <b>(E)</b> expression level of <i>p62</i> upregulated in miR-7974-treated MCF-7 cells. …”

Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf by Chun-Fei Wu (22315444)

“…Confocal microscopy demonstrated a significant increase in autophagic flux in Andro-treated SW1353 cells. …”

Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... by Wu Chen (569414)

“…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…”

Table 1_Effect of compound kushen injection on immune function in patients with colorectal cancer: a systematic review and meta-analysis.docx by Lixin Zhang (55947)

“…Chemotherapy and radiotherapy remain cornerstone treatments; however, they often lead to significant immune suppression and an increased risk of infection. …”

Supporting data for <b>Drivers, Composition and Potential for Innovative Vector Control Approaches in the mosquito</b> by Lucy Aliette Janet Mirabib Ame De Guilhem De Lataillade (11192853)

“…While most Bacteria and Viruses studied showed correlations with decreased immune gene expression, some, such as Doliuvirus or Siphonobacter, were associated with increased immune gene expression. …”

Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc... by Wenjing He (4278625)

“…MR analysis demonstrated a statistically significant causal association between TNF and CKD (OR = 1.02, <i>p</i> < 0.05), with positive trends for IL6 and CASP3. …”

Image 2_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg by Johnny Amer (495285)

“…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”

Repetitive stress modulates loudness perception. by Ghattas Bisharat (20706928)

“…Mice exhibited increased perceptual boundaries during repeated stress, indicating a decreased loudness perception (<i>t</i> test, <i>p</i> = 1.2 × 10⁻⁰⁵, mean ± SE). …”

Image 3_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg by Johnny Amer (495285)

“…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”

Table 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.docx by Johnny Amer (495285)

“…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”