يعرض 1,221 - 1,240 نتائج من 1,327 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant ((anti decrease) OR (a decrease)) ))~', وقت الاستعلام: 0.45s تنقيح النتائج
  1. 1221

    Data Sheet 1_Bryostatin-1 enhances the proliferation and functionality of exhausted CD8+ T cells by upregulating MAP Kinase 11.docx حسب Ling Li (38566)

    منشور في 2025
    "…Introduction<p>Bryostatin-1, a potent agonist of the protein kinase C, has been studied for HIV and cancer therapies. …"
  2. 1222

    Table 1_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx حسب Yue Bu (11357379)

    منشور في 2025
    "…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …"
  3. 1223

    Table 2_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx حسب Yue Bu (11357379)

    منشور في 2025
    "…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …"
  4. 1224

    Table 3_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.docx حسب Yue Bu (11357379)

    منشور في 2025
    "…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …"
  5. 1225

    Impact of acute binge-like ethanol exposure during the third-trimester equivalent on subicular interneurons in mice حسب Katalina M. Lopez (21821714)

    منشور في 2025
    "…Ethanol exposure decreased instantaneous frequency evoked by 250–400 pA current injection in fast-spiking GABAergic interneurons only in female mice (250: <i>p</i> = .019, g = −1.08; 300–450: <i>p</i> = .038, g = −1.06 to- 1.18) but did not significantly affect spontaneous inhibitory postsynaptic currents (sIPSCs) evoked by interneuronal GABA release onto pyramidal neurons.…"
  6. 1226

    Alternative therapeutic strategy for existing aortic aneurysms using mesenchymal stem cell–derived exosomes حسب Motoshi Kozakai (22435636)

    منشور في 2025
    "…</p> <p>MSC-ex might be a novel alternative therapeutic tool for treatment of existing AAs.…"
  7. 1227

    Data Sheet 1_Diethyl butylmalonate attenuates cognitive deficits and depression in 5×FAD mice.docx حسب Lai Yuan (20136422)

    منشور في 2024
    "…Diethyl butylmalonate (DBM) has recently attracted extensive interest due to its anti-inflammatory role in macrophages. However, it is still unknown whether DBM has a beneficial effect on cognitive deficits and depression.…"
  8. 1228

    Supplementary Material for: Hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-promoted PI3K-Akt signaling pathway حسب Zhan Y. (4157410)

    منشور في 2024
    "…Results: The biomarkers of microglia M1 polarization and pro-inflammatory cytokines were significantly increased in hypothyroidism mice brain; hypothyroidism could also repress the expression of BDNF and TrkB, and the anti-inflammatory cytokine such as IL-10. …"
  9. 1229
  10. 1230

    Candidate genes by Genome-wide CRISPR Screen. حسب Mingyi Xu (5575871)

    منشور في 2024
    "…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …"
  11. 1231

    DataSheet1_Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model.docx حسب Yuhan Zhang (2792089)

    منشور في 2024
    "…Dipeptide alanine-glutamine (Ala-Gln) is widely used as a nutritional supplement in the clinic and has anti-inflammatory effects on the gastrointestinal system. …"
  12. 1232

    Table 1_Microwave ablation triggers OX40L-mediated disruption of TNFRSF4+ Treg immunosuppressive activity.docx حسب Runqi Guo (22481293)

    منشور في 2025
    "…In vivo, MWA reshaped the tumor microenvironment by significantly increasing the intratumoral CD8+/Treg ratio (P<0.001), indicating a shift toward an anti-tumor inflammatory state. …"
  13. 1233

    Image 1_Ruminococcus bromii-generated acetate alleviated Clonorchis sinensis-induced liver fibrosis in mice.jpeg حسب Chun Li (57810)

    منشور في 2025
    "…</p>Results<p>The abundance of R. bromii increased during the inflammatory stage of C. sinensis infection and decreased significantly during the fibrosis stage. …"
  14. 1234

    Image_3_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG حسب Bin Zhang (64682)

    منشور في 2025
    "…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
  15. 1235

    Image_2_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG حسب Bin Zhang (64682)

    منشور في 2025
    "…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
  16. 1236

    Image_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG حسب Bin Zhang (64682)

    منشور في 2025
    "…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
  17. 1237

    Data Sheet 1_Association of early aspirin use with 90-day mortality in patients with sepsis: an PSM analysis of the MIMIC-IV database.docx حسب Chunsheng Huang (3222711)

    منشور في 2025
    "…</p>Conclusion<p>In conclusion, early aspirin use was associated with decreased in-hospital and 90-day mortality in septic patients, emphasizing the significance of early aspirin use administration in the ICU.…"
  18. 1238

    Image_4_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG حسب Bin Zhang (64682)

    منشور في 2025
    "…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
  19. 1239

    Table_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.XLSX حسب Bin Zhang (64682)

    منشور في 2025
    "…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
  20. 1240

    Presentation_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.pdf حسب Bin Zhang (64682)

    منشور في 2025
    "…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"