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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
based decrease » caused decreased (Expand Search), marked decrease (Expand Search)
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21021
Image 5_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.tif
Published 2025“…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …”
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21022
RNA quality photo
Published 2025“…Moreover, although the expression of the GRP78 gene increased in the sinus tissue of diabetic patients with mucormycosis, it significantly decreased in the same patients after treatment. …”
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21023
Presentation 1_CRIF1 gene therapy ameliorates inflammatory bowel disease by suppressing TH17 cells and fibrosis through mitochondrial function regulation.zip
Published 2025“…Patients with ulcerative colitis exhibited decreased CRIF1 levels with dysfunctional mitochondria in inflamed colonic tissue. …”
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21024
Supplementary Material for: Global, regional, and national burden of motor neuron disease: a systematic analysis of prevalence, incidence, deaths, and DALYs with projections to 203...
Published 2025“…Results: From 1990 to 2021, the global number of MND cases, deaths, and DALYs increased significantly, while the age - standardized prevalence and incidence rates decreased. …”
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21025
Image 6_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.jpeg
Published 2025“…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …”
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21026
Image 7_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg
Published 2025“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …”
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21027
Point Application Therapy Targeting Feishu, Pishu and Shenshu Attenuates Asthma by Suppressing Autophagy and the AMPK-mTOR Signalling Pathway
Published 2025“…The treatment additionally decreased expression levels of mTOR, LC3, NF-κB and TGF-β1 while increasing AMPK content. …”
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21028
Image 3_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg
Published 2025“…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”
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21029
Data Sheet 1_Early coronary angiography in patients with myocardial infarction without ST elevation after out-of-hospital cardiac arrest: a systematic review and meta-analysis.pdf
Published 2024“…Observational study subgroup showed decreased short-term mortality, long-term mortality, and CPC 1–2 at discharge, unlike RCT subgroup. …”
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21030
Supplementary file 1_Bioactive fraction isolated from Curcuma angustifolia rhizome exerts anti-diabetic effects in vitro, in silico and in vivo by regulating AMPK/PKA signaling pat...
Published 2025“…After 28 days of intervention, the lower and higher doses of the bioactive fraction (100 and 200 mg/kg BW) substantially decreased fasting blood glucose levels and ameliorated hyperglycemia, glucose intolerance, insulin resistance, and hyperlipidemia. …”
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21031
Data Sheet 1_Effect of cultivation feed diet using local food processing by-products on the growth and flavor factor in the Malabar grouper Epinephelus malabaricus.docx
Published 2025“…FW-D-fed fish also exhibited significantly increased muscle levels of unsaturated fatty acids, particularly docosahexaenoic acid (DHA), a nutrient beneficial for human health. …”
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21032
Data Sheet 1_Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats.docx
Published 2025“…</p>Results<p>Oral administration of TFEL for 13 weeks increased the serum level of bone formation marker PINP and decreased the level of bone resorption marker NTX-I. …”
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21033
Data Sheet 1_Polydopamine nanoparticles as immunomodulators: inhibition of M1 microglial polarization.docx
Published 2025“…To mimic neuroinflammatory conditions, HMC3 cells were stimulated with interferon-gamma (IFN-γ), which significantly increased intracellular ROS levels, surface expression of CD40 and CD86, and secretion of pro-inflammatory cytokines. …”
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21034
Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg
Published 2024“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”
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21035
DataSheet1_Effect of copper on nitrogen uptake, transportation, assimilation processes, and related gene expression in Chinese cabbage [Brassica campestris L. ssp. Chinensis (L.)]...
Published 2024“…Additionally, these effects were significantly modulated by the nitrate/ammonium ratios. …”
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21036
Image 4_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg
Published 2025“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …”
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21037
Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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21038
Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx
Published 2024“…The results showed that QWBZP-TG significantly altered the diversity, structure, and abundance of MAM in the AAD mice. …”
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21039
Table 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx
Published 2025“…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …”
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21040
Data Sheet 2_CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salinity conditions in quinoa.pdf
Published 2025“…By contrast, K<sup>+</sup> accumulation was slightly reduced in the aerial parts but significantly decreased in the roots of all the genotypes. …”