Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

“…Objective<p>The phase III ASTRUM-007 trial demonstrated significant clinical benefit in patients with PD-L1-positive esophageal squamous cell carcinoma (ESCC) treated with first-line serplulimab plus chemotherapy. …”

Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx by Naama Lax (20998004)

“…TMA event-free status was reached in 15 (63%) patients. Significant improvements were observed in platelet count (63%), lactate dehydrogenase levels (76% within the first week), hemoglobin (60%), and estimated glomerular filtration rate (79%); while CH-50 levels decreased. …”

Table 1_The effect of khat chewing on sexual desire among adults in North East Ethiopia: a propensity score-match analysis.docx by Temesgen Gebeyehu Wondmeneh (9716120)

“…Background<p>Although the number of khat chewers has increased from time to time in Ethiopia, the direction (increased or decreased) of khat chewing on sexual desire is not well known due to the absence of adequate studies. …”

Image10_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellul... by Huipeng Fang (12587509)

“…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”

Table 1_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.xlsx by Jia-Yi Wang (490704)

“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”

Table 2_Survival assessment in extremely preterm neonates in a middle-income setting.docx by Maria J. Rodriguez-Sibaja (17456689)

“…Notably, survival after extremely preterm birth was associated with significant morbidity.</p>…”

Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX by Shaoqun Huang (19810725)

“…</p>Conclusion<p>Our study explored a significant correlation between PHDI and biological aging, indicating that adherence to PHD may prevent biological aging.…”

Data - <i>trus</i>RNAi wing size measurement. by Saeko Takada (21616085)

“…In mutant larvae, we found decreased cell proliferation and growth defects in the brain and imaginal discs. …”

Image5_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4⁺ and CD8⁺ T cells in implanted limb muscles of mouse models. …”

Characteristics of children in the study. by Shijie Yu (511369)

“…</p><p>Conclusions:</p><p>This study found a significant association between myopia and worse HRQOL in primary and secondary school children. …”

Image6_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4⁺ and CD8⁺ T cells in implanted limb muscles of mouse models. …”

ORS and zinc coverage, by country, DHS data only. by Keith Beam (20700854)

“…Our findings demonstrate the long-term success of the SUZY project and provide insights into best practices for impactful zinc scale-up programs including significant pre-launch implementation research addressing key knowledge gaps and partnering with research organizations. …”

Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf by Junjie Jiang (7255706)

“…</p>Results<p>Analysis of data from the 2007–2018 NHANES survey revealed a significant negative association between CDAI and sleep disorders (OR = 0.854, 95% CI 0.821–0.888, P < 0.001). …”

Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i> by Meng-Ru Guo (21375491)

“…Research has shown that the absence of Cdc4, an F-box protein in <i>C. neoformans</i>, decreases virulence, yet the mechanisms by which Cdc4 affects these processes remain unclear. …”

Image 1_Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database.png by Yu Liu (6938)

“…Notable PTs included *petechiae* (ROR 9.87), *hemiparesis* (ROR 9.36), and *platelet count decreased* (ROR 8.61). Unexpected AEs, such as *pulmonary embolism* (ROR 4.96) and *Pneumocystis jirovecii pneumonia* (ROR 7.09), were identified. …”

Research framework. by Wanzhuang Huang (17357306)

“…The results indicated that from 1990 to 2020, the area of unused land in the Shiyang River Basin decreased the most, mainly converted into farmland, construction land, and water areas. …”

Genomic DNA yield and integrity obtained from MDR-TB and DS-TB isolate cultures. by Linzy Elton (9750221)

“…A) DNA yields extracted from MGIT tubes over time; there was no change in MDR-TB DNA yield, but the DS-TB isolate yield decreased. …”

Post-traumatic stress disorder in German youth: representative claims data pre- vs. intra-COVID-19-pandemic by Jule Leickert (21598275)

“…Hospitalisations among female adolescents only decreased for those with low SES (OR = 0.67 [0.38, 1.19]).…”

Data Sheet 1_Analysis of pharmacotherapeutic approaches for multiple myeloma and correlated renal and pulmonary impairments: a retrospective real-world registry study in the Greate... by Ayman Alhejazi (21092054)

“…Background<p>Multiple myeloma (MM) is a plasma cell malignancy with significant unmet medical needs, particularly in the treatment of relapsed and refractory disease. …”

Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario by Karoliny Nune Santos (21752603)

“…<p>Preeclampsia (PE) is characterized by systemic endothelial dysfunction and remains a significant clinical challenge. Activation of NLRP3 inflammasome, reactive oxygen species (ROS) production, and pyroptosis and autophagy are important mechanisms in this condition. …”