DataSheet1_Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters.PDF by Safaa Yehia Eid (17768736)

“…In MCF-7/ADR and MDA-MB-231/ADR cells, COP (31 μM) enhanced DOX cytotoxicity with CI (0.77 and 0.75), RR (2.58 and 3.33), and IB suggesting synergism. COP significantly inhibits ABCT function in resistant BC cell lines, increases Rho123 accumulation, and decreases efflux more than VER; 2.1 and 1.2-fold, respectively. …”

TNC promotes bone regeneration via inflammatory macrophage by Qian Ren (19955367)

“…Transplantation of macrophages derived from injured periosteum is able to rescue the decreased skeletal stem cells and impaired bone regeneration caused by TNC deficiency. …”

Epidural Hydromorphone for Postpartum Pain Management After Vaginal Delivery: A Randomized Clinical Trial by Yixing Lu (19234084)

“…</p><p><br></p><p dir="ltr"><b>Findings</b></p><p dir="ltr">Epidural hydromorphone demonstrated a statistically significant reduction in postpartum pain scores, a decreased requirement for supplemental analgesics, and enhanced maternal satisfaction. …”

Table 1_The impact of comorbidities on surgical outcome and mortality in minimally invasive mitral valve surgery: a systematic review.docx by Vanessa I. T. Zwaans (22163257)

“…Left atrial (LA) diameter decreased significantly from 50.37 mm preoperatively to 40.41%mm postoperatively (p < 0.001), LVDD was significantly reduced after MIMVS (p < 0.001). …”

Table 1_Stroke-associated pneumonia with low PaO2/FiO2 ratio in acute large vessel occlusion after endovascular therapy: risk factors and prognosis.docx by Kun Tang (75641)

“…A deterioration in SAP manifests itself in a decreased partial pressure oxygen (PaO₂)/fraction of inspired oxygen (FiO₂) ratio, indicating gas exchange dysfunction. …”

Figure 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal by Ángel Fernández-Sanromán (20814476)

“…Variables in blue and gray bars display significant (FDR < 0.05) and nonsignificant associations, respectively. …”

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation by Anna Rutkowska (19676837)

“…Niraparib decreases CYP51A1 (lanosterol 14α-demethylase) enzyme levels (Supplementary Fig. …”

Source data.zip by Xiaoyan Pan (21158717)

“…In vivo, melatonin significantly increased MT1R (melatonin receptor 1A) expression in BPA-treated mouse testicular cells and the content of catalase, superoxide dismutase 2, and glutathione, while decreasing the level of malondialdehyde. …”

Image 2_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Table 1_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.xlsx by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Image 1_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Image 4_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Image 5_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tif by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Image 3_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Supplementary Material for: High serum phosphate promotes cognitive impairment in uremia rats via mediating vascular calcification by figshare admin karger (2628495)

“…Results: The results showed that both the learning and memory abilities and the spatial exploration ability of the rats in Uremia + Pi group were significantly decreased with enhanced expressions of ALP and Runx2, calcium content and ALP activity, however, STP supplementation significantly alleviated the spatial learning and memory damage, reduced the ALP and Runx2 expressions, calcium content and ALP activity. …”

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF by Huan Yu (140826)

“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF by Huan Yu (140826)

“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”

Data Sheet 1_Global, regional, and national burden of ischemic heart disease attributed to non-optimal temperature, 1990–2021: an age-period-cohort analysis of the global burden of... by Xiaoqing Xia (14607269)

“…</p>Conclusions<p>The IHD burden caused by non-optimal temperature significantly varied according to the genders, SDI regions, and countries from 1990 to 2021. …”

<b>Selective Reduction of Ca</b>^{<strong>2+</strong>}<b>-Independent Phospholipase A</b>_{<strong>2</strong>}<b>b</b><b> (iPLA</b>_{<strong>2</strong>}<b>b... by Abdulaziz Almutairi (9584768)

“…</p><p dir="ltr">· Reduction of myeloid-iPLA₂b decreases T1D incidence.</p><p dir="ltr"><br><b>d. …”

Table 1_Immunoglobulin G N-Glycome as a biomarker of mortality risk in Escherichia coli induced sepsis.docx by Huachen Wang (11272203)

“…</p>Results<p>We identified that the fucosylation level was significantly decreased in patients. Importantly, bisecting GlcNAc, sialylation, and galactosylation have different levels between sepsis and control groups. …”