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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
challenges decrease » challenges case (Expand Search)
challenges pose » challenges posed (Expand Search), challenges due (Expand Search), challenges p (Expand Search)
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21001
Table 7_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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21002
Supplementary file 1_Forced intensity-controlled endurance training on a small-animal treadmill machine inducing murine cardiac hypertrophy: insights and comparison to voluntary ru...
Published 2025“…<p>Endurance training is associated with decreased cardiovascular-related morbidity and mortality. …”
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21003
Dependent and independent variables (N = 316).
Published 2025“…<div><p>Introduction</p><p>Unmet oral health needs remain a significant issue among immigrant adolescents, often exacerbated by experiences of racial discrimination. …”
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21004
Image 1_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
Published 2025“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”
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21005
DataSheet2_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf
Published 2024“…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…”
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21006
Supplementary file 1_Emergency department overcrowding: first Swiss application of the Emergency Department Work Index and risk factors for overcrowding.pdf
Published 2025“…Introduction<p>Emergency department (ED) overcrowding is associated with increased waiting time, reduced patient satisfaction, and decreased quality of care. Numerous validated scores are available for assessing ED overcrowding. …”
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21007
Dataset with steel insert.
Published 2024“…It focuses on identifying and quantifying clinically significant materials in the presence of metal objects. …”
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21008
Table 2_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.xlsx
Published 2025“…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …”
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21009
Image 1_Lower hippocampal volumes at baseline are associated with higher volume loss in healthy elderly.png
Published 2025“…No covariates significantly influenced this association (p > 0.05).…”
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21010
Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx
Published 2025“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”
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21011
Reference dataset.
Published 2024“…It focuses on identifying and quantifying clinically significant materials in the presence of metal objects. …”
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21012
Data Sheet 1_Increased circulating levels of SP-D and IL-10 are associated with the development of disease severity and pulmonary fibrosis in patients with COVID-19.pdf
Published 2025“…Among the biomarkers indicative of macrophage polarization, compared to non-ARDS patients, a significant increase in IL-10, Inducible nitric oxide synthase (iNOS), and Arginase-1 (Arg-1) were observed in ARDS patients, while Tumor necrosis factor-α (TNF-α) was decreased. …”
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21013
Data Sheet 1_Association of cardiovascular health with COPD (NHANES 2007-2020): mediating potential of lean body mass.docx
Published 2025“…</p>Conclusions<p>Higher LC9 scores, particularly when accompanied by increased LBM levels, showed significant associations with reduced COPD risk in cross-sectional analyses.…”
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21014
Supplementary file 1_Evaluation of drug interactions in outpatients taking antipsychotic medications.docx
Published 2025“…The most frequent potential adverse effects were increased sedation (36%), hyperglycemia (15%) and decreased blood pressure (14%). Receiving polypharmacy (i.e., ≥5 drugs concomitantly administered) was significantly associated with an increased probability of drug interaction occurrence (OR = 42, P = 0.0026). …”
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21015
Table 1_Lactobacillus plantarum SAL delays aging-associated oxidative stress and gut microbiota dysbiosis in mice.doc
Published 2025“…Gut microbiota analysis revealed increased abundances of Firmicutes and Verrucomicrobia, decreased Bacteroidetes, and elevated Firmicutes/Bacteroidetes (F/B) ratio (p < 0.05). …”
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21016
Data Sheet 2_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont...
Published 2025“…Adding TXL to WM showed a non-significant trend toward reducing myocardial infarction [RR 0.34, 95% CI (0.05, 2.12); NNT = 41] and sudden cardiac death [RR 0.34, 95% CI (0.01, 8.28); NNT = 65]. …”
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21017
Table2_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx
Published 2024“…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …”
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21018
Yeast strains used in this study.
Published 2025“…Furthermore, as H2A.Z mutants only display significant growth defects in genotoxic stress conditions, a more substantive role for H2A.Z in gene expression may only be uncovered after exposure to cellular stress. …”
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21019
Table 1_Trend analysis of pediatric urolithiasis prevalence from 1990 to 2021 in the BRICS.docx
Published 2025“…Finally, China has made significant progress in the prevention and control of pediatric urolithiasis over the past 30 years and is expected to continue this positive trend over the next 15 years.…”
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21020
Counting results on MTDC-UAV dataset.
Published 2024“…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …”