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19361
Data Sheet 1_Methylglyoxal induces oxidative stress and ferroptosis of renal tubular epithelial cells in acute and chronic kidney injury mice.docx
Published 2025“…MG promotes advanced glycation end product (AGE) formation and directly impairs cell function. MG levels are significantly increased in various renal diseases. This study aimed to investigate the relationship between MG and ferroptosis, which is a form of cell death involving iron-dependent lipid peroxidation (LPO), during kidney injury. …”
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19362
Table 1_Mechanism of action of decitabine in treating acute lymphoblastic leukemia.docx
Published 2025“…Animal experimental results indicated that both DAC and doxorubicin substantially decreased tumor length, width, volume, and mass; however, DAC demonstrated significantly superior efficacy in inhibiting tumor growth compared to doxorubicin.…”
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19363
Image 1_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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19364
Table 2_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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19365
Supplementary file 1_Resting-state EEG alterations and cognitive impairment in atrial fibrillation: insights into neural biomarkers and functional connectivity.docx
Published 2025“…</p>Results<p>AF patients had significantly lower MoCA scores. PSD analysis showed increased δ and θ and decreased α and β activity. …”
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19366
The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence
Published 2025“…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii </i>by quantitative real-time PCR (RT-qPCR) analyses. …”
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19367
Table 4_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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19368
Supplementary Material for: A selenium disulfide-based shampoo is beneficial for dandruff management and rebalancing the scalp microbiome of subjects of any hair type
Published 2025“…After 4 weeks, signs and subject assessments had significantly (all p<0.05) decreased. SeS2 shampoo significantly (p<0.001) rebalanced the scalp microbiome. …”
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19369
Table 3_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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19370
Table 1_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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19371
Data Sheet 1_Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease.docx
Published 2025“…In contrast, the reverse MR analysis found that Parkinson’s disease susceptibility significantly increased dopamine 3-O-sulfate levels.</p>Conclusion<p>The differential expression of CSF metabolites reveals early cellular metabolic changes, providing insights for early diagnosis and monitoring PD progression. …”
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19372
Table 5_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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19373
Data Sheet 1_Lysate of Parabacteroides distasonis prevents severe forms of experimental autoimmune encephalomyelitis by modulating the priming of T cell response.docx
Published 2024“…Pd lysate significantly delayed the development of EAE and reduced its severity when administered prior to disease induction. …”
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19374
Molecular features influencing clinical outcome of advanced HER2-positive gastric cancer receiving trastuzumab plus chemotherapy
Published 2025“…Additionally, after treatment, TMB significantly increased in non-responders, while CIN significantly decreased in responders.…”
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19375
Supplementary file 1_Effects of human urine application on soil physicochemical properties, microbial communities, and enzymatic activities.docx
Published 2025“…<p>Human urine (HU) is rich in nutrients necessary for plant growth, and recycling HU as fertilizer has multiple positive impacts, such as enhancing agricultural sustainability, reducing wastewater pollution, and decreasing reliance on chemical fertilizers, so it is of great significance to explore the effects of urine agricultural utilization on soil environment. …”
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19376
Data_Sheet_1_Copper pyrazole addition regulates soil mineral nitrogen turnover by mediating microbial traits.pdf
Published 2024“…The soil NH4+-N content peaked on the 10th day and was significantly greater in UC compared to U, while the NO3−-N content was significantly greater in U compared to UC on the 60th day. …”
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19377
Table 1_The relationship between positive future thinking, entrapment, defeat and death-related mental imagery in individuals with and without a suicidal history: an experimental s...
Published 2025“…Mean scores for PFT from pre-to post-negative mood induction decreased significantly in the participants with a history of suicidal thoughts/behaviours but not in those without a suicidal history. …”
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19378
Data Sheet 1_Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota.docx
Published 2025“…After baicalein treatment, the proinflammatory cytokines (TNF-α, IL-1β), and anti-inflammatory cytokine (IL-10) has decreased. Additionally, high-dose of baicalein strongly reversed oxidative stress alterations caused by DSS, as evidenced by Fe<sup>2+</sup>, MDA, ROS significantly depleted, and MPO, SOD, GSH significantly increased. …”
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19379
Image 2_Modulation of fenestrated vasculature in the median eminence and area postrema in response to neurotoxin exposure and its impairment in aging.tif
Published 2025“…Upon MSG exposure, fenestrated capillaries and vascular permeability were decreased in the ME but increased in the AP, and these changes were closely associated with the expression of angiogenic factors pleiotrophin (Ptn) and vascular endothelial growth factor A (Vegfa). …”
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19380
Image 1_Modulation of fenestrated vasculature in the median eminence and area postrema in response to neurotoxin exposure and its impairment in aging.tif
Published 2025“…Upon MSG exposure, fenestrated capillaries and vascular permeability were decreased in the ME but increased in the AP, and these changes were closely associated with the expression of angiogenic factors pleiotrophin (Ptn) and vascular endothelial growth factor A (Vegfa). …”