Image 2_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.tif by Yuanbing Zhu (20538638)

Baseline clinical data. by Lu-Jin Cheng (21743350)

“…In vitro experiments showed that the addition of Gal-9 led to a significant increase in the proportion of TIM-3⁺M1 and TIM-3⁺M2 macrophages and a decrease in M1 cell proportions and M1/M2 ratio. …”

Data Sheet 1_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.pdf... by Yuanbing Zhu (20538638)

Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction by Zhihui Liu (95891)

“…Given that mitochondria are the primary source of reactive oxygen species (ROS), we assessed cellular ROS and mitochondrial superoxide levels by flow cytometry and found a significant increase. GOT1 knockdown increased the sensitivity of cells to cisplatin and decreased the volume of tumors in vivo. …”

This figure illustrates the impact of <i>Lactobacillus reuteri</i> supplementation on cytokine concentrations in a mouse model of colitis induced by dextran sulfate sodium (DSS). by Mohsen Nazari (6299819)

“…<p><b>(A)</b> Tumor necrosis factor-alpha (TNF-α): Pro-inflammatory cytokine levels were significantly elevated in the DSS group but were notably reduced in the group treated with <i>L. reuteri</i>. …”

DataSheet1_Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation.ZIP by Jing Lu (120666)

“…Yet little is known about apoA-I ’s role in peritoneal dialysis. In this study, by analyzing PD patients (n = 81), we found that decreased apoA/HDL-C ratio is significantly associated with rapid decline in peritoneal function. …”

5OMV Inhibits HMGB1-Induced Tube Formation in HUVECs. by Wenyue Hou (10203722)

“…Quantitative analysis <b>(F)</b> demonstrated a decrease in total tube numbers compared to HMGB1 stimulation alone, highlighting 5OMV’s potent anti-angiogenic activity (Vehicle control: 0.1% DMSO). …”

Data Sheet 1_Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.pdf by Nineth Rossi (22355524)

“…Introduction<p>Long COVID and post-COVID syndromes represent a significant global health crisis and a substantial societal challenge. …”

Table1_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... by Wenlei Wang (1514554)

“…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”

Table2_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... by Wenlei Wang (1514554)

“…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”

5OMV Inhibits HMGB1-Induced Microvascular Branch Formation in Rat Abdominal Aortic Rings. by Wenyue Hou (10203722)

Over expression of SOX6 attenuates apoptosis and DNA damage in AGS cells. by Yating Li (1819822)

PARP9 knockdown promotes apoptosis and DNA damage. by Yating Li (1819822)

“…(F) The anti-DNA damage capacity of GC cells decreased markedly following reduction of PARP9 expression. …”

Effects of intracisternal drug administration on the immunoreactivity of D2 receptor. by Hiroharu Maegawa (8087543)

“…N = 5 in each group. A significant decrease was found in the ION-CCI + CGRP Ab group as compared to the ION-CCI, ION-CCI + vehi, ION-CCI + CGRP, and ION-CCI + ctrl IgG groups. ** <i>p</i> < 0.01, * <i>p</i> < 0.05 compared to ION-CCI + CGRP Ab group. …”

Effects of administering drugs into the TG on the glial fibrillary acidic protein (GFAP)-IR cells. by Hiroharu Maegawa (8087543)

“…A significant decrease was found in the ION-CCI + CGRP Ab group as compared to the ION-CCI, ION-CCI + vehi, ION-CCI + CGRP, and ION-CCI + ctrl IgG groups. *** <i>p</i> < 0.001 as compared to the sham group. ## <i>p</i> < 0.01, # <i>p</i> < 0.05 as compared to the ION-CCI + CGRP Ab group. …”

Changes in cytokine production over the second week of culture. by Nils Ågren (21474419)

“…The decrease in IFN-γ production between days 9 and 14 was significant in all groups. …”

Average kidney and heart weight of rats. by Diana Bylan (20421873)

“…Dose-dependent experiments showed that COE (1 and 2μg/ml) induced a significant increase of phospho-(S473)-AKT along with a decrease in phospho (T180 + Y182) P38 levels.…”

PEDV and PDCoV infection impairs the cilium. by Tenghan Zhuang (22238809)

“…Notably, infection by either porcine epidemic diarrhea virus (PEDV) or porcine deltacoronavirus (PDCoV) resulted in a significant decrease in both the percentage of cells with cilium and the average ciliary length across all three porcine cell lines (<i>C-D, F-G, and I-J</i>). …”

Baseline analysis, nominal factors. by Hiroaki Yoshikawa (4615801)

“…</p><p>Results</p><p>Our analysis revealed a significantly older age of onset in the 2018 cohort compared to 2006. …”

Minimal dataset for the study. by Hiroaki Yoshikawa (4615801)

“…</p><p>Results</p><p>Our analysis revealed a significantly older age of onset in the 2018 cohort compared to 2006. …”