Image 1_A comprehensive analysis of vitamin a deficiency burden and trends: insights from the global burden of disease study 2021 and future predictions to 2050.pdf by Qianhong Hu (22640267)

“…Background<p>Vitamin A deficiency (VAD) continues to pose a significant public health challenge, particularly in low socio-demographic index (SDI) regions, contributing to increased infections, blindness, and child mortality. …”

Supplementary file 1_Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling.pdf by Chun-Wei He (3909592)

“…We did not observe any change in baseline endocytosis; however, we did observe a significant decrease in recycling of GluA1-containing AMPARs in cultured hippocampal neurons from mice lacking SynDIG4. …”

Data_Sheet_1_The total joint arthroplasty care patterns in China during the COVID-19 pandemic: a multicenter cohort study.PDF by Tianyi Zhang (87298)

“…No significant changes were observed in the proportion of hospitalizations for TJA. …”

Data_Sheet_1_The efficacy and safety of isotonic and hypotonic fluids in intravenous maintenance fluid therapy in term newborns: national multicenter observational “neofluid” study... by Hasan Ozkan (6808268)

“…The primary outcomes were the change in mean plasma sodium (pNa) levels per hour (∆pNa mmol/L/h), the incidence of hyponatremia (pNa <135 mmol/L) and hypernatremia (pNa >145 mmol/L), and the occurrence of clinically significant changes in sodium levels (∆pNa >0.5 mmol/L/h).…”

Data_Sheet_1_The efficacy and safety of isotonic and hypotonic fluids in intravenous maintenance fluid therapy in term newborns: national multicenter observational “neofluid” study... by Hasan Ozkan (6808268)

“…The primary outcomes were the change in mean plasma sodium (pNa) levels per hour (∆pNa mmol/L/h), the incidence of hyponatremia (pNa <135 mmol/L) and hypernatremia (pNa >145 mmol/L), and the occurrence of clinically significant changes in sodium levels (∆pNa >0.5 mmol/L/h).…”

Data_Sheet_1_Dynamics of urban development patterns on thermal distributions and their implications on water spread areas of Vellore, Tamil Nadu, India.docx by D. R. Manjunath (19748899)

“…Moreover, spatial and time series analyses of WSAs indicated a significant increase in LST. Furthermore, a strong negative correlation was found between WSA and LST, with a 10% decrease in WSA potentially increasing LST by 0.12°C to 0.55°C in surrounding regions. …”

Data_Sheet_1_Dynamics of urban development patterns on thermal distributions and their implications on water spread areas of Vellore, Tamil Nadu, India.docx by D. R. Manjunath (19748899)

“…Moreover, spatial and time series analyses of WSAs indicated a significant increase in LST. Furthermore, a strong negative correlation was found between WSA and LST, with a 10% decrease in WSA potentially increasing LST by 0.12°C to 0.55°C in surrounding regions. …”

Image 1_The impact of Internet-based healthcare derived from the COVID-19 pandemic on outpatients in a cardiology department.tif by Jie Liu (15128)

“…</p>Results<p>Compared to the period before online services (T1), the second stage (T2) saw a significant decrease in total offline and general clinic visits. …”

Hemodynamic mechanisms underlying orthostatic hypotension in stroke survivors: a cross-sectional study by Kazuaki Oyake (7481357)

“…These individuals demonstrated significantly greater orthostatic cardiac index increases (F_(5,105) = 2.75, <i>p</i> = 0.023, partial η² = 0.126) and more pronounced orthostatic total peripheral resistance index decreases (F_(5,105) = 4.19, <i>p</i> = 0.002, partial η² = 0.166) than those without orthostatic hypotension.…”

Data Sheet 1_Metabolic adaptation fluctuates with different prediction equations: a secondary analysis based on a weight-loss clinical trial.docx by Molian Tang (18876955)

“…Both Katch-McArdle-determined RMR and BIA-determined RMR presented a significant decrease between baseline and the end of the intervention (week 16). …”

Table 3_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 4_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 6_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 2_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 5_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 1_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization by Xiaomin Wu (20328165)

“…Additionally, TAK-242 improved learning and memory impairments associated with HS and alleviated histopathological changes observed in the hippocampus. The treatment also resulted in a decrease in CD68-positive microglia and reduced expression levels of iNOS and TNF-α, while increasing CD206-positive cells and the expression of Arg-1 and IL-10. …”

Data Sheet 1_Differentiated response mechanisms of soil microbial communities to nitrogen deposition driven by tree species variations in subtropical planted forests.docx by Zheng Hou (67780)

“…</p>Results and discussion<p>The results showed that species differences led to variations in soil properties between the two forests, particularly a significant increase in soil pH in P. yunnanensis Franch. forests and a significant decrease in soil pH in P. armandii Franch. forests. …”

Table 3_Is takeout culture associated with rising colorectal cancer in young Chinese adults? An ecological analysis of GBD and CHNS data.xlsx by Ling Yao (16961)

“…Among non-neoplastic digestive diseases, inflammatory bowel disease showed the most pronounced decrease. In contrast, the burden of colorectal cancer has increased annually across all age groups. …”

Data Sheet 1_Is takeout culture associated with rising colorectal cancer in young Chinese adults? An ecological analysis of GBD and CHNS data.csv by Ling Yao (16961)

“…Among non-neoplastic digestive diseases, inflammatory bowel disease showed the most pronounced decrease. In contrast, the burden of colorectal cancer has increased annually across all age groups. …”