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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
changes decrease » larger decrease (Expand Search), change increases (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
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18141
CircFNDC3B inhibits vascular smooth muscle cells proliferation in abdominal aortic aneurysms by targeting the miR-1270/PDCD10 axis
Published 2024“…</i> Our findings revealed a significant upregulation of circFNDC3B expression in AAA clinical specimens compared to normal tissues. …”
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18142
Table 1_Eculizumab for the acute attack of neuromyelitis optica spectrum disorder.docx
Published 2025“…Following eculizumab, six of the seven ON patients showed significant improvements in visual acuity and visual fields, with five recovering to near-normal or pre-attack vision. …”
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18143
Data Sheet 1_Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and...
Published 2025“…IBC-treated astrocytes exhibited significant clearance of extracellular amyloid beta. …”
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18144
Data Sheet 1_Role of intercellular interactions on single cell and population level responses: considerations for multicellular bioreporter design.docx
Published 2025“…</p>Results<p>Simulations for 20 s of simulated time show that while final reporter protein count per cell decreased as cell count increased, aggregate final reporter protein number across all cells significantly increased. …”
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18145
DataSheet1_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.docx
Published 2024“…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …”
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18146
Data Sheet 1_Application of chlorous acid water for disinfection of surgical site in dairy cows.pdf
Published 2025“…The cleansing procedure significantly reduced the SPCB, EF, and SP on the skin after clipping, and all disinfection methods significantly decreased the SP after cleansing. …”
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18147
Data Sheet 1_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx
Published 2025“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”
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18148
Data Sheet 1_Distalization of the mandibular first molar with clear aligners: a 3D finite element study.docx
Published 2025“…For the second molar, the most significant mesial displacement was observed in the second molar ATT group.…”
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18149
Raman spectra (a) GNPs, and (b) Ag nanoparticles.
Published 2025“…Higher nanoparticle loadings improved conductivity further but caused significant viscosity increases and reduced stability. …”
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18150
Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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18151
Neural lamella remodeling is needed for macrophage invasion.
Published 2025“…(<b>C</b>) Panglial expression of <i>Pvf2</i> and concomitant knockdown of <i>STAT92E</i> decreases the number of invaded macrophages by ~ 10-fold. …”
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18152
Data Sheet 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.pdf
Published 2025“…</p>Results<p>By week 24, secukinumab treatment led to significant reductions in disease severity scores (QMG: 60.7%; MG-QOL15: 58.3%; MG-ADL: 64.1%) and AChR antibody levels (69.23%). …”
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18153
Data Sheet 1_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind...
Published 2025“…Additionally, HLTP reversed 63 CUMS-induced abnormal serum metabolites, primarily affecting tryptophan metabolism, niacin and nicotinamide metabolism, and porphyrin metabolism. Significant correlations were observed among gut microbial composition, serum metabolite levels, biochemical indices, and behavioral outcomes.…”
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18154
Data Sheet 1_Investigating the influence of a thin copper film coated on nickel plates through physical vapor deposition for electrocatalytic nitrate reduction.docx
Published 2025“…NO<sub>3</sub><sup>−</sup> was primarily reduced to NH<sub>4</sub><sup>+</sup>, with no significant difference in the NO<sub>3</sub><sup>−</sup> conversion rate observed as a function of the Cu thickness. …”
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18155
Table1_Predicting candidate miRNAs for targeting begomovirus to induce sequence-specific gene silencing in chilli plants.docx
Published 2024“…Chilli cultivars infected with begomovirus have suffered significant decreases in biomass output, negatively impacting their economic characteristics. …”
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18156
Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx
Published 2025“…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …”
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18157
Data Sheet 1_Enhancing tuber yield and nutraceutical quality of potato by supplementing sunlight with LED red-blue light.pdf
Published 2025“…‘Colomba’ prioritized the accumulation of free amino acids, GABA, and polyphenols, enhancing the plant stress response and antioxidant capacity, and adapted well to variable light conditions, with significant increases in tuber yield under LED treatments. …”
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18158
Image 2_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”
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18159
Image 2_Ticagrelor vs. clopidogrel in dual antiplatelet therapy after coronary artery bypass surgery: a meta-analysis.tif
Published 2025“…No statistically significant difference was found in the rates of major bleeding (OR = 1.16; 95% CI 0.69–1.96; p = 0.57; p heterogeneity = 0.26; I<sup>2</sup> = 23%) between two groups. …”
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18160
Data Sheet 1_Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3.docx
Published 2025“…Mechanistically, anti-STAT3 mcDNA induces apoptosis and necrosis in treated cells, also revealing a certain dose-dependency, while also decreasing cell proliferation. Finally, our inhibitor significantly downregulates STAT3-dependent anti-apoptotic genes MCL1 and PIM1.…”