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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
based decrease » caused decreased (Expand Search), marked decrease (Expand Search), based defense (Expand Search)
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21361
Supplementary file 1_Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.docx
Published 2025“…Regionally, Southern Sub-Saharan Africa exhibited the highest prevalence, while Oceania and East Asia showed significant increases and decreases, respectively. Decomposition analysis of change in prevalence indicated that, globally, population contributed the most to changes in prevalence, followed by aging and epidemiological change. …”
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21362
Exploring cardiac vector propagation in acute myocardial infarction: a spatial velocity perspective
Published 2024“…There was no apparent alteration of SM in AMI.</p> <p>Decreased SV and SD without any significant alteration of SM indicates close approximation and clustering of the tips of the ventricular vector in AMI. …”
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21363
The association of piR-651 and piR-823 on metastatic and invasive characteristics of triple negative breast cancer cells
Published 2024“…The expressions of Ki-67, HIF-1α, MMP-2, and MMP-9 genes were measured at 48 h, when both cell lines exhibited the most significant effects of inhibition. The optimal time for proliferation of anti-piR-651 and anti-piR-823 transfected MDA-MB-231 cells was determined to be at 48 h, as indicated by decreased motility and invasion assay results (<i>p</i> < 0.001). …”
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21364
Supplementary file 2_Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.pdf
Published 2025“…Regionally, Southern Sub-Saharan Africa exhibited the highest prevalence, while Oceania and East Asia showed significant increases and decreases, respectively. Decomposition analysis of change in prevalence indicated that, globally, population contributed the most to changes in prevalence, followed by aging and epidemiological change. …”
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21365
Data Sheet 1_Plasma lipidomic alterations during pathogenic SIV infection with and without antiretroviral therapy.pdf
Published 2025“…</p>Results<p>Sphingomyelins (SM) and lactosylceramides (LCER) increased during acute infection, returning to baseline during chronic infection; Hexosylceramides (HCER) increased throughout infection, being normalized with prolonged ART; Phosphatidylinositols (PI) and lysophosphatidylcholines (LPC) decreased with SIV infection and did not return to normal with ART; Phosphatidylethanolamines (PE), lysophosphatidylethanolamines (LPE) and phosphatidylcholines (PC) were unchanged by SIV infection, yet significantly decreased throughout ART. …”
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21366
Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx
Published 2025“…Furthermore, the expression of silent information regulator 2(SIRT2) was down-regulated, while the expression of the G6PD protein just slightly increased in GBM cell lines. Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. …”
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21367
Table 1_Preventive administration of shengmaiyin: a novel approach to counteract heatstroke-induced coagulopathy in rats.xlsx
Published 2025“…The EHS group showed significantly prolonged PT and APTT, increased Lac, decreased platelet count, and elevated plasma levels of TM, vWF, TSP-1, and PAI-1 compared to the NC group (P < 0.05). …”
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21368
Table 2_Global, regional, and national burden of high body-mass index-related cancers and associated preventable life expectancy loss from 1990 to 2021.docx
Published 2025“…</p>Conclusion<p>The age-standardized mortality and DALY rates of cancer linked to high BMI have increased substantially, with significant differences across sex, geographic region, and SDI. …”
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21369
Harnessing genetic diversity in cotton for enhanced resilience against salt stress by using agro-physiological characters
Published 2024“…The general linear model analysis indicated significant salinity impacts across the studied accessions, and genotype × treatment effects were also significant for all parameters examined. …”
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21370
Table 4_Global, regional, and national burden of high body-mass index-related cancers and associated preventable life expectancy loss from 1990 to 2021.docx
Published 2025“…</p>Conclusion<p>The age-standardized mortality and DALY rates of cancer linked to high BMI have increased substantially, with significant differences across sex, geographic region, and SDI. …”
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21371
Table 2_R3HDM4 influences kidney renal clear cell carcinoma progression, immune modulation, and potential links to the IGSF8 immune checkpoint.docx
Published 2025“…Notably, silencing of R3HDM4 led to increased expression of Immunoglobulin Superfamily Member 8 (IGSF8).…”
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21372
Data Sheet 1_R3HDM4 influences kidney renal clear cell carcinoma progression, immune modulation, and potential links to the IGSF8 immune checkpoint.zip
Published 2025“…Notably, silencing of R3HDM4 led to increased expression of Immunoglobulin Superfamily Member 8 (IGSF8).…”
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21373
Table 1_Global, regional, and national burden of high body-mass index-related cancers and associated preventable life expectancy loss from 1990 to 2021.docx
Published 2025“…</p>Conclusion<p>The age-standardized mortality and DALY rates of cancer linked to high BMI have increased substantially, with significant differences across sex, geographic region, and SDI. …”
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21374
Table 6_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…MELC analysis further revealed a significantly increased ectocervical leukocyte population in HIV-seropositive participants, primarily driven by an increase in CD8<sup>+</sup> T cells while the CD4<sup>+</sup> T cell population remained stable. …”
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21375
Data Sheet 1_Integrated solutions for sustainable fall prevention in primary care: a pragmatic hybrid-type 2 mixed methods implementation and effectiveness study.pdf
Published 2024“…GPs in the experimental group were more likely to engage in fall prevention activities, including risk assessments, medication reviews, and providing advice, compared to the control group (p = 0.002). They were also more likely to refer patients to AHPs at 3 months (p = 0.002); however, this effect was not significant at 12 months (p = 0.13), as referral behaviors increased in the control group over time. …”
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21376
Table 4_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…MELC analysis further revealed a significantly increased ectocervical leukocyte population in HIV-seropositive participants, primarily driven by an increase in CD8<sup>+</sup> T cells while the CD4<sup>+</sup> T cell population remained stable. …”
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21377
Table 7_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…MELC analysis further revealed a significantly increased ectocervical leukocyte population in HIV-seropositive participants, primarily driven by an increase in CD8<sup>+</sup> T cells while the CD4<sup>+</sup> T cell population remained stable. …”
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21378
Image 1_Retrospective cohort study based on the MIMIC-IV database: analysis of factors influencing all-cause mortality at 30 days, 90 days, 1 year, and 3 years in patients with dif...
Published 2025“…Additionally, lower hemoglobin levels were significantly associated with increased mortality, with 30-day, 90-day, and 1-year mortality risks increasing by 3.33 times, 3.34 times, and 4.16 times, respectively (p < 0.005). …”
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21379
Table 1_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…MELC analysis further revealed a significantly increased ectocervical leukocyte population in HIV-seropositive participants, primarily driven by an increase in CD8<sup>+</sup> T cells while the CD4<sup>+</sup> T cell population remained stable. …”
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21380
Table 1_R3HDM4 influences kidney renal clear cell carcinoma progression, immune modulation, and potential links to the IGSF8 immune checkpoint.docx
Published 2025“…Notably, silencing of R3HDM4 led to increased expression of Immunoglobulin Superfamily Member 8 (IGSF8).…”