Image 5_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…This quantification was also performed in HGFs with suppressed Cav-1 expression using western blotting.</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Table 1_CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway.docx by Liubing Hou (10888140)

“…Background<p>Radioresistance poses a major therapeutic challenge in ESCC, significantly impacting patient prognosis. CD9, as a crucial membrane regulatory protein, exhibits dual regulatory roles in various cancers, yet its precise mechanism in ESCC radioresistance remains unclear. …”

Table 1_Uniaxial tensile material properties of adult Chinese dura mater: investigating the influence of age, sex, and anatomical site.docx by Jinming Wang (191356)

“…</p>Results<p>indicated significant age-related degradation: E_C, σ_Tf, ε_Tf; and MaxForce significantly decreased with age (median E_C declined from 28.0 MPa in young adults to 15.3 MPa in the elderly, P < 0.05; median ε_Tf from 0.215 to 0.156, P < 0.05), while E_E showed no significant age correlation (P = 0.10). …”

Table 1_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Data Sheet 4_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Data Sheet 1_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Data Sheet 1_Eupalinolide A inhibits cancer progression and induces ferroptosis and apoptosis by targeting the AMPK/mTOR/SCD1 signalling in non-small cell lung cancer.docx by Yonghui Zhang (279832)

“…EA treatment (25 mg/kg) markedly inhibited tumour growth in vivo in a xenograft model; both tumour weight and tumour volume decreased by more than 60% without significantly affecting the body weight of tumour-bearing mice.…”

Data Sheet 3_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Table 3_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Table 4_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Table 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Data Sheet 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Video 1_Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.mp4 by Arijit Ghosh (1304952)

“…Overexpression of kininogen and exogenous bradykinin administration significantly increased pentylenetetrazole-induced seizure susceptibility in mice. …”

Table 5_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Postoperative complications and mortality [n(%)]. by Qingwen Cao (22439195)

“…The proportion of patients with American Society of Anesthesiologists (ASA) ≥ III, Nottingham hip fracture score (NHFS) ≥ 5 and preoperative activity tolerance < 4 metabolic equivalents (METs) increased sequentially (<i><i>P</i> </i>< 0.001), across the YO, MO, and OO groups, whereas the proportion of those with three or more internal medicine comorbidities sequentially decreased (<i><i>P</i> </i>< 0.001). All three groups were primarily injured by falls and the older the age, the higher the proportion of injuries caused by falls (<i><i>P</i> </i>= 0.006). …”

Information of surgery and anesthesia [n(%)]. by Qingwen Cao (22439195)

“…The proportion of patients with American Society of Anesthesiologists (ASA) ≥ III, Nottingham hip fracture score (NHFS) ≥ 5 and preoperative activity tolerance < 4 metabolic equivalents (METs) increased sequentially (<i><i>P</i> </i>< 0.001), across the YO, MO, and OO groups, whereas the proportion of those with three or more internal medicine comorbidities sequentially decreased (<i><i>P</i> </i>< 0.001). All three groups were primarily injured by falls and the older the age, the higher the proportion of injuries caused by falls (<i><i>P</i> </i>= 0.006). …”

Raw data. by Qingwen Cao (22439195)

“…The proportion of patients with American Society of Anesthesiologists (ASA) ≥ III, Nottingham hip fracture score (NHFS) ≥ 5 and preoperative activity tolerance < 4 metabolic equivalents (METs) increased sequentially (<i><i>P</i> </i>< 0.001), across the YO, MO, and OO groups, whereas the proportion of those with three or more internal medicine comorbidities sequentially decreased (<i><i>P</i> </i>< 0.001). All three groups were primarily injured by falls and the older the age, the higher the proportion of injuries caused by falls (<i><i>P</i> </i>= 0.006). …”

Additional file 2 of Single-cell profiling reveals periosteal signatures of impaired periosteal cells proliferation in a drill-hole model of type 2 diabetes by Xing Ji (3096735)

“…RT-qPCR results showing the mRNA levels of Raptor following knockout using CRISPR-Cas9 lentivirus. Statistical significance was determined using a two-tailed Student’s t-test. …”

Robust chain-length specific reductions in some intermediate chain and long chain PE phospholipids in peroxisomal mutant brain. by Michael F. Wangler (21526595)

“…</b> Levels in mol% of PE 33:3 in <i>pex2</i> and <i>pex16</i> mutant brains show significant decreases in <i>pex</i> mutant brains. For PE 33:3 in <i>pex2</i>² brain and <i>pex2</i>^<i>1</i> brain, levels are dramatically reduced compared to controls (ratio 0.225, 0.200 respectively, p < 0.001, p < 0.001 respectively) and <i>pex2</i>^<i>2</i> brain compared to rescue (ratio 0.244, p < 0.001), and <i>pex2</i>^<i>1</i> compared to rescue (ratio 0.220, p < 0.001). …”

Image 6_Study on the ecosystem service flow based on the relationship of between supply and demand in Yangtze River Economic Belt.jpeg by Ming Lei (161082)

“…From 2015 to 2020, the number of areas with balanced supply and demand of ecosystem services in the Yangtze River Economic Belt decreases and the number of areas with unbalanced supply and demand increases, which is related to the changes in the level of economic development and land use patterns. 3). …”