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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
changes decrease » larger decrease (Expand Search), largest decrease (Expand Search)
change increases » large increases (Expand Search), shape increases (Expand Search), range increase (Expand Search)
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20201
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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20202
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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20203
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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20204
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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20205
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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20206
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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20207
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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20208
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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20209
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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20210
DataSheet1_Semen Cuscutae flavonoids activated the cAMP-PKA-CREB-BDNF pathway and exerted an antidepressant effect in mice.docx
Published 2024“…</p>Results<p>SCFs resulted in significant increases in both body weight and food intake and in the amelioration of the depressive-like behaviors in CUMS mice. …”
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20211
Table 1_Relationship between nocturia, depression, and cognitive function and the mediating effects of nutritional indexes in older adults: data from NHANES 2011–2014.docx
Published 2025“…Thus, improving nutrition may decrease the risk of nocturia in older adults.</p>…”
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20212
Table 1_Molecular hybridization modification improves the stability and immunomodulatory activity of TP5 peptide.docx
Published 2024“…The half-life of YTP in plasma is significantly longer than that of YW12D and TP5. YTP also displays an improved ability to protect the host from CTX-induced weight loss and thymus and spleen indices decrease than YW12D and TP5. …”
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20213
Table 1_Moso bamboo invasion alters soil microbial nutrient limitation by modifying plant diversity and soil nutrient cycling in subtropical forest.docx
Published 2025“…</p>Results<p>Results showed that bamboo invasion reduced overstory (tree layer) diversity but increased diversity in the shrub and herb layers. Soil total organic carbon (TOC), total nitrogen (TN), available phosphorus (AP), and available potassium (AK) all decreased significantly with increasing invasion intensity. …”
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20214
Table 3_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.xlsx
Published 2025“…Projections indicate a continued decline in AVH burden by 2031, driven by population dynamics and epidemiological changes.</p>Conclusion<p>While global AVH burden is decreasing, significant disparities persist, warranting tailored interventions to enhance resource equity in high-SDI regions and strengthen healthcare infrastructure in low-SDI areas.…”
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20215
Table 2_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.xlsx
Published 2025“…Projections indicate a continued decline in AVH burden by 2031, driven by population dynamics and epidemiological changes.</p>Conclusion<p>While global AVH burden is decreasing, significant disparities persist, warranting tailored interventions to enhance resource equity in high-SDI regions and strengthen healthcare infrastructure in low-SDI areas.…”
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20216
Supplementary file 1_Clinical utility of the PBAC score in quantifying treatment response to hysteroscopy: a retrospective observational study.docx
Published 2025“…Data were analyzed using SPSS version 26, and p < 0.05 was considered statistically significant.</p>Results<p>Of the 327 patients included in the study, 91.1% had a baseline PBAC score ≥100, which significantly decreased following hysteroscopy (mean reduction: 393 points; p < .001). …”
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20217
Data Sheet 1_Crop rotation complexity affects soil properties shaping antibiotic resistance gene types and resistance mechanisms.docx
Published 2025“…Our findings revealed that soil properties varied significantly with crop rotation regime and complexity. …”
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20218
Table 1_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.docx
Published 2025“…Projections indicate a continued decline in AVH burden by 2031, driven by population dynamics and epidemiological changes.</p>Conclusion<p>While global AVH burden is decreasing, significant disparities persist, warranting tailored interventions to enhance resource equity in high-SDI regions and strengthen healthcare infrastructure in low-SDI areas.…”
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20219
Data Sheet 1_The impact of landscape patterns on surface runoff in the central urban area of Chengdu.docx
Published 2025“…When the proportions of farmland and forestland were low, their effectiveness in reducing runoff decreased with increasing rainfall intensity. Similarly, the impact of impervious surfaces also diminished with increasing rainfall intensity. ④ The SSRLI demonstrated good applicability in predicting changes in surface runoff, showing a significant positive correlation with runoff depth. …”
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20220
Dynamic network effects of left DLPFC-tDCS protocol (F3a-Fp2c) with the stimulation duration of 120s (168 TRs).
Published 2025“…Warmer colors indicate an increase in FC, while cooler colors indicate a decrease in FC. Color bars indicate statistical t-values (<i>p</i> < 0.05).…”