Table1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.docx by Zi Yang (276531)

“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

This is raw data of IL-10 ELISA. by Farzad Nasri (8941850)

“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”

Supplementary file 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burd... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”

This is raw data of NF-κB real-time PCR. by Farzad Nasri (8941850)

“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”

Table 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”

Image3_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Image4_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

This is raw data of IL-1β real-time PCR. by Farzad Nasri (8941850)

“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”

This is raw data of β-catenin real-time PCR. by Farzad Nasri (8941850)

“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”

Table 2_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”

Image2_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Details of the primers applied in real-time PCR. by Farzad Nasri (8941850)

“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”

This is raw data of viability data. by Farzad Nasri (8941850)

“…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”

Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip by Alessia Cavallo (13036581)

“…Th1/Th17 cytokines significantly inhibited the high calcium-induced synthesis of phospholipids (PCs, PEs, SMs), and short-chain ceramides, while the synthesis of ceramides with medium to long carbon chains was upregulated. …”

Data Sheet 1_Ningxiang pigderived Enterococcus hirae regulates the inflammatory function and enhances the protection of piglets against ETEC challenge.docx by Longlin Zhang (9956945)

“…Additionally, ETEC infection significantly increased the spleen index and the expression of inflammatory cytokines in the spleen, serum and intestine, with decreasing serum sIgA and colonic SCFAs of piglets. …”

Effect of SBS on rumen fermentation (n = 5). by Minghui Zhang (298745)

“…The results showed that: (1) Compared with the CON group, the dressing percentage and eye muscle area in the SBS24 group significantly increased (<i>P</i> < 0.05); (2) Compared with the CON group, the butyrate content and total fatty acid content inthe SBS24 group significantly increased (<i>P</i> < 0.05); (3) Compared with the CON group, the Simpson index of the SBS groups significantly increased (<i>P</i> < 0.05), while the Shannon index of the SBS12, SBS18, and SBS24 groups significantly decreased (<i>P</i> < 0.01). …”

Classification of bioactive substances in SBS. by Minghui Zhang (298745)

“…The results showed that: (1) Compared with the CON group, the dressing percentage and eye muscle area in the SBS24 group significantly increased (<i>P</i> < 0.05); (2) Compared with the CON group, the butyrate content and total fatty acid content inthe SBS24 group significantly increased (<i>P</i> < 0.05); (3) Compared with the CON group, the Simpson index of the SBS groups significantly increased (<i>P</i> < 0.05), while the Shannon index of the SBS12, SBS18, and SBS24 groups significantly decreased (<i>P</i> < 0.01). …”

OTU venn diagram. by Minghui Zhang (298745)

“…The results showed that: (1) Compared with the CON group, the dressing percentage and eye muscle area in the SBS24 group significantly increased (<i>P</i> < 0.05); (2) Compared with the CON group, the butyrate content and total fatty acid content inthe SBS24 group significantly increased (<i>P</i> < 0.05); (3) Compared with the CON group, the Simpson index of the SBS groups significantly increased (<i>P</i> < 0.05), while the Shannon index of the SBS12, SBS18, and SBS24 groups significantly decreased (<i>P</i> < 0.01). …”

PCR reaction system. by Minghui Zhang (298745)

“…The results showed that: (1) Compared with the CON group, the dressing percentage and eye muscle area in the SBS24 group significantly increased (<i>P</i> < 0.05); (2) Compared with the CON group, the butyrate content and total fatty acid content inthe SBS24 group significantly increased (<i>P</i> < 0.05); (3) Compared with the CON group, the Simpson index of the SBS groups significantly increased (<i>P</i> < 0.05), while the Shannon index of the SBS12, SBS18, and SBS24 groups significantly decreased (<i>P</i> < 0.01). …”

Nutritional composition of SBS (DM basis, %). by Minghui Zhang (298745)

“…The results showed that: (1) Compared with the CON group, the dressing percentage and eye muscle area in the SBS24 group significantly increased (<i>P</i> < 0.05); (2) Compared with the CON group, the butyrate content and total fatty acid content inthe SBS24 group significantly increased (<i>P</i> < 0.05); (3) Compared with the CON group, the Simpson index of the SBS groups significantly increased (<i>P</i> < 0.05), while the Shannon index of the SBS12, SBS18, and SBS24 groups significantly decreased (<i>P</i> < 0.01). …”