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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
clinical decrease » clinical disease (Expand Search), linear decrease (Expand Search), clinical areas (Expand Search)
clinical case » clinical cases (Expand Search), clinical care (Expand Search), clinical course (Expand Search)
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20681
Image3_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif
Published 2024“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”
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20682
Image4_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif
Published 2024“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”
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20683
Table 1_IP-10 acts early in CV-A16 infection to induce BBB destruction and promote virus entry into the CNS by increasing TNF-α expression.docx
Published 2024“…We observed that the level of IP-10, as well as the TLR3-TRIF-TRAF3-TBK1-NF-κB and RIG-I/MDA5-MAVS-TRAFS-TBK1-NF-κB pathways, which are the upstream of IP-10, were significantly elevated during the course of CV-A16 infection. …”
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20684
Image2_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif
Published 2024“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”
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20685
Table 1_Serum creatinine to cystatin C ratio is a prognostic indicator in esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy.xlsx
Published 2025“…The results indicated that CCR had prognostic significance for the ESCC cases stratified according to subgroup analyses. …”
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20686
Image 1_Serum creatinine to cystatin C ratio is a prognostic indicator in esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy.jpeg
Published 2025“…The results indicated that CCR had prognostic significance for the ESCC cases stratified according to subgroup analyses. …”
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20687
Image 2_Serum creatinine to cystatin C ratio is a prognostic indicator in esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy.jpeg
Published 2025“…The results indicated that CCR had prognostic significance for the ESCC cases stratified according to subgroup analyses. …”
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20688
Table 2_Serum creatinine to cystatin C ratio is a prognostic indicator in esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy.docx
Published 2025“…The results indicated that CCR had prognostic significance for the ESCC cases stratified according to subgroup analyses. …”
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20689
Table 3_Radiation therapy induced intestinal barrier damage and repair process - differences in salivary metabolites and monitoring of intestinal barrier function.xlsx
Published 2025“…Purpose<p>Colorectal cancer (CRC) is still one of the most common malignant tumors, with gradual increase in its annual morbidity and mortality. But most cases are diagnosed in the late stage. For stage II-III cancer, clinical guidelines recommend surgery following neoadjuvant radiation therapy at ≥6 weeks after the last radiotherapy is completed. …”
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20690
High-intensity zones in dogs with lumbosacral intervertebral disc degeneration: insights from MRI and histopathological findings
Published 2025“…With this recognition, prospective analyses and their correlation with clinical presentations will be essential in determining the role and prognostic significance of HIZ.…”
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20691
Smart design and preclinical evaluation of folate-functionalized mesoporous nanoparticles for targeted paclitaxel delivery in cancer therapy
Published 2025“…<i>In vivo</i>, the MNPs containing paclitaxel enhanced the tumour targeting effect with the 87% of tumours observed with the treatment, while Taxol<sup>®</sup> was effective in only 65% of the cases, and free paclitaxel in 58%. These results highlight the promise of folate-decorated MNPs as an advanced nanocarrier for safer and more effective paclitaxel chemotherapy, with significantly reduced systemic toxicity compared to commercial Taxol<sup>®</sup>. …”
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20692
Image 1_Radiation therapy induced intestinal barrier damage and repair process - differences in salivary metabolites and monitoring of intestinal barrier function.jpeg
Published 2025“…Purpose<p>Colorectal cancer (CRC) is still one of the most common malignant tumors, with gradual increase in its annual morbidity and mortality. But most cases are diagnosed in the late stage. For stage II-III cancer, clinical guidelines recommend surgery following neoadjuvant radiation therapy at ≥6 weeks after the last radiotherapy is completed. …”
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20693
Table 1_Radiation therapy induced intestinal barrier damage and repair process - differences in salivary metabolites and monitoring of intestinal barrier function.docx
Published 2025“…Purpose<p>Colorectal cancer (CRC) is still one of the most common malignant tumors, with gradual increase in its annual morbidity and mortality. But most cases are diagnosed in the late stage. For stage II-III cancer, clinical guidelines recommend surgery following neoadjuvant radiation therapy at ≥6 weeks after the last radiotherapy is completed. …”
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20694
Data Sheet 1_Differential effects of isoflurane on auditory and visually evoked potentials in the cat.pdf
Published 2024“…We found that, in terms of their waveforms, (1) short-latency AEPs (BAERs) were the least affected while middle-latency AEPs were dramatically altered by isoflurane, and (2) short-latency VEPs was less persistent than that of short-latency AEPs, while both middle- and long-latency VEPs were largely suppressed by isoflurane and, in some cases, completely diminished. In addition, the signal strength in all but the middle-latency AEPs was significantly suppressed by isoflurane. …”
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20695
Table 2_Radiation therapy induced intestinal barrier damage and repair process - differences in salivary metabolites and monitoring of intestinal barrier function.xlsx
Published 2025“…Purpose<p>Colorectal cancer (CRC) is still one of the most common malignant tumors, with gradual increase in its annual morbidity and mortality. But most cases are diagnosed in the late stage. For stage II-III cancer, clinical guidelines recommend surgery following neoadjuvant radiation therapy at ≥6 weeks after the last radiotherapy is completed. …”
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20696
Supplementary Material for: Analysis of chromosome test results of 24,175 miscarried fetuses in Japan from 2000 to 2021
Published 2024“…., one of the largest clinical laboratories that has collected tissue specimens of products of conception derived from miscarried fetuses from hospitals throughout Japan from 2000. …”
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20697
Table 2_Downsizing chronic disease management programs for type 2 diabetes patients during the COVID-19 pandemic: changes in healthcare utilization patterns.docx
Published 2025“…In Q1 of 2020, type 2 diabetes patient visits to out-of-hours GP services rose notably, but decreased in Q1 of 2021, compared to 2019. Hospital care for diabetes showed a significant increase in Q2 of 2021 (+11.3%), compared to Q2 2019 and regular GP care increased from Q1 2021 (up to +11.1% in Q3 2021). …”
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20698
Table 5_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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20699
DataSheet1_Polystyrene microplastics exposition on human placental explants induces time-dependent cytotoxicity, oxidative stress and metabolic alterations.pdf
Published 2024“…Levels of mitochondrial and total superoxide anion (p < 0.01 and p < 0.05, respectively) and hydrogen peroxide (p < 0.001) were significantly elevated. PS-MP exposure resulted in a reduction in total sulfhydryl content (p < 0.05) and the activities of antioxidant enzymes superoxide dismutase (p < 0.01) and catalase (p < 0.05), while glutathione peroxidase activity increased (p < 0.05), and the oxidized/reduced glutathione ratio decreased (p < 0.05). …”
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20700
Effect of miR-7974 mimic transfection on proliferation of MDA-MB-453 cells together with changes in protein and gene expression levels of LC3B.
Published 2025“…<b>(B)</b> The fold change of total protein levels of LC3B between negative control/cells only samples and miR-7974-treated samples were statistically significant. <b>(C)</b> The gene expression levels of <i>LC3B</i> were decreased 72h after miR-7974 transfection of MBA-MB-453 cells compared to the negative control/cells-only samples. …”