Table 2_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx حسب Linling Du (22827035)

"…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"

Image 1_CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration.jpeg حسب Kexin Xu (757891)

"…</p>Results<p>CD3ζ knockdown significantly improved RGC survival by reducing apoptosis and necroptosis. …"

Data Sheet 1_Prognostic value of lymph node ratio in patients with non-small cell lung cancer: a systematic review and meta-analysis.zip حسب Junhuang Zheng (21629486)

"…</p>Results<p>This meta-analysis included 11 studies. High LNR was significantly associated with decreased overall survival (OS) (multivariable HR=1.76, 95% CI=1.36-2.27; univariable HR=2.26, 95% CI=1.95-2.63) and increased risk of shorter disease-free survival (DFS) (multivariable HR=1.66, 95% CI=1.48-1.88). …"

Image 6_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif حسب Ying Dong (41989)

"…</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …"

<b>Concurrent initiation of treadmill exercise protects against angiotensin II-induced renal injury by modulating oxidative stress and autophagy in mice</b> حسب Ji-Seok Kim (21287672)

"…The 4-week AngII group exhibited significantly increased fibrosis (~2-fold vs. Veh, p < 0.01), elevated TGF-β and iNOS expression, and disrupted autophagic flux, including increased LC3-II/I ratio and ATG expression, alongside decreased p62 levels. …"

DataSheet1_Enhancing resistant starch fraction in modified elephant foot yam starch: optimizing preparation conditions and exploring tribological properties.pdf حسب Sreejani Barua (13810723)

"…However, this retention decreased significantly to 1.08% after 10 min of cooking. …"

Table 1_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... حسب Minseo Kim (773205)

"…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"

Image 4_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation... حسب Todor Chobanov (22288636)

"…This approach revealed substantial Baltic genetic components in early Slavic populations (57% in Slovakia/Slovenia) decreasing to 39%–51% in medieval Croatian samples. …"

Table 5_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.docx حسب Yan Fan (575147)

"…This secretion was reinforced by the above sera. IGFBP5 decreased in ALI mice’s blood, while its supplement exacerbated inflammation. …"

Data Sheet 3_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx حسب Liqin Liang (652560)

"…Conversely, silencing the ortholog gene NbSOS1-13 in Nicotiana benthamiana showed more accumulation of ROS, serious cell necrosis, reduced activities of SOD and CAT, significantly increased MDA level, obvious leaf wilting, decreased tolerance to infection, and reduced leaf stomatal closure rate and accelerated stomatal area. …"

Graphic abstract of the study. حسب Donglin Yang (490406)

"…The results showed that the expression of circRNAs in serum exosomes of DN patients was significantly down-regulated, and hsa_circ_0006382 and hsa_circ_0019539 targeted the expression of FGF9 by binding to miR-34a-5p, miR-766-3p, miR-147a and miR-27a-3p. …"

Table 1_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx حسب Linling Du (22827035)

"…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"

Image 1_Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.tif حسب Yiping Cao (1229856)

"…Pharmacological activation of local PVT A_2AR with its agonist CGS21680 induced significantly decreased 50% paw withdrawal threshold (50%PWTs) and paw withdrawal latency (PWLs), as measured by the Von Frey test and Hargreaves test in adult mice. …"

Supplementary file 1_Parasite populations of river otter and mink in Western Canada, and the first report of the zoonotic trematode Alaria mustelae in river otter in North America.... حسب Kyle M. Shanebeck (21766418)

"…Increasing intensities of infection were significantly related to decreasing nutritional condition.…"

Image 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.tif حسب Miguel Ângelo-Dias (20936444)

"…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"

Table2_Slow-release boron fertilizer improves yield and nutritional profile of Beta vulgaris L. grown in Northeast China by increasing boron supply capacity.docx حسب Zhenzhen Wu (4747098)

"…Boron fertilizer can increase soil B content and significantly improve crop yield and quality. At present, the effects of slow-release B fertilizer on beet root yield and quality remain unclear. …"

Image 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.pdf حسب Mallory A. Perry-Eaddy (20842868)

"…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …"

Table 4_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... حسب Minseo Kim (773205)

"…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"

Data Sheet 1_Cohort analysis of high-risk HPV infection in adult women in Dapeng New District, Shenzhen, Guangdong Province, China.pdf حسب Weifeng Wei (1515805)

"…Large-scale HPV screening is crucial for early detection, as appropriate intervention in HPV-positive individuals can significantly reduce cervical cancer incidence and mortality.…"

Table 1_Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity.docx حسب Aihua Guo (13267712)

"…In addition, patients with high NOTCH1 expression showed decreased plasma cell infiltration in the microenvironment. …"