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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
changes decrease » largest decrease (Expand Search), change increases (Expand Search)
larger decrease » marked decrease (Expand Search)
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20161
Image 2_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif
Published 2025“…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”
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20162
Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents
Published 2024“…Further mechanistic studies revealed that compound <b>13</b> significantly induced cell apoptosis by increasing the expression levels of cleaved caspase-3 and reducing Bcl-2 proteins through downregulating the EGFR/PI3K/Akt signalling pathway, leading to the inhibition of proliferation in HCT116 and PC9 cells. …”
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20163
mAP0.5 Curves of various models.
Published 2025“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”
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20164
Supplementary Material for: A common variant in NID1 gene associated with the prognosis of heart failure
Published 2025“…Western blot analysis demonstrated that the protein level of NID1 was significantly higher in the rs3738530-T allele compared to the A allele (P < 0.05). …”
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20165
Data Sheet 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.pdf
Published 2024“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”
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20166
Data Sheet 12_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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20167
Image 14_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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20168
Dust particle flow trace diagram.
Published 2025“…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …”
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20169
Adverse events in patients with castration-resistant prostate cancer treated with ra-223: a retrospective pharmacovigilance study
Published 2024“…Four sequential analysis strategies were employed to assess the significance of these AEs.</p> <p>In total, 4,228 Ra-223-related AE reports were identified in the FAERS database. …”
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20170
Table 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin...
Published 2025“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”
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20171
Model inputs.
Published 2024“…Clinical findings have showed that deprescribing service significantly decreased inappropriate PPIs utilization. …”
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20172
Vitreous Olink Proteomics Uncovers Novel Inflammatory Proteins in Patients with Proliferative Diabetic Retinopathy
Published 2025“…Functional studies demonstrated that the conditioned medium from HG-exposed MG significantly enhanced endothelial cell proliferation, migration, and tube formation. …”
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20173
Image 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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20174
Discrete phase parameter setting.
Published 2025“…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …”
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20175
Data Sheet 3_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.csv
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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20176
Comparative diagrams of different indicators.
Published 2025“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”
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20177
Table 1_Case report: Treatment of severe phorate poisoning.xlsx
Published 2025“…In the follow-up treatment, the concentration of five metabolites gradually decreased. The concentration of the phorate sulfoxide and phorate sulfone rebounded with the suspension of HP, but that of the other metabolites did not rebound. …”
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20178
Bgh/GelMA/CMCS hydrogel with bone MSC-EVs for lunate defect repair
Published 2025“…In vivo, the M1/M2 ratio and inflammatory factors decreased significantly one-week post-implantation, while CD31 and VEGF-positive cells increased at four weeks, and BMP2 and OPN-positive cells at eight weeks. …”
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20179
Supplementary file 1_Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.docx
Published 2025“…Lipid metabolism was significantly altered in moderate-altitude athletes, including pathways such as linolenic and linoleic acid, sphingolipid, and arachidonic acid, as well as processes involving the transfer of acetyl groups into mitochondria and fatty acid biosynthesis. …”
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20180
Table 1_Study on the effect of different types of sugar on proliferation and inflammatory in goose fatty liver.docx
Published 2025“…Glucose combined with si-CPT1A treatment decreased CyclinD3 while increasing p21 expression. …”