Showing 801 - 820 results of 6,066 for search '(( significant decrease decrease ) OR ( significant ((c decreased) OR (a decrease)) ))~', query time: 0.57s Refine Results
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    qPCR primer sequences. by Shuaini Yang (20670608)

    Published 2025
    “…Specifically, <i>ccr2</i> deficiency disrupts the differentiation and response of Th1 cells, which are the primary effector lineage responsible for clearing chlamydia through secretion of interferon-gamma (IFN-γ). As a result, there is a significant decrease in CD3<sup>+</sup>CD4<sup>+</sup>IFN-γ<sup>+</sup> T cells in the lung and spleen, accompanied by reduced levels of IFN-γ protein and mRNA, as well as downregulated mRNA expression of Th1-promoting cytokines (<i>il-12p35</i>, <i>il-12p40</i>) and transcription factors (<i>stat4</i>, <i>T-bet</i>), which play crucial roles in Th1 differentiation. …”
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