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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
linear decrease » linear increase (Expand Search)
clinical case » clinical cases (Expand Search), clinical care (Expand Search), clinical course (Expand Search)
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18961
Table 2_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx
Published 2025“…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …”
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18962
Table 1_Global, regional, and national burden of liver cancer in adolescents and young adults from 1990 to 2021: an analysis of the global burden of disease study 2021 and forecast...
Published 2025“…East Asia bears the highest burden, with males experiencing significantly higher rates than females. The burden increases with age, peaking at 35–39 years. …”
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18963
Image 7_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg
Published 2025“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”
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18964
Data Sheet 1_Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice.zip
Published 2025“…WB showed that P62 was significantly increased and RILP was significantly decreased in diabetic mice subjected to I/RI compared to healthy mice. …”
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18965
Data Sheet 2_Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas.pdf
Published 2025“…Attention scores also decreased at 800 meters (94.4%, p = 0.002). No significant changes were found in parietal, temporal, or occipital lobe functions. …”
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18966
Image 1_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg
Published 2025“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”
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18967
Table 1_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.docx
Published 2025“…C-terminal telopeptide (CTX) showed a small, statistically significant reduction (MD −0.09, 95% CI −0.14 to −0.05) with uncertain clinical relevance. …”
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18968
DataSheet1_Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease.zip
Published 2024“…The significant changes that occurred in both the liver and lung were more pronounced in the liver.…”
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18969
DataSheet2_Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease.zip
Published 2024“…The significant changes that occurred in both the liver and lung were more pronounced in the liver.…”
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18970
Data Sheet 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.xlsx
Published 2025“…Participants reported significant benefits from nature.</p>Discussion<p>Overall, the results showed that connecting with nature significantly contributes to flourishing in highly sensitive individuals, particularly in middle to older age. …”
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18971
Data Sheet 2_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip
Published 2025“…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …”
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18972
Data Sheet 3_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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18973
Data Sheet 4_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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18974
Image 4_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg
Published 2025“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”
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18975
Table 1_Effects of irrigation and fertilization management on kiwifruit yield, water use efficiency and quality in China: A meta-analysis.xls
Published 2025“…However existing kiwifruit water-saving and fertilizer-reduction studies showed significant contradictions in the results of water and fertilizer management. …”
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18976
Data Sheet 5_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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18977
Data Sheet 2_Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block.doc
Published 2025“…The hemodynamic indicators showed a slight reduction in intraoperative blood pressure and decreased numerical rating scale scores on the first postoperative day without significant differences in other indicators.…”
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18978
Table 3_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx
Published 2025“…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …”
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18979
Supplementary file 1_Altered microstate C and D dynamics in high social anxiety: a resting-state EEG study.docx
Published 2025“…</p>Results<p>The high social anxiety group exhibited significantly increased duration and coverage of microstate C (associated with processing personally significant information and self-reflection) and decreased duration and coverage of microstate D (associated with executive functioning). …”
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18980
Supplementary file 4_Practical utility of meropenem therapeutic drug monitoring: a systematic review of evidence for clinical application.docx
Published 2025“…CRP levels decreased significantly (mean difference = 14.91; 95% CI: 2.79–27.02), while changes in PCT, WBC, and neutrophil ratios were non-significant. …”