Data Sheet 8_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf by Meizhi Liu (21898892)

“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”

Subcellular localization and protein level of APC in wild type and <i>Cep290</i> KO cells. by Kazuhiko Matsuo (2880248)

“…Note that fluorescence intensity of APC at the leading edge was significantly decreased in <i>Cep290</i> KO cells. (C) Protein expression levels in wild type and <i>Cep290</i> KO cells were assessed by Western blotting. …”

CircFNDC3B inhibits vascular smooth muscle cells proliferation in abdominal aortic aneurysms by targeting the miR-1270/PDCD10 axis by Baoping Deng (9081380)

“…</i> Our findings revealed a significant upregulation of circFNDC3B expression in AAA clinical specimens compared to normal tissues. …”

Table 1_Eculizumab for the acute attack of neuromyelitis optica spectrum disorder.docx by Qingqing Zhuang (22109089)

“…Following eculizumab, six of the seven ON patients showed significant improvements in visual acuity and visual fields, with five recovering to near-normal or pre-attack vision. …”

Data Sheet 1_Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and... by Dilpreet Kour (10872766)

“…IBC-treated astrocytes exhibited significant clearance of extracellular amyloid beta. …”

Data Sheet 1_Role of intercellular interactions on single cell and population level responses: considerations for multicellular bioreporter design.docx by Douglas Lin (10309772)

“…</p>Results<p>Simulations for 20 s of simulated time show that while final reporter protein count per cell decreased as cell count increased, aggregate final reporter protein number across all cells significantly increased. …”

DataSheet1_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.docx by Xiaoqin Zhang (517854)

“…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …”

Data Sheet 1_Application of chlorous acid water for disinfection of surgical site in dairy cows.pdf by Osamu Ichii (339354)

“…The cleansing procedure significantly reduced the SPCB, EF, and SP on the skin after clipping, and all disinfection methods significantly decreased the SP after cleansing. …”

Table 7_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx by Yanyao Lu (22163632)

“…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …”

Image 3_The role of PCBP1 in carbon ion-induced ferroptosis and inhibition of lung adenocarcinoma proliferation.tif by Zhenchao Kang (20523974)

“…</p>Results<p>Carbon ions significantly inhibited the proliferation of A549 cells, and 5.16 Gy carbon ions significantly induced the expression of differentially expressed genes in these cells. …”

Data Sheet 1_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Data Sheet 1_Distalization of the mandibular first molar with clear aligners: a 3D finite element study.docx by Fujia Kang (20110209)

“…For the second molar, the most significant mesial displacement was observed in the second molar ATT group.…”

Raman spectra (a) GNPs, and (b) Ag nanoparticles. by Athirah Najwa Zaaba (22559957)

“…Higher nanoparticle loadings improved conductivity further but caused significant viscosity increases and reduced stability. …”

Neural lamella remodeling is needed for macrophage invasion. by Bente Winkler (20760273)

“…(<b>C</b>) Panglial expression of <i>Pvf2</i> and concomitant knockdown of <i>STAT92E</i> decreases the number of invaded macrophages by ~ 10-fold. …”

Analysis diagram of economic carrying system. by Hui Li (32376)

“…Our results indicate significant changes in land types within the TGRR from 1986 to 2020, with decreases in arable land, forest land, and grassland, while water bodies, building land, and unused land increased. …”

Analysis diagram of population carrying system. by Hui Li (32376)

“…Our results indicate significant changes in land types within the TGRR from 1986 to 2020, with decreases in arable land, forest land, and grassland, while water bodies, building land, and unused land increased. …”

Data Sheet 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.pdf by Shuangmei Zhang (1807303)

“…</p>Results<p>By week 24, secukinumab treatment led to significant reductions in disease severity scores (QMG: 60.7%; MG-QOL15: 58.3%; MG-ADL: 64.1%) and AChR antibody levels (69.23%). …”

Data Sheet 1_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind... by Yanping Wang (275956)

“…Additionally, HLTP reversed 63 CUMS-induced abnormal serum metabolites, primarily affecting tryptophan metabolism, niacin and nicotinamide metabolism, and porphyrin metabolism. Significant correlations were observed among gut microbial composition, serum metabolite levels, biochemical indices, and behavioral outcomes.…”

Global, regional and national trends in burden of chronic obstructive pulmonary disease (COPD) from 2000 to 2021 and the prediction for 2030: An analysis of the Global Burden of Di... by Huiqing Xu (20467802)

“…However, ASRs of incidence, prevalence, deaths and DALYs decreased, and, moreover, such a declining trend would continue to 2030. …”

Image_3_Effect of probiotic supplementation combined with bismuth-containing quadruple therapy on gut microbiota during Helicobacter pylori eradication: a randomized, double-blind,... by Zhongxue Han (19855215)

“…After treatment, the GSRS score decreased significantly in the probiotic group (p = 0.039). …”