Supplementary Material for: From childhood to adolescence: Long-term trends in severe obesity in German youth (2002–2023) حسب figshare admin karger (2628495)

"…Methods We analyzed data from the CrescNet auxological network including 1,495,401 clinical visits by 4-16-year-old children (2002-2023). …"

Data Sheet 1_Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders.docx حسب Nikola Habek (21178259)

"…Background<p>Preclinical and clinical research of insulin resistance and glucose homeostasis in metabolic disorders are essential. …"

Table 6_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx حسب Miguel Ângelo-Dias (20936444)

"…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"

SPSS data. حسب Myriam El Khoury-Malhame (14185996)

"…</p><p>Conclusion</p><p>Stigma remains a pervasive condition closely related to increased psychological suffering, decreased self-esteem and lower tendencies to seek help. …"

High-throughput single-cell analysis reveals Omp38-specific monoclonal antibodies that protect against <i>Acinetobacter baumannii</i> infection حسب Yiwei Zhang (1448599)

"…Intravenous administration of the Omp38-specific mAbs significantly improved the survival rate and reduced the bacterial load in a mouse model of lethal <i>A. baumannii</i> infection. …"

Image 1_A four-gene signature identified by integrated transcriptomic analysis for differential diagnosis and prognosis of uterine smooth muscle tumors.pdf حسب Huiyi Hu (11226995)

"…Moreover, survival analysis revealed the prognostic significance of this four-gene signature: high TOP2A with low ABLIM1, FHL5, and MAP3K8 expression correlated with decreased overall survival in ULMS, implicating their potential role as diagnostic and prognostic markers. …"

ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer حسب Ana García-García (17779885)

"…Genetic or chemical inhibition of ELOVL6 results in decreased proliferation and migration, accompanied by alterations in fatty acid elongation. …"

Data Sheet 1_Personalized temporal interference stimulation targeting striatum reduces functional stability and dynamic connectivity variability in the sensorimotor network.docx حسب Dongsheng Tang (5526149)

"…</p>Results<p>(1) Functional stability: TI stimulation significantly decreased functional stability in bilateral SMA regions (predominantly SMA proper, with parts of pre-SMA) compared to Sham and baseline conditions (P < 0.01). (2) Dynamic functional connectivity: TI stimulation reduced dFC variability between the right striatum and left SMA region (predominantly SMA proper, with parts of pre-SMA) compared to baseline (P < 0.01). (3) Safety: No adverse cognitive effects or side effects were observed, with good blinding effectiveness maintained throughout the study.…"

The Dataset used for Tables 1 and 3. حسب Mitsuyo Nonaka (20827083)

"…The intervention group showed significantly reduced weight (median; baseline 1, post-intervention 0.975, follow-up 0.983, p <  0.001), and slightly reduced waist circumference (median; baseline 1, post-intervention 0.975, follow-up 0.975, p =  0.226); however, the control group showed no change. …"

Table 1_Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study.docx حسب Weichao He (16832265)

"…Multivariate regression models revealed that encephalitis in Chinese children was significantly decreased by 18% with 1% increase in RDW after adjusting for all covariates (Adjusted OR = 0.82, 95% CI: 0.73–0.92). …"

Data Sheet 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf حسب Miguel Ângelo-Dias (20936444)

"…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"

Data Sheet 4_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf حسب Miguel Ângelo-Dias (20936444)

"…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"

Image 1_Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study.tif حسب Weichao He (16832265)

"…Multivariate regression models revealed that encephalitis in Chinese children was significantly decreased by 18% with 1% increase in RDW after adjusting for all covariates (Adjusted OR = 0.82, 95% CI: 0.73–0.92). …"

Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model حسب Merel Wauters (21333023)

"…Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …"

Image 3_H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study.tif حسب Hironori Goto (22307641)

"…Background<p>Epigenetic dysregulation plays a central role in pediatric acute myeloid leukemia (AML), yet its clinical relevance remains underexplored. This study primarily aimed to elucidate the clinical effect of H3K27me3 and H3K4me3 status on pediatric acute myeloid leukemia. …"

Image 1_H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study.jpeg حسب Hironori Goto (22307641)

"…Background<p>Epigenetic dysregulation plays a central role in pediatric acute myeloid leukemia (AML), yet its clinical relevance remains underexplored. This study primarily aimed to elucidate the clinical effect of H3K27me3 and H3K4me3 status on pediatric acute myeloid leukemia. …"

Table 1_H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study.docx حسب Hironori Goto (22307641)

"…Background<p>Epigenetic dysregulation plays a central role in pediatric acute myeloid leukemia (AML), yet its clinical relevance remains underexplored. This study primarily aimed to elucidate the clinical effect of H3K27me3 and H3K4me3 status on pediatric acute myeloid leukemia. …"

Image 2_H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study.jpeg حسب Hironori Goto (22307641)

"…Background<p>Epigenetic dysregulation plays a central role in pediatric acute myeloid leukemia (AML), yet its clinical relevance remains underexplored. This study primarily aimed to elucidate the clinical effect of H3K27me3 and H3K4me3 status on pediatric acute myeloid leukemia. …"

Table 2_H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study.docx حسب Hironori Goto (22307641)

"…Background<p>Epigenetic dysregulation plays a central role in pediatric acute myeloid leukemia (AML), yet its clinical relevance remains underexplored. This study primarily aimed to elucidate the clinical effect of H3K27me3 and H3K4me3 status on pediatric acute myeloid leukemia. …"

DataSheet1_Loading rate, geometry, and damage state influence vertical extraction biomechanics in an ex vivo swine dental model.DOCX حسب Timothy J. Gadzella (20515718)

"…The predictive power of the FEA model demonstrated in this study encourages its use in pre-clinical testing and development of new vertical extraction loading schemes for improving clinical outcomes.…"