Table 4_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx by Maria Jordan (10265489)

“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”

Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx by Maria Jordan (10265489)

“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”

Table 4_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx by Wang Yu (8537490)

“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”

Table 2_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.docx by Wang Yu (8537490)

“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”

Table 1_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx by Wang Yu (8537490)

“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”

Table 3_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx by Wang Yu (8537490)

“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”

Image_2_Study of epirubicin sustained–release chemoablation in tumor suppression and tumor microenvironment remodeling.jpeg by Liangliang Meng (9500122)

“…On day 4 after local injection of the EPI gel, the expression of PD-L1 in abscopal tumors was upregulated, while the expression of PD-L1 in bilateral tumors in mice was significantly reduced after anti-PD-L1 treatment. The proportion of CD3⁺CD8⁺PD-1⁺ cells in the tumor and circulating blood in the EPI-GEL/PD-L1 group was decreased compared with that in the EPI-GEL (single injection of epirubicin) group.…”

Image_1_Study of epirubicin sustained–release chemoablation in tumor suppression and tumor microenvironment remodeling.jpeg by Liangliang Meng (9500122)

“…On day 4 after local injection of the EPI gel, the expression of PD-L1 in abscopal tumors was upregulated, while the expression of PD-L1 in bilateral tumors in mice was significantly reduced after anti-PD-L1 treatment. The proportion of CD3⁺CD8⁺PD-1⁺ cells in the tumor and circulating blood in the EPI-GEL/PD-L1 group was decreased compared with that in the EPI-GEL (single injection of epirubicin) group.…”

Neurochemical identity of dFB^23E10Ո^84C10 neurons. by Joseph D. Jones (13883524)

“…<b>(P)</b> Box plots of total sleep change in % ((total sleep on activation day-total sleep on baseline day/total sleep on baseline day) × 100) for control (<i>Empty-Split>Shi</i>^<i>ts1</i>), <i>VGlut-AD; 84C10-DBD>Shi</i>^<i>ts1</i> and <i>84C10-AD; ChAT-DBD>Shi</i>^<i>ts1</i> female flies. A Kruskal–Wallis ANOVA followed by Dunn’s multiple comparisons revealed that acutely silencing VGlut-AD; 84C10-DBD and 84C10-AD; ChAT-DBD neurons significantly decreases sleep. …”

<b>Seizure-induced changes in cytokine expression and dysregulation of plasminogen activation and IGF systems following kainic acid administration in rats</b> by Elena Suleymanova (22195777)

“…<p dir="ltr">Excessive neuronal activity during epileptic seizures initiates a cascade of pathological processes. Seizures alter the expression of numerous proteins, including pro- and anti-inflammatory cytokines, growth factors, chemokines, and proteolytic enzymes. …”

<i>Tg</i>ATM1-depleted <i>Toxoplasma</i> are functionally complemented through expression of the <i>Plasmodium</i> or yeast homolog. by Deepti Shrivastava (17715780)

“…IFAs were stained with anti-myc antibody, as well as antibodies against a mitochondrial marker, mitochondrial heat shock protein (mHSP70). …”

Effects of efgartigimod treatment on humoral and cellular immune responses: analysis of T-cell-dependent antibody response in cynomolgus monkeys by Ornella Binazon (20718978)

“…No statistically significant differences emerged in anti-KLH IgM levels between the efgartigimod and control groups. …”

DataSheet1_CircFOXO3 upregulation mediates the radioresistance of glioblastoma by affecting cellular metabolome.DOCX by Hao Xu (6530)

“…Introduction<p>Radioresistance remains a significant challenge in the treatment of glioblastoma multiforme (GBM), the most prevalent and lethal brain cancer in adults. …”

Table1_CircFOXO3 upregulation mediates the radioresistance of glioblastoma by affecting cellular metabolome.XLSX by Hao Xu (6530)

“…Introduction<p>Radioresistance remains a significant challenge in the treatment of glioblastoma multiforme (GBM), the most prevalent and lethal brain cancer in adults. …”

Image1_Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway induction.tif by Soon-Young Lee (4721136)

“…The incidence is expected to increase as the average life expectancy increases, highlighting asthma as a significant health challenge in an aging society. …”

Data Sheet 1_Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity.pdf by Vidushi Tyagi (14022240)

“…Andrographis paniculata, a plant used in traditional medicine, is known for its anti-inflammatory and immune-modulating properties, making it a promising candidate for treating gut-related conditions.…”

Data Sheet 1_Flaxseed intervention and reproductive endocrine profiles in patients with polycystic ovary syndrome: an open-labeled randomized controlled clinical trial.pdf by Zahra Najdgholami (21009269)

“…</p>Results<p>After 12 weeks, the flaxseed group showed a significant increase in FSH levels compared to the control group. …”

Table 1_Lactobacillus plantarum SAL delays aging-associated oxidative stress and gut microbiota dysbiosis in mice.doc by Wen Dong (467988)

“…These findings demonstrate the potential of L. plantarum SAL as an anti-aging probiotic and establish a theoretical framework for microbiota - targeted interventions to alleviate age-related pathologies.…”

Table 6_Immunosuppression of spleen in mice treated with erythropoietin: transcriptomic and immunological analysis.xlsx by Xinyi Lyu (14756739)

“…IHF and FCM validated that, at the cellular level, T, B, M1 cells were significantly reduced, and M2 cells were significantly decreased after EPO treatment. …”