Bioassay and NMR-HSQC-Guided Isolation and Identification of Phthalide Dimers with Anti-Inflammatory Activity from the Rhizomes of Angelica sinensis by Hongyan Wen (9226895)

“…Among them, compound <b>9</b> showed a remarkable inhibitory activity with IC₅₀ values of 425 nM and could significantly decrease IL-1β and IL-6 transcription levels. …”

Data_Sheet_1_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The deficits in hippocampal-dependent learning and memory were accompanied by altered hippocampal neurogenesis, with an overall decrease in the proliferation and differentiation of newborn neurons within the dentate gyrus. …”

Bioassay and NMR-HSQC-Guided Isolation and Identification of Phthalide Dimers with Anti-Inflammatory Activity from the Rhizomes of Angelica sinensis by Hongyan Wen (9226895)

“…Among them, compound <b>9</b> showed a remarkable inhibitory activity with IC₅₀ values of 425 nM and could significantly decrease IL-1β and IL-6 transcription levels. …”

Effects of Nitro-Substitution on the Spectroscopic and Self-Assembly Properties of BODIPY Dyes by Caroline Gwaro (21012411)

“…In a polar organic solvent, nitro-substitution tends to quench the characteristic fluorescence of BODIPYs, while in a nonpolar solvent, significantly higher absolute fluorescence quantum yields are observed. …”

Presentation_1_Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson’s Disease Models.PDF by Hanyu Yang (8374881)

“…The results showed that inhibition of Src could significantly relieve microgliosis and decrease levels of inflammatory factors. …”

OMT by Jingmin Ou (19669426)

“…<p dir="ltr">In this study, we performed a series of experiments to investigate the effects of oxymatrine (OMT) on hemangioma cells and its mechanisms. OMT was found to significantly increase the apoptosis rate of endothelial cells (ECs) treated with oxidised low-density lipoprotein (ox-LDL), as measured by caspase-3 activity assay and flow cytometry. qRT-PCR results showed that OMT treatment decreased the expression of miR-199a-5p in ECs.Transfection of miR-199a-5p mimics enhanced the apoptotic effect, whereas miR-199a-5p inhibitors attenuated apoptosis, suggesting that miR-199a-5p has a key regulatory role in EC apoptosis. …”

Data Sheet 1_A ROS-responsive, aptamer-targeted graphene oxide nanocomposite for site-specific glutathione release in cerebral ischemia-reperfusion injury.docx by Meiying Li (6051287)

“…In vitro, GO@GSH-FA significantly restored viability in oxygen-glucose-deprived SH-SY5Y cells (from 31% up to near control levels), reduced inflammatory cytokines, and lowered intracellular ROS. …”

DataSheet1_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

Data Sheet 1_Causal relationship between inflammatory bowel disease and sex: a Mendelian randomization study.pdf by Kaiwen Wang (838527)

“…</p>Results<p>There was no causal relationship between sex hormones and IBD in women (P > 0.05), and there was a causal and positive correlation between SHBG and testosterone and IBD in men.The OR for SHBG was 1.22 (95% CI: 1.09-1.37, P = 0.0004), and for testosterone was 1.20 (95% CI: 1.04-1.39, P = 0.0145).IBD did not significantly interact with female sex hormones but resulted in a decrease in SHBG (OR = 1.02, 95% CI: 1.00-1.04, P = 0.0195) and testosterone (OR = 1.01, 95% CI: 1.00 -1.02, P = 0.0200) in men.…”

A rapid behavioral toxicity test using common periwinkle <i>Littorina littorea</i> (Gastropoda: Littorinidae) by Bjørn Henrik Hansen (1636042)

“…The exposure resulted in a concentration-dependent decrease in active suction, with snails retracting into their shells, which significantly reduced their oxygen consumption, indicating avoidance behavior. …”

Data Sheet 1_Assessment of heat-killed E. coli expressing Chikungunya virus E2 protein as a candidate vaccine for dual protection against Chikungunya virus and E. coli.docx by Surajit Patra (18400578)

“…Similarly, the vaccine formulation also elicited a significantly higher IgG immune response against E. coli. …”

DataSheet2_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

HG module schematic. by Wenhao Ren (2561731)

“…These innovations significantly improve semantic segmentation accuracy while reducing computational overhead. …”

<i>E²GO</i>: Free Your Hands for Smartphone Interaction by Shaoming Yan (21339553)

“…We also integrated an event-triggering mechanism in <math><mrow><mrow><mi>E</mi></mrow><mn>2</mn>GO</mrow></math> to significantly decrease its power consumption to deploy on smartphones. …”

Label data volume and label distribution. by Wenhao Ren (2561731)

“…These innovations significantly improve semantic segmentation accuracy while reducing computational overhead. …”

The structure of the context guided block. by Wenhao Ren (2561731)

“…These innovations significantly improve semantic segmentation accuracy while reducing computational overhead. …”

Wind-Driven Ignition Behavior of Wildland Fuels: Experimental Insights Under Controlled Conditions by Shusmita Saha (19162790)

“…Results show that higher wind speeds significantly increased ignition and peak temperatures while reducing ignition delay and transition times. …”

SEnet module. by Wenhao Ren (2561731)

“…These innovations significantly improve semantic segmentation accuracy while reducing computational overhead. …”

Image 5_Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities.jpeg by Zehra Edis (20561825)

“…<p>Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”

Data Sheet 1_Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities.pdf by Zehra Edis (20561825)

“…<p>Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”