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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
linear decrease » linear increase (Expand Search)
clinical areas » critical areas (Expand Search), clinical care (Expand Search), clinical cases (Expand Search)
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20941
Image 7_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.pdf
Published 2025“…We recruited 114 individuals in the PWH group and 58 individuals in the HC group, from whom fecal samples were collected for 16S rRNA gene sequencing of the V3–V4 region. Significant differences in α diversity and β diversity (p-values < 0.05) were observed between the two groups. …”
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20942
Supplementary file 1_Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut micro...
Published 2025“…</p>Results<p>HSYA significantly inhibited HFD-induced weight gain and alleviated liver inflammation. …”
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20943
Data Sheet 3_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf
Published 2025“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”
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20944
Data Sheet 2_Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy.zip
Published 2025“…The immune infiltration analysis showed that there was a significantly increased abundance of macrophages and a decreased abundance of CD4 and CD8 T cells, including Tr1, nTreg, Tfh, CD8 naïve, cytotoxic T cells and effector memory T cells in the epilepsy group. …”
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20945
Table_1_RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance.DOCX
Published 2025“…The hearts were subjected to LC-MS/MS based lipid mediator profiling. Many SPMs were significantly reduced in septic hearts, among which RvE1 had a ~93-fold reduction. …”
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20946
Temporal change in average visitor vitality.
Published 2024“…The factors within the Park attributes (G1) and the park’s social media level (G4) showed a two-way interaction strength increase. (4)The coefficients of influence of impact factors on the space heterogeneity of vacation park vitality exhibit significant variation. The positive indicators have a spatial distribution that decreases from the northwest to the southeast, with the old city district having higher coefficients than the new city district. …”
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20947
Data Sheet 1_Disease spectrum of patients with hospital-acquired multidrug-resistant organism infections in the intensive care unit: a retrospective study.doc
Published 2025“…</p>Conclusion<p>Our data show the mortality rate of hospital-acquired MDRO infections decreased during COVID-19 and increased after restrictions eased. …”
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20948
Supplementary Material for: Adverse Prognosis in Membranous Nephropathy with PLA2R1 Epitope Spreading: A Prospective Study
Published 2025“…In a univariate analysis, multi-domain recognition decreases the probability of remission[HR, 0.38 (95% CI, 0.16-0.87), P = 0.022]. …”
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20949
Table2_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease...
Published 2024“…Despite global declines in IHD incidence over the last three decades, decreasing trends in incidence have slowed and, in some countries, flattened. …”
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20950
DataSheet1_Efficacy and safety of danshen class injections in the treatment of coronary heart disease: a network meta-analysis.docx
Published 2024“…The results of NMA showed that, XD injection significantly enhances clinical efficacy; STS is more effective in reducing hs-CRP levels; DSDFSY shows better efficacy in decreasing IL-1 and increasing NO levels; DSCXQ has a greater advantage in reducing IL-6 levels; GXN is more effective in regulating SOD levels; and DH is better at reducing MDA levels.…”
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20951
The relationship between early-onset preeclampsia and the prognostic nutritional index and inflammatory markers
Published 2024“…The prognostic nutritional index (PNI) was significantly lower in the early-onset preeclampsia group than in the normotensive group (p < 0,001). …”
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20952
Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”
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20953
Data Sheet 1_Microbiota profiling from biopsied tissues in complex infections: a diagnostic and prognostic analysis through metagenomic next-generation sequencing.docx
Published 2025“…Early mNGS sampling within 7 days after admission was associated with a significantly decreased risk of all-cause mortality (HR 0.18, 95% CI 0.04–0.94; P=0.04), treatment failure (OR 0.17, 95% CI 0.05–0.66; P=0.01), and increased probability of clinical resolution (OR 3.03, 95% CI 1.24–7.40; P=0.01).…”
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20954
Table 1_Study on Chaiyuwendan decoction’s inhibition of hippocampal neuron apoptosis to alleviating depression by activating the AKT/CREB pathway.docx
Published 2025“…Chaiyuwendan decoction (CYWD) has significant clinical efficacy in treating depression, however, its specific mechanism is still unclear. …”
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20955
Performance following comparative feedback
Published 2025“…The findings indicate that mixed comparative feedback is associated with decreased subsequent performance, whereas consistently negative feedback can be beneficial. …”
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20956
Table 2_Effect of midwife-led continuity of care combined with individualized breast management on postpartum recovery and lactation function in women undergoing cesarean section.d...
Published 2025“…Although the incidence of pelvic floor dysfunction showed a decreasing trend in the intervention group, this difference was not statistically significant (p > 0.05). …”
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20957
Image1_Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway induction.tif
Published 2024“…The incidence is expected to increase as the average life expectancy increases, highlighting asthma as a significant health challenge in an aging society. The etiology of asthma is linked to an imbalance of Th1 and Th2 cells, respiratory inflammation, and pulmonary cell proliferation. …”
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20958
DataSheet1_Association between various insulin resistance indices and cardiovascular disease in middle-aged and elderly individuals: evidence from two prospectives nationwide cohor...
Published 2024“…Multivariate logistic regression analysis indicated that a decreasing eGDR significantly increased the incidence of CVD both presently and in the future. …”
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20959
Video 5_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”
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20960
Data Sheet 1_The role of ATP6V0D2 in breast cancer: associations with prognosis, immune characteristics, and TNBC progression.docx
Published 2024“…Objective<p>Researches have identified ATPase H+ transporting V0 subunit d2 (ATP6V0D2) as a significant factor in various cancers. However, its prognostic value in breast cancer (BRCA) and its biological role in BRCA cells remain unclear.…”