Data Sheet 1_Bryostatin-1 enhances the proliferation and functionality of exhausted CD8+ T cells by upregulating MAP Kinase 11.docx by Ling Li (38566)

“…Introduction<p>Bryostatin-1, a potent agonist of the protein kinase C, has been studied for HIV and cancer therapies. …”

Table 1_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx by Yue Bu (11357379)

“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”

Table 2_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx by Yue Bu (11357379)

“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”

Table 3_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.docx by Yue Bu (11357379)

“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”

Impact of acute binge-like ethanol exposure during the third-trimester equivalent on subicular interneurons in mice by Katalina M. Lopez (21821714)

“…Ethanol exposure decreased instantaneous frequency evoked by 250–400 pA current injection in fast-spiking GABAergic interneurons only in female mice (250: <i>p</i> = .019, g = −1.08; 300–450: <i>p</i> = .038, g = −1.06 to- 1.18) but did not significantly affect spontaneous inhibitory postsynaptic currents (sIPSCs) evoked by interneuronal GABA release onto pyramidal neurons.…”

Alternative therapeutic strategy for existing aortic aneurysms using mesenchymal stem cell–derived exosomes by Motoshi Kozakai (22435636)

“…</p> <p>MSC-ex might be a novel alternative therapeutic tool for treatment of existing AAs.…”

Data Sheet 1_Diethyl butylmalonate attenuates cognitive deficits and depression in 5×FAD mice.docx by Lai Yuan (20136422)

“…Diethyl butylmalonate (DBM) has recently attracted extensive interest due to its anti-inflammatory role in macrophages. However, it is still unknown whether DBM has a beneficial effect on cognitive deficits and depression.…”

Supplementary Material for: Hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-promoted PI3K-Akt signaling pathway by Zhan Y. (4157410)

“…Results: The biomarkers of microglia M1 polarization and pro-inflammatory cytokines were significantly increased in hypothyroidism mice brain; hypothyroidism could also repress the expression of BDNF and TrkB, and the anti-inflammatory cytokine such as IL-10. …”

Supplementary Material for: Association of platelet count and mean platelet volume with fish intake frequency: Implication for the cardioprotective effect of fish intake by figshare admin karger (2628495)

Candidate genes by Genome-wide CRISPR Screen. by Mingyi Xu (5575871)

“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”

DataSheet1_Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model.docx by Yuhan Zhang (2792089)

“…Dipeptide alanine-glutamine (Ala-Gln) is widely used as a nutritional supplement in the clinic and has anti-inflammatory effects on the gastrointestinal system. …”

Table 1_Microwave ablation triggers OX40L-mediated disruption of TNFRSF4+ Treg immunosuppressive activity.docx by Runqi Guo (22481293)

“…In vivo, MWA reshaped the tumor microenvironment by significantly increasing the intratumoral CD8+/Treg ratio (P<0.001), indicating a shift toward an anti-tumor inflammatory state. …”

Image 1_Ruminococcus bromii-generated acetate alleviated Clonorchis sinensis-induced liver fibrosis in mice.jpeg by Chun Li (57810)

“…</p>Results<p>The abundance of R. bromii increased during the inflammatory stage of C. sinensis infection and decreased significantly during the fibrosis stage. …”

Image_3_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”

Image_2_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”

Image_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”

Data Sheet 1_Association of early aspirin use with 90-day mortality in patients with sepsis: an PSM analysis of the MIMIC-IV database.docx by Chunsheng Huang (3222711)

“…</p>Conclusion<p>In conclusion, early aspirin use was associated with decreased in-hospital and 90-day mortality in septic patients, emphasizing the significance of early aspirin use administration in the ICU.…”

Image_4_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”

Table_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.XLSX by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”

Presentation_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.pdf by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”