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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
changes decrease » larger decrease (Expand Search), change increases (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
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17821
Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure
Published 2024“…Three piRNAs (mmpiR-1500602, mmpiR-0201406, and mmpiR-0200026) were significant after multiple testing correction (all downregulated in the male Pb-exposed brain in comparison to control; FDR < 0.05). …”
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17822
Table 1_Coptis japonica Makino ethanol extracts attenuates cancer cachexia induced muscle and fat wasting through inhibition of the STAT3 signaling pathway.docx
Published 2025“…Our results demonstrated that CJME significantly decreased the mRNA and protein levels of muscle-specific E3 ubiquitin ligases Atrogin-1 and MuRF1 in myotubes exposed to CT26 CM. …”
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17823
Data Sheet 2_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.xlsx
Published 2024“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”
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17824
Supplementary Material for: Acute interstitial nephritis associated to Pertussis infection: a case report and review of the literature
Published 2025“…Initial laboratory findings revealed mild leukocytosis and significantly elevated serum creatinine (5.17 mg/dL), with urinalysis showing leukocyturia and proteinuria. …”
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17825
Data Sheet 2_Pandan–vanilla rotation mitigates Fusarium wilt disease in vanilla: insights from rhizosphere microbial community shifts.xlsx
Published 2025“…Crop rotation significantly increased fungal diversity and richness. …”
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17826
Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction
Published 2025“…Given that mitochondria are the primary source of reactive oxygen species (ROS), we assessed cellular ROS and mitochondrial superoxide levels by flow cytometry and found a significant increase. GOT1 knockdown increased the sensitivity of cells to cisplatin and decreased the volume of tumors in vivo. …”
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17827
Sex-specific responses of mosquitoes to <i>Bti</i> pesticide and odonate predators
Published 2025“…We found that Bti reduced larval abundance by ~90% within 48 hours but did not induce an overcompensatory response in adult production or fitness. Predators had no significant effect on larvae within 48 hours, but they did have sex-specific effects on the abundance and size of adult mosquitoes. …”
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17828
Table 3_Comparison between the protective effect of the orally administered atorvastatin and safflower (Carthamus tinctorius) in hypercholesterolemic male rats.docx
Published 2025“…The induced hypercholesterolemia significantly raised liver function enzymes, lipid peroxidation (14.9 ± 0.11 mg/dL), total cholesterol (273.3 ± 1.1 mg/dL), triglycerides (223.0 ± 4.1 mg/dL), low-density lipoproteins (204.7 ± 0.9 mg/dL), very low-density lipoproteins (44.6 ± 0.8 mg/dL), troponin, creatine kinase (CK), and adrenaline while decreased antioxidant enzymes, high-density lipoprotein (HDL), and vitamin D (11.1 ± 0.5 ng/mL). …”
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17829
Image 1_Tetramethylpyrazine and renal ischemia-reperfusion injury: a systematic review and meta-analysis of preclinical studies.pdf
Published 2025“…</p>Results<p>Thirty studies involving 559 animals were identified for analysis. TMP treatment significantly decreased Scr (SMD = 2.35, 95% CI: −2.97 to −1.72, P < 0.05), BUN (SMD = −2.4, 95% CI: −3.01 to −1.79, P < 0.05). …”
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17830
Video 1_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4
Published 2024“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”
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17831
Image 2_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.tif
Published 2024“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”
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17832
Characteristics comparison of related literature.
Published 2025“…<div><p>Capturing congestion propagation among different facilities at intersections in dynamic stochastic traffic environments poses significant challenges, particularly under oversaturated conditions. …”
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17833
Table 1_Physical and chemical characteristics of pyrogenic carbon from peatland vegetation fires differ across burn severities.xlsx
Published 2025“…O/C and H/C ratios decreased with increasing severity. FTIR showed that distinct spectra were produced between severity groups, reflecting increased sample aromaticity with burn severity.…”
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17834
Data Sheet 9_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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17835
Supplementary file 1_A cross-sectional study of the current status of psychological health and its correlation with academic performance in medical students: taking medical student...
Published 2025“…</p>Conclusion<p>The undergraduates face significant challenges in depression, anxiety, insomnia, and perceived stress, and these have negative effects on their academic performances; in particular, the depressive symptoms and perceived stress can significantly reduce their academic performances. …”
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17836
Table 1_Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.doc
Published 2025“…No significant differences were observed in other indicators.…”
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17837
Data Sheet 1_Probiotic administration correlated with reduced diarrheal incidence and improved gut microbiota diversity in young goats.pdf
Published 2025“…The predominant phyla identified were Pseudomonadota, Bacteroidetes, and Bacillota.Increased levels of Xylanibacter, UCG-055, Bacteroides, and Escherichia-Shigella were noted in healthy treated kids, while Prevotellaceae UG_001 and Proteus decreased.</p>Discussion<p>The findings highlight significant gut microbiota differences between healthy and diarrheal kids, suggesting that modifications in gut microbiota composition could alleviate diarrhea, contributing to preventive and therapeutic strategies for this condition.…”
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17838
Table 1_Biliary microbiota in disease-free, obstructive and post-drainage biliary tracts.docx
Published 2025“…Furthermore, the increased incidence of bacterial infections following biliary drainage poses a significant clinical concern; however, the relationship between biliary drainage and biliary flora remains poorly understood. …”
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17839
Data Sheet 6_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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17840
Table 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx
Published 2025“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”