Image 7_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg حسب Yue Fu (64387)

"…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …"

Data Sheet 1_Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice.zip حسب Jiyao Zhao (10505867)

"…WB showed that P62 was significantly increased and RILP was significantly decreased in diabetic mice subjected to I/RI compared to healthy mice. …"

Image 1_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg حسب Yue Fu (64387)

"…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …"

Data Sheet 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.xlsx حسب Susan Carroll (17468)

"…Participants reported significant benefits from nature.</p>Discussion<p>Overall, the results showed that connecting with nature significantly contributes to flourishing in highly sensitive individuals, particularly in middle to older age. …"

Image 1_Depression score and body mass index mediate the association between dietary vitamin C intake and female infertility: a study based on NHANES 2013–2018.tif حسب Lingxin Zheng (14554387)

"…A threshold non-linear association between VC and infertility was more significant in women aged from 18 to 34 (P = 0.033). …"

Data Sheet 1_Association of dietary index for gut microbiota and cardiovascular diseases in American adults: evidence from National Health and Nutrition Examination Survey 1999–201... حسب Hong Luo (205745)

"…Background<p>As a significant health burden, cardiovascular disease (CVD) contributes substantially to global disease and death rates. …"

Data Sheet 3_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... حسب Zhe Sun (328682)

"…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …"

Data Sheet 4_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... حسب Zhe Sun (328682)

"…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …"

Image 4_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg حسب Yue Fu (64387)

"…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …"

Table 1_Effects of irrigation and fertilization management on kiwifruit yield, water use efficiency and quality in China: A meta-analysis.xls حسب Yuehua Ding (22434916)

"…However existing kiwifruit water-saving and fertilizer-reduction studies showed significant contradictions in the results of water and fertilizer management. …"

Data Sheet 5_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... حسب Zhe Sun (328682)

"…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …"

Table 3_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx حسب M. Virginia Martín (6321047)

"…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …"

Supplementary file 1_Altered microstate C and D dynamics in high social anxiety: a resting-state EEG study.docx حسب Huoyin Zhang (21265508)

"…</p>Results<p>The high social anxiety group exhibited significantly increased duration and coverage of microstate C (associated with processing personally significant information and self-reflection) and decreased duration and coverage of microstate D (associated with executive functioning). …"

Table 7_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx حسب M. Virginia Martín (6321047)

"…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …"

Supplemental Figures حسب Danielle A. Jeffrey (21187329)

"…FXR1 has seven isoforms, including isoforms mostly expressed in skeletal and cardiac tissue, and play a significant role in heart development and function. …"

Image 2_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg حسب Yue Fu (64387)

"…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …"

Image 6_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg حسب Yue Fu (64387)

"…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …"

Octβ2R and cAMP underlie the Brp compartmental heterogeneity. حسب Hongyang Wu (8856740)

"…*<i>P</i> < 0.05; ns = not significant. <b>(B)</b> Knockdown of Rut significantly decreased the Brp heterogeneity level in γ KCs. …"

Table 1_Esmolol improves sepsis outcomes through cardiovascular and immune modulation.docx حسب Da Jing (404219)

"…Background<p>Sepsis poses significant mortality risks. Esmolol, a β1-adrenergic blocker, may improve outcomes through cardiovascular and immune modulation. …"

Forest Plots, SROC Curve, and Diagnostic Performance Analyses of ctDNA Biomarkers for Early Pancreatic Cancer Detection. حسب Zeyi Zheng (16879938)

"…E: Deeks’ funnel plot asymmetry test for publication bias assessment. A non-significant p-value (p > 0.05) suggests no evidence of significant publication bias. …"