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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
linear decrease » linear increase (Expand Search)
clinical areas » critical areas (Expand Search), clinical care (Expand Search), clinical cases (Expand Search)
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18781
Table 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.docx
Published 2025“…Clinicopathologic characteristics were significantly correlated with risk scores. There were significant differences in the proportion of tumor-infiltrating immune cells, the TP53 mutation rate, the expression of immune checkpoint-related genes, and IC50 of the chemotherapeutic drugs between the low- and high-risk groups. …”
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18782
Identification of a Novel Virulence Factor in <i>Klebsiella pneumoniae</i> through CpxR-Dependent Transcriptional Activation
Published 2025“…Among the genes exhibiting significantly decreased expression upon <i>cpxR</i> deletion<i>, </i>we identified a novel potential virulence factor KPHS_28080. …”
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18783
Table_4_Combinatorial protection of cochlear hair cells: not too little but not too much.docx
Published 2024“…All compounds were added at a dosage below that required for significant protection in the assay, and only this single dose was then employed. …”
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18784
Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx
Published 2025“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”
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18785
Table 1_The real-world safety of Nivolumab: a pharmacovigilance analysis based on the FDA adverse event reporting system.docx
Published 2025“…The most frequently reported AEs included fatigue, dyspnea, musculoskeletal pain, decreased appetite, cough, nausea, and constipation. …”
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18786
Table 3_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
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18787
Table 1_Mediation effects of metabolites and sex hormones on the relationship between body mass index and breast cancer: Mendelian randomization analysis and mediation analysis.xls
Published 2024“…</p>Results<p>The IVW model indicated significant negative causal correlations between BMI and BC, ER<sup>+</sup>BC, and ER<sup>-</sup>BC. …”
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18788
Image 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif
Published 2025“…Clinicopathologic characteristics were significantly correlated with risk scores. There were significant differences in the proportion of tumor-infiltrating immune cells, the TP53 mutation rate, the expression of immune checkpoint-related genes, and IC50 of the chemotherapeutic drugs between the low- and high-risk groups. …”
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18789
Image 3_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disease St...
Published 2025“…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…”
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18790
Image 3_Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024.jpeg
Published 2025“…The reported incidence of syphilis decreased by an average of −3.53% per year across all age groups (95% CI: −4.34, −2.70%). …”
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18791
Table 1_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.docx
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
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18792
Table 5_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
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18793
Image 1_Temporal trends of community and climate changes in the anthropocene: 21-year dynamics of four major functional groups in a rocky intertidal habitat along the Pacific coast...
Published 2025“…We aimed to examine the 21-year trends in regional abundance at both functional-group and species levels, plus their driving mechanisms and their dependence on species properties (thermal niche, calcification status, and vertical niche). Significant temporal trends in abundance were detected at functional-group levels for benthic algae (increasing) and herbivores and carnivores (both decreasing); they followed the temporal population trends of the dominant species. …”
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18794
Table 1_Effect of Ebenatide on glycemic metabolism and body fat in patients with type 2 diabetes mellitus.docx
Published 2025“…The triglyceride-glucose index (TyG) decreased at Week 52 compared with baseline (P<0.01). …”
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18795
Fig 3 -
Published 2024“…</b> Mutant <i>hsp-90</i> significantly decreases the levels of total and phosphorylated species of TDP-43 (pTDP-43). …”
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18796
Data Sheet 4_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf
Published 2025“…Metabolite analysis revealed associations between decreased proline, isoleucine, valine, and alanine levels with IS. …”
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18797
Data Sheet 1_The Sdp-SH3b2 domain contained in Lactobacillus johnsonii N6.2-derived extracellular vesicles inhibit murine norovirus replication.pdf
Published 2024“…We found that RAW 264.7 Macrophages treated with EVs significantly decreased the levels of MNV-1 genome. These results were consistent with an increase in expression of Oas1b, Oas2, Oasl, Mx1, Mx2 and Ifi44l (6 hours post infection). …”
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18798
Data Sheet 1_Synergistic amelioration of renal oxidative stress, inflammation, and fibrosis by combination of metformin and Clinacanthus nutans leave extracts in a type 2 diabetic...
Published 2025“…Additionally, DMCOM significantly decreased malondialdehyde levels. Notably, diabetic rats treated with DMCOM exhibited a significant reduction in parameters associated with renal dysfunction, as evidenced by decreased inflammation markers, along with downregulated fibrotic markers.…”
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18799
Image 2_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disease St...
Published 2025“…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…”
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18800
Presentation 1_Granola consumption with multiple prebiotics in Japanese participants increases Bifidobacterium abundance and improves stress and subjective sleepiness.pptx
Published 2025“…</p>Results<p>After 8 weeks, subjective insomnia scores and sleep onset and maintenance improved significantly, whereas the stress and mood disturbance scores decreased significantly. …”